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Found 159 results for Cancer
A listing of Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Transperitoneal vs Extraperitoneal Retroperitoneal Lymph Node Dissection: A Prospective Randomized Controlled Trial
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Timothy Masterson
We intend to compare an alternative way of performing cancer surgery for those who have testis cancer. This alternative technique is called extraperitoneal RPLND which has been published in retrospective studies. Its benefits, however, remain to be proved in a prospective study. THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent …
Pnoc031: Protocol for Embryonal Tumor With Multilayered Rosettes (Etmr)
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Scott Coven
This is an open-label, comprehensive, iterative investigation of evaluating the use of induction chemotherapy, high-dose chemotherapy, and focal radiation therapy in children with newly diagnosed Embryonal Tumor With Multilayered Rosettes (ETMR).PRIMARY OBJECTIVES I. To determine the six-month progression-free survival (PFS6) of participants with newly diagnosed, gross-totally resected, non-metastatic ETMR, treated …
The Rare Brain Tumour Consortium Registry and Biobank
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Scott Coven
What is the purpose of this study?The Biobank being created by this study is located at the Hospital for Sick Children in Toronto, Canada and is a research registry that collects biological samples and medical information from individuals in participating centers around the world. The purpose of this registry is …
A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT
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Marissa Just
What is the purpose of this study?This phase II trial studies how well combination chemotherapy works in treating patients withwly diagnosed stage II-IV diffuse anaplastic Wilms tumors (DAWT) or favorable histology Wilms tumors (FHWT) that have come back (relapsed). Drugs used in chemotherapy regimens suchH-3 (vincristine, doxorubicin, cyclophosphamide, carboplatin, etoposide, …
Risk Adapted Treatment of Unilateral Favorable Histology Wilms Tumors (FHWT)
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Marissa Just
This phase III trial studies using risk factors in determining treatment for children with favorable tissue (histology) Wilms tumors (FHWT). Wilms Tumor is the most common type of kidney cancer in children, and FHWT is the most common subtype. Previous large clinical trials have established treatment plans that are likely …
Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)
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Mitesh Shah, MD
What is the purpose of this study?The objectives of this registry study are to evaluate real-world clinical outcomes andd outcomes that measure the effectiveness and safety of STaRT.THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not actively “recruited,” but are screened by their …
A Phase 2 Trial of Chemotherapy followed by Response-Based Whole Ventricular & Spinal Canal Irradiation (WVSCI) for Patients with Localized Non-Germinomatous Central Nervous System Germ Cell Tumor.
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Sandeep Batra, MD
What is the purpose of this study?This phase II trial studies the best approach to combine chemotherapy and radiation therapy (RT) based on the patient's response to induction chemotherapy in patients withgerminomatous germ cell tumors (NGGCT) that have not spread to other parts of the brainbody (localized). This study has …
A Registry Study for Children with Atypical Teratoid Rhabdoid Tumor (ATRT)
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Scott Coven
Study goals:To analyze the significance of treatment, clinical and molecular variables in predicting progression free survival (PFS) at 6 months (PFS6) from date of diagnosis.To create a well annotated ATRT biorepository for current and future studies through the collection of biospecimens, imaging and key clinical data.THIS STUDY IS ENROLLING BY …
Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors
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Brian Weiss
What is the purpose of this study?This phase I/II trial evaluates the highest safe dose, side effects, and possible benefits ofgavivint in treating patients with solid tumors that has come back (recurrent) or does notd to treatment (refractory). Tegavivint interferes with the binding of beta-catenin to TBL1, which may help …
Pilot Study of a Rapid Triadic Communication Intention Elicitation Intervention (PRECursOr) to Improve Supportive Oncology Care Delivery for Patients with Advanced, Incurable Cancer and their Caregivers
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Kristin Levoy
What is this study about?The purpose of this study is to help test an idea designed to foster more supportive talk between providers (doctors or nurse practitioners), patients, and caregivers during an outpatient oncology appointment. A caregiver is the person the patient identifies is primarily involved in their healthcare. This …
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