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Found 166 Cancer trials
A listing of Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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Sandeep Batra, MD
This study investigates the effectiveness of adding an investigational medication to post-induction chemotherapy for patients with High-Risk B-cell Acute Lymphoblastic Leukemia (B-ALL). It also examines outcomes for patients with mixed phenotype acute leukemia (MPAL) and B-lymphoblastic lymphoma (B-LLy) treated with standard chemotherapy. B-ALL is a type of cancer that affects …
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Kathryn Nevel
This study investigates the effectiveness and safety of an investigational medication for people with IDH1-mutant glioma, a type of brain tumor. Gliomas are graded based on their severity, with Grade 2 and Grade 3 being less severe than Grade 4. The study has three parts: Part 1 looks at different …
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Jonathan L. Berkowitz, MD, PhD
This randomized research trial studies how well serum tumor marker directed disease monitoring works in monitoring patients with hormone receptor positive Her2 negative breast cancer that has spread to other places in the body. Using markers to prompt when scans should be ordered may be as good as the usual …
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Lauren Nephew
This study investigates what influences patients to choose biomarker-based surveillance for liver cancer instead of the standard image-based method. Hepatocellular cancer, or HCC, is a type of liver cancer. The study aims to understand the motivations or barriers for patients when deciding on this new type of surveillance.Participants will have …
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Lisa Landrum, MD, PhD, MS
What is the purpose of this study?This is a clinical trial to test letrozole in patients with uterine leiomyosarcoma. The main question is will treatment with letrozole extend progression-free survival in patients. Patients will receive 2/5 mg of letrozole daily. Translational Objectives: 1. To preliminarily assess IHC hormone receptor expression and correlation …
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Rita Assi
What is the purpose of this study?This MyeloMATCH Master Screening and Reassessment Protocol (MSRP) evaluates the use of a screening tool and specific laboratory tests to help improve participants' ability to register to clinical trials throughout the course of their myeloid cancer (acute myeloid leukemia or myelodysplastic syndrome) treatment. This …
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Julian Marin Acevedo
This study investigates lung screening in individuals at high risk for lung cancer who do not meet the United States Preventive Services Task Force (USPSTF) criteria. Lung cancer is a disease where cells in the lungs grow out of control. The purpose of the study is to understand the demographics, …
Development of a Genetic Algorithm to Predict Anthracycline-Induced Cardiomyopathy in Adult Patients
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Todd Skaar
What is the purpose of this study?The purpose of this prospective study is to assess the accuracy of four previously-studied genetic variations to predict the development of cardiomyopathy (i.e., a disease of the heart muscle that reduces the ability of your heart to pump blood to your body) in adult …
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Rita Assi
What is the purpose of this study?This phase II MyeloMATCH treatment trial tests whether the standard approach of cytarabine and daunorubicin in comparison to the following experimental regimens works to shrink cancer in patients with high risk acute myeloid leukemia (AML): 1) daunorubicin and cytarabine liposome alone; 2) cytarabine and …
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Jennifer Ivanovich
What is the purpose of this study?In partnership with Indiana Biosciences Research Institute, we will develop new models to study pediatric osteosarcoma. We will invite children with Li-Fraumeni syndrome, hereditary retinoblastoma syndrome, or Rothmund-Thompson syndrome to participate. These three syndromes are associated with an increased risk to develop osteosarcoma. THIS STUDY …
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