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Found 180 Cancer trials

A listing of Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

A Phase I Study of Intra-Tumoral Injections of Ex Vivo Expanded Natural Killer Cells in Children and Young Adults With Recurrent or Progressive Supratentorial Malignant Brain Tumors

S
Scott Coven
1 years - 38 years
All genders
Phase 1
What is this study about?This phase I trial tests the safety, side effects, and best dose of ex vivo expanded natural killer cells in treating patients with cancerous (malignant) tumors affecting the upper part of the brain (supratentorial) that have come back (recurrent) or that are growing, spreading, or getting …
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A Phase 1a/1b Study of the PI3Ka: RAS Breaker BBO-10203 in Subjects with Advanced Solid Tumors (The BREAKER-101 Trial)

M
Mateusz Opyrchal, MD, PhD
18 years - 100 years
All genders
Phase 1/2
What is the purpose of this study?Phase 1a Dose Escalation/Cohort Expansion BBO-10203 Monotherapy Primary: To evaluate the safety and tolerability of BBO-10203, an inhibitor of the PI3Kα:RAS interaction, in subjects with locally advanced unresectable or metastatic (ie, advanced) HER2-positive BC; HR-positive, HER2-negative BC; KRAS mutant NSCLC; and KRAS mutant CRC. Secondary: To evaluate …
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A Protocol for Children and Young Adults Diagnosed with a Central Nervous System (CNS) Tumor to Assess Cognitive, Quality of Life (QOL), and Comprehensive Effects of Therapies

S
Scott Coven
39 years or below
All genders
What is the purpose of this study?To longitudinally assess cognitive outcomes using an a neurocognitive screening battery in children and young adults diagnosed with a CNS tumor. To longitudinally assess the impact of specific therapies on the QOL in children and young adults diagnosed with a CNS tumor.To longitudinally assess …
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Investigating Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult (AYA) Childhood Cancer Survivors

S
Sandeep Batra, MD
15 years - 20 years
All genders
This study investigates a home-based physical activity program designed for Hispanic or Latino/Latina adolescent and young adult (AYA) childhood cancer survivors. After cancer treatment, some AYA survivors may experience long-term effects like weight gain, tiredness, and reduced fitness. Hispanic or Latino/Latina survivors might face a higher risk of these effects. …
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Research Study on Investigational Medication for HER2 Expressing Tumors

J
Jonathan L. Berkowitz, MD, PhD
18 years - 120 years
All genders
Phase 2
Interventional
This study investigates an investigational medication for treating certain tumors that express a protein called HER2. HER2 is a protein that can affect the growth of some cancer cells. The study includes different types of cancers such as bladder, biliary tract, cervical, endometrial, ovarian, pancreatic, and some rare tumors.Participants will …
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Study on Medication for Appetite Loss in Cancer

S
Susan Ballinger
18 years - 100 years
All genders
Phase 3
This study investigates the effects of an investigational medication on appetite loss in patients with advanced cancer. Advanced cancer means the cancer has spread to other parts of the body. The purpose of this study is to compare the investigational medication with another usual medication to see which one is …
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Study on Safety and Tolerability of Investigational Medication in Advanced Solid Tumors (types of cancer that form solid masses)

N
Nabil Adra, MD
15 years - 100 years
All genders
Phase 1
This study investigates the safety and tolerability of an investigational medication in people with advanced solid tumors. Advanced solid tumors are cancers that have spread and are difficult to treat. The purpose of this study is to find out if the investigational medication is safe and to determine the best …
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Study on Support for Cancer Patients

A
Alexia Torke
18 years - 100 years
All genders
This study investigates the impact of informational support versus spiritual care on patients with cancer. Cancer patients often face challenges in coping with their condition and making treatment decisions. Religion and spirituality can play significant roles in their experience. Therefore, this study will evaluate a spiritual care intervention delivered by …
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Investigational Treatment for Relapsed Metastatic Germ Cell Tumor

J
Jennifer King
18 years - 100 years
All genders
This study investigates the use of an investigational medication in combination with oral etoposide for patients with relapsed metastatic germ cell tumor (GCT). Germ cell tumors are a type of cancer that begins in the cells that give rise to sperm or eggs. This study is designed to find out …
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Investigating Treatment for Children with Favorable Histology Wilms Tumors

M
Marissa Just
30 years or below
All genders
Phase 3
This study investigates treatment strategies for children with favorable histology Wilms tumors (FHWT), which is a common type of kidney cancer in children. The study aims to use risk factors, such as tumor histology, biology, and response to therapy, to determine the most effective treatment plan. Wilms Tumor is a …
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