Found 166 Cancer trials
A listing of Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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Hristos Kaimakliotis, MD
This study investigates the safety and efficacy of intravesical nadofaragene firadenovec, either alone or in combination with chemotherapy or immunotherapy, in patients with high-grade Bacillus Calmette-Guerin (BCG) unresponsive non-muscle invasive bladder cancer (NMIBC). NMIBC is a type of bladder cancer that has not spread into the muscle layer of the …
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Rohan Maniar
What is the purpose of this study?This phase II Expanded Lung-MAP treatment trial tests how well amivantamab-subcutaneous (SC) works in treating patients patients with MET amplification non-small cell lung cancer. Amivantamab-SC is a drug that reduces extra copies of the MET gene, a change present in your tumor. Giving amivantamab-SC …
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Hristos Kaimakliotis, MD
This study investigates the effect of adding gemcitabine to intravesical Bacillus Calmette Guerin (BCG) for patients with recurrent non-muscle invasive bladder cancer. Non-muscle invasive bladder cancer is a type of cancer that affects the bladder but does not invade the muscle layer. Gemcitabine is a chemotherapy drug that stops cancer …
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Tareq Salous
This study investigates how well an investigational medication combination works in treating adults with untreated locally advanced or metastatic urothelial carcinoma with an FGFR3 genetic alteration. Urothelial carcinoma is a type of cancer that occurs in the urinary system. This study uses a combination of medications, including monoclonal antibodies, which …
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Sharon E. Robertson
This study investigates treatment options for high risk locally advanced cervical cancer, where the cancer has spread to nearby tissues or lymph nodes. The study compares two approaches: one with induction chemotherapy using an investigational medication and chemotherapy, followed by chemoradiation and maintenance therapy, and the other with just chemoradiation …
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Jennifer King
This study investigates treatments for advanced clear cell renal cell carcinoma, a type of kidney cancer. The purpose of this study is to compare the effects of an investigational medication combined with cabozantinib versus a placebo combined with cabozantinib. Participants in this study have advanced or metastatic clear cell renal …
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Utpal Dave, MD
This study investigates the potential benefits of using high dose chemotherapy followed by a patient's own stem cells, known as an autologous stem cell transplant, in treating peripheral T-cell lymphoma. Peripheral T-cell lymphoma is a type of cancer that affects T-cells, which are part of the body's immune system. The …
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Samantha Armstrong
What is the purpose of this study?This phase II trial compares the effect of immunotherapy (pembrolizumab) plus chemotherapy (doxorubicin) to chemotherapy (doxorubicin) alone in treating patients with undifferentiated pleomorphic sarcoma (UPS) or a related poorly differentiated sarcoma that has spread from where it first started to other places in the …
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Patricia Wolf
DID YOU KNOW?... Colorectal cancer(CRC) is the second leading cause of cancer death in the United States. CRC is a serious health problem in the U.S., and African American/Black individuals are affected more than others. What is this study about?This study will look at a nutrient called cysteine. We think that …
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Monika Fischer, MD
What is the purpose of this study?The main aim of this study is to learn whether vedolizumab and upadacitinib given together (also called dual targeted therapy or DTT) reduces bowel inflammation and ulcers in the bowel compared to vedolizumab only (also called monotherapy) in adults with moderately or severely active …
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