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Found 187 Cancer trials

A listing of Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Study on Monitoring and Chemotherapy for Germ Cell Tumors

S
Sandeep Batra, MD
49 years or below
All genders
Phase 3
This study investigates treatments for people with germ cell tumors, which are a type of cancer that starts in the cells that form sperm or eggs. The purpose of this study is to see how well active surveillance works for low-risk germ cell tumors and to compare two chemotherapy treatments, …
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Investigational Treatment for Relapsed Metastatic Germ Cell Tumor

J
Jennifer King
18 years - 100 years
All genders
This study investigates the use of an investigational medication in combination with oral etoposide for patients with relapsed metastatic germ cell tumor (GCT). Germ cell tumors are a type of cancer that begins in the cells that give rise to sperm or eggs. This study is designed to find out …
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Investigating Maintenance Treatment or Observation for Germ Cell Tumors

N
Nabil Adra, MD
18 years or above
All genders
Phase 2
Interventional
This study investigates maintenance treatment with oral etoposide or observation in patients with relapsed germ cell tumors (GCT) who have received high-dose chemotherapy and peripheral blood stem cell transplant. Germ cell tumors are a type of cancer that begins in the cells that give rise to sperm or eggs. This …
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Investigating an Investigational Medication for Certain Types of Cancer

B
Brian Weiss
12 months - 21 years
All genders
Phase 1/2
Interventional
This study investigates the use of an investigational medication in patients with relapsed or refractory solid tumors, including central nervous system tumors and lymphoma. The purpose is to find the best dose and understand the side effects and potential benefits. Solid tumors and lymphoma are types of cancer that can …
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Testis Cancer Surgery Study

T
Timothy Masterson
18 years - 100 years
All genders
This study investigates two different surgical techniques for treating testis cancer, focusing on retroperitoneal lymph node dissection (RPLND). The study compares the transperitoneal (TP) and extraperitoneal (EP) approaches. RPLND is a surgery to remove lymph nodes from the back of the abdomen. The purpose is to see if the EP …
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Research Study on Treatment Methods for Embryonal Tumor with Multilayered Rosettes in Children

S
Scott Coven
100 years or below
All genders
This study investigates treatments for children with Embryonal Tumor with Multilayered Rosettes (ETMR). ETMR is a rare type of brain tumor that occurs in young children. The purpose of the study is to understand how different treatments work for children who have been newly diagnosed with ETMR. Participants in this …
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A Study of DSP107 Alone and in Combination With Atezolizumab for Patients With Advanced Solid Tumors

R
Rohan Maniar
18 years or above
All genders
Phase 1/2
Interventional
What is the purpose of this study?Part 1: A first-in-human, open-label, Phase I dose escalation study of DSP107 monotherapy and combination therapy with atezolizumab in patients with advanced solid tumors. Part 2: Preliminary efficacy assessment of DSP107 in combination with atezolizumab in second or third line treatment of non small …
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Studying the Effects of an Investigational Medication in Breast Cancer

R
Rina Yadav
18 years or above
Female
Phase 2
This study investigates the effects of an investigational medication on premenopausal women with a specific type of breast cancer called estrogen receptor-positive, HER2-negative breast cancer. The purpose of the study is to understand how the investigational medication affects tumor cell growth compared to other treatments. The study is divided into …
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The Rare Brain Tumour Consortium Registry and Biobank

S
Scott Coven
18 years or below
All genders
What is the purpose of this study?The Biobank being created by this study is located at the Hospital for Sick Children in Toronto, Canada and is a research registry that collects biological samples and medical information from individuals in participating centers around the world. The purpose of this registry is …
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A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT

M
Marissa Just
30 years or below
All genders
Phase 2
Interventional
What is the purpose of this study?This phase II trial studies how well combination chemotherapy works in treating patients withwly diagnosed stage II-IV diffuse anaplastic Wilms tumors (DAWT) or favorable histology Wilms tumors (FHWT) that have come back (relapsed). Drugs used in chemotherapy regimens suchH-3 (vincristine, doxorubicin, cyclophosphamide, carboplatin, etoposide, …
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