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Found 159 results for Cancer

A listing of Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Investigating the Temporal Relationship: Chemotherapy-Induced Peripheral Neuropathy in Children and Adolescents with Cancer

J
Jenny Belsky, DO
2 years - 20 years
All genders
Cancer treatment can sometimes lead to the development of a condition called peripheral neuropathy. This is when your arms, hands, legs, and feet may tingle, like they are asleep, or cause pain. We want to look at characteristics that might predict who will develop this condition. Only eligible patients that …

Lt-Care (Liver Transplant-Community Access for Referral Equity) Applied

L
Lauren Nephew
18 years - 75 years
All genders
A previous study (25857) focused on developing a multilevel intervention addressing health related variables and other social/structural barriers faced by patients as the most prominent way to acknowledge and improve LT referral equity. The LT-CARE intervention has been designed and as a part of this protocol, will be delivered to …

Adenovirus-specific Cytotoxic T-lymphocytes for Refractory Adenovirus Infection

S
Scott Goebel, MD
1 month - 79 years
All genders
Phase 2
Interventional
What is the purpose of this study?Related donor Adenovirus (ADV) specific cytotoxic T cells (CTLs) manufactured with theyi CliniMACS Prodigy Cytokine Capture System will be administered intravenously in inhildren, adolescents and young adults with refractory ADV infection post Allogeneic Hematopoietic Stem Cell Transplantation (AlloHSCT), with primary immunodeficiencies (PID) ord organ …

A Phase II trial Evaluating Safety and Efficacy of Epcoritamab with Gemcitabine, Dexamethasone, and Cisplatin (GDP) Salvage Chemotherapy in Relapsed Refractory Large B-cell Lymphoma

V
Varun Mittal
18 years - 100 years
All genders
Phase 2
The goal of this study:Estimate complete remission (CR) rate per the Lugano classification with a combination of epcoritamab and GDP in subjects with relapsed large cell lymphoma.Estimate overall response rate (ORR) per the Lugano classification with a combination of epcoritamab and GDP in subjects with relapsed large cell lymphoma.Estimate duration …

National Liver Cancer Screening Trial (TRACER)

N
Naga Chalasani, MD
18 years - 85 years
All genders
What is this study about?The National Liver Cancer Screening Trial is an adaptive randomized phase IV Trial comparing ultrasound-based versus biomarker-based screening in 5500 patients with cirrhosis from any etiology or patients with chronic hepatitis B infection. Eligible patients will be randomized in a 1:1 fashion to Arm A using …

Detection of late subclinical cardiovascular disease in testicular cancer survivors exposed to cisplatin chemotherapy and bone marrow transplant

N
Nabil Adra, MD
18 years - 100 years
Male
Testicular cancer (TC) is diagnosed in young adult males between ages 18-39 and TC treatment involves the use of platinum therapy (CBCT) which can have long-term cardiovascular effects. We are looking at cholesterol and hormone changes, as well as blood vessel changes for coronary artery disease or blockages in the …

Hpc Offered for Preserve Expansion

J
Jodi Skiles
12 years - 80 years
All genders
Ossium produces cryopreserved hematopoietic progenitor cell bone marrow (HPC, Marrow (Cryopreserved)) recovered from deceased organ donors using good manufacturing practice (GMP) processing, Ossium’s HPC, Marrow (Cryopreserved) is supplied in units suitable for transplantation by infusion, the same procedure used for transplantation of other sources of HPCs, such as live donor …

Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021)

S
Scott Coven
1 year - 25 years
All genders
Phase 1
Interventional
This phase I trial studies the side effects and best dose of trametinib and everolimus ing pediatric and young adult patients with gliomas that have come back (recurrent). Trametinib acts by targeting a protein in cells called MEK and disrupting tumor growth.verolimus is a drug that may block another pathway …

A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

J
Jenny Belsky, DO
5 years - 60 years
All genders
Phase 3
Interventional
This phase III trial compares the effect of adding immunotherapy (brentuximab vedotin and nivolumab) to standard treatment (chemotherapy with or without radiation) to the standard treatment alone in improving survival in patients with stage I and II classical Hodgkin lymphoma.  THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most …

A Study With Tovorafenib (DAY101) as a Treatment Option for Progressive, Relapsed, or Refractory Langerhans Cell Histiocytosis

A
Anthony Ross
180 days - 22 years
All genders
Phase 2
Interventional
This phase II trial tests the safety, side effects, best dose and activity of tovorafenib (DAY101) in treating patients with Langerhans cell histiocytosis that is growing, spreading, or getting worse (progressive), has come back (relapsed) after previous treatment, or does not respond to therapy (refractory). Langerhans cell histiocytosis is a …
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