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Found 180 Cancer trials

A listing of Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Expanding Lung Cancer Screening to Persons who do not Meet the 2021 USPSTF Guidelines Criteria: A Study from End Lung Cancer Now

J
Julian Marin Acevedo
18 years - 100 years
All genders
What is the purpose of this study?The primary objective of this study is to estimate the proportion of individuals with lung cancer seen at Indiana University and Eskenazi Health Centers who do not meet the 2021 USPSTF criteria for lung cancer screening. THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent …
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Study on Effects of Investigational for Refractory Metastatic Colorectal Cancer in Minority Populations

A
Anita Turk, MD
18 years - 100 years
All genders
Phase 4
This study investigates the effects of an investigational medication on high blood pressure in patients with refractory metastatic colorectal cancer (mCRC) from minority groups, specifically Black/African American and Hispanic/Latino populations. High blood pressure, also known as hypertension, is when the force of blood against the artery walls is too high, …
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Investigational Study of Maintenance Therapy in Ovarian Cancer with HER2 Protein

J
Jessica Parker
18 years - 100 years
Female
Phase 3
This study investigates the effectiveness of an investigational medication in combination with another medication compared to the other medication alone as a first-line maintenance therapy for patients with HER2-expressing ovarian cancer. HER2 is a protein that can affect the growth of some cancer cells. This study focuses on advanced high-grade …
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Investigating a Combination Therapy for Advanced Breast Cancer

K
Kathy Miller, MD
18 years - 100 years
All genders
Phase 1
This study investigates the safety and effects of a combination treatment for locally advanced or metastatic breast cancer. Breast cancer is a disease where cells in the breast grow out of control. This study looks at an investigational medication made from the patient's own T cells, which are a type …
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Phase I trial of a chimeric (trastuzumab-like and pertuzumab-like) HER2 B cell peptide vaccine emulsified in ISA 720 adjuvant for locally advanced HER2 positive breast cancer

P
Pravin Kaumaya
18 years - 100 years
All genders
Phase 1
What is the purpose of this study?Primary Objectives1. To determine the safety and toxicity profile of a chimeric HER2 B-cell peptide vaccine in patients with high-risk HER2 positive breast cancer after completion of standard curative therapy and adjuvant HER2-directed antibody therapy2. To determine immune responses induced by a chimeric HER2 …
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Patient-Centered Clinical Effectiveness Research Priorities for Transitioning Children with Cancer from Hospital to Home

E
Emily Mueller, MD
17 years or below
All genders
What is the purpose of this study?The purpose of this study is to study the transition from an inpatient hospital admission to being at home by engaging with caregivers (parents, legal guardians, etc) of children of cancer as well as with healthcare providers that participate in this process with the …
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A Phase III Trial of One vs. Two Years of Maintenance Olaparib, with or without Bevacizumab, in Patients with BRCA1/2 Mutated or Homologous Recombination Deficient (HRD+) Ovarian Cancer Following Response to First Line Platinum-Based Chemotherapy

J
Jessica Parker Metter
18 years - 100 years
All genders
Phase 3
What is the purpose of this study?This phase III trial compares the effect of olaparib for one year versus two years, with or without bevacizumab, for the treatment of BRCA 1/2 mutated or homologous recombination deficient stage III or IV ovarian cancer. Olaparib is a polyadenosine 5'-diphosphoribose polymerase (PARP) enzyme …
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Study of Eye Health in Patients Using a Medication Being Studied for Cervical Cancer

S
Sharon E. Robertson
18 years - 100 years
Female
This study investigates the effects of an investigational medication on eye health in patients with recurrent or metastatic cervical cancer. Cervical cancer occurs when cells in the cervix grow uncontrollably. This study focuses on understanding any side effects related to the eyes that may arise from the treatment. A side …
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Study of Imaging and Treatment Agents for Breast Cancer

K
Kathy Miller, MD
18 years - 100 years
All genders
Phase 1
This study investigates how safe and effective two investigational agents, an imaging agent and a therapeutic agent, are for patients with advanced breast cancer. The imaging agent, called 68Ga-R11228, is used to locate specific tumor cells in the body. The therapeutic agent, 177Lu-R11228, is used for treatment. Both agents are …
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Understanding Money Issues for Breast Cancer Patients in Clinical Trials

K
Kathy Miller, MD
18 years - 100 years
All genders
This study investigates the financial barriers faced by breast cancer patients who participate in clinical trials. Breast cancer is a disease where cells in the breast grow uncontrollably. This study looks at costs like lost income, travel, and parking for patients enrolled in these trials.Participants will complete a one-time paper …
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