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Found 181 Cancer trials

A listing of Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

J
Jennifer King
18 years or above
All genders
Phase 2
Interventional
What is the purpose of this study?Subjects with cT2-T3N0M0 urothelial cancer of the bladder will be enrolled. After completingwo cycles of pembrolizumab, subjects will undergo a restaging MRI of the abdomen and pelvis with a standard acquisition protocol (as outlined in the protocol) as well as CT chest. A CThe …
A
Anita Turk, MD
18 years or above
All genders
Phase 2
Interventional
This study investigates the use of an investigational medication along with a targeted therapy called olaparib for patients with metastatic pancreatic cancer. Metastatic pancreatic cancer is when the cancer has spread from the pancreas to other parts of the body. The study focuses on patients with specific genetic mutations called …
J
Jenny Belsky, DO
5 years - 60 years
All genders
Phase 3
Interventional
This study investigates the effects of adding immunotherapy to standard chemotherapy treatment for patients with early-stage classical Hodgkin lymphoma. Hodgkin lymphoma is a type of cancer that affects the lymphatic system, which is part of the body's immune system. The purpose of this study is to compare the survival rates …
B
Bryan Schneider, MD
18 years - 100 years
All genders
Phase 3
Interventional
What is the purpose of this study?This Phase III, randomized, open-label, multicenter study will evaluate the efficacy andy of giredestrant plus everolimus compared with the physician's choice of endocrineherapy plus everolimus in participants with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative locally advanced or metastatic breast cancer …
M
Mitesh Shah, MD
18 years - 100 years
All genders
Phase 4
Interventional
What is the purpose of this study?This study seeks to explore if GT, given its unique radiobiological and physical characteristics, may permit safe dose escalation and intensification and thereby provide a benefit to newly diagnosed GBM patients in terms of OS and LC when incorporated into the framework of the …
M
Monika Fischer, MD
18 years - 65 years
All genders
Phase 3
Interventional
What is the purpose of this study?The main aim of this study is to learn whether vedolizumab and upadacitinib given together (also called dual targeted therapy or DTT) reduces bowel inflammation and ulcers in the bowel compared to vedolizumab only (also called monotherapy) in adults with moderately or severely active …
A
Anna Maria Storniolo, MD
110 years or below
All genders
What is the purpose of this study?Adult patients (18 years of age and older) and pediatric patients (younger than 18 years of age) who are being evaluated for and/or treated for cancer at the NIH Clinical Center and at participating sites will be entered onto this tissue procurement protocol for …
M
Mateusz Opyrchal, MD, PhD
18 years - 100 years
All genders
Phase 1/2
This study investigates the safety and effects of an investigational medication in people with advanced solid tumors. Advanced solid tumors are cancers that have spread and do not respond well to regular treatments. The purpose of this study is to find out how safe the medication is, how the body …
S
Sandeep Batra, MD
1 year - 25 years
All genders
What is the purpose of this study?This study gathers health information for the Project: Every Child for younger patients with cancer. Gathering health information over time from younger patients with cancer may help doctors find better methods of treatment and on-going care. THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent …
C
Courtney Rowan, MD
1 years - 26 years
All genders
What is the purpose of this study?The goal of this study is to identify and validate response to therapy biomarkers for NIV respiratory support in children with ICCs. The central hypothesis is that response-to-therapy biomarkers can identify those most likely to benefit from intervention with NIV. The rationale is that …
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