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Found 28 Orthopedics trials

A listing of Orthopedics medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Topical Antibiotic Therapy to Reduce Infection After Operative Treatment of Fractures at High Risk of Infection: TOBRA

B
Brian Mullis, MD
18 - 80
All genders
Phase 3
Interventional
The overall objective is to compare the effect of Vancomycin and Tobramycin powder combined (treatment) to Vancomycin powder (control) in the reduction of post-fixation infections ofbial plateau and tibial pilon fractures at high risk of infection (collectively consideredhe "study injuries").
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A Multi-Center, Prospective Observational Study to Evaluate the Use of Patient-Specific Precision Injury Signatures to Optimize Orthopaedic Interventions in Multiply Injured Patients (PRECISE)

T
Todd McKinley, MD
18 - 55
All genders
The purpose of the PRECISE study (A multi-center, prospective observational study to evaluate the use of Patient-Specific Precision Injury Signatures to Optimize Orthopaedic Interventions in Multiply Injured Patients) is to evaluate how the human body responds to trauma and to treatment for traumatic injuries.
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Fracture-Related Outcome Study for Operatively Treated Tibia Shaft Fractures (FROST)

R
Roman Natoli, MD
18 or above
All genders
Observational
Approximately 1000 patients presenting with tibial shaft fractures (AO type 42) will bed prospectively in this registry. All patients are treated and followed at 6 weeks, 6hs and 1 year postoperative always following the local standard of care (routine) visithedule up to 36 months if required. Data collection includes patient …
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Distal Radius Interventions for Fracture Treatment (DRIFT)

E
Erika Daley
4 - 10
All genders
Interventional
This protocol describes a multicenter, prospective randomized superiority trial comparingunctional outcomes between children treated with sedated reduction versus no formalduction.
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Post Market Evaluation of Clinical Safety and Performance of the Fitbone Transport and Lengthening System

B
Brian Mullis, MD
21 or above
All genders
Observational
What is the purpose of this study?The goal of this observational study is to examine and confirm the clinical performance of the Fitbone Transport and Lengthening System in adult patients (21 years and older) who require lower-limb lengthening, fracture fixation and/or treatment for previous non-healing fracture. The main questions it aims …
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PREVENTion of Clot in Orthopaedic Trauma (PREVENT CLOT): A Randomized Pragmatic Trial Comparing the Complications and Safety of Blood Clot Prevention Medicines Used in Orthopaedic Trauma Patients

R
Roman Natoli, MD
100 or below
All genders
The purpose of this study is to help determine the best treatment for preventing blood clots that are formed following trauma that could potentially lead to death.
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Effect of Early Weight Bearing on Rehabilitation Outcomes in Patients with Traumatic Ankle and Tibial Plateau Fractures

R
Roman Natoli, MD
18 - 65
All genders
The purpose of this study is to compare the usual practice of bearing weight (“delayed weight bearing”) with weight bearing sooner in the healing process. We will use study data to determine if early weight bearing improves recovery after injury.
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Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT

K
Karl Shively
L
Luke A. Lopas, MD
18 - 64
All genders
Phase 3
Interventional
The proposed study is a multi-center, prospective randomized controlled trial comparingurrent standard of care treatment to the SEXTANT treatment protocol in patients with Typeures of the tibia and IIIB fractures of the ankle and hindfoot.
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