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Found 159 results for Cancer

A listing of Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RDCRN PIDTC

M
Miriam Kim, DO
All genders
In this prospective and longitudinal natural history study, the aim is to identify variables that affect long-term outcomes following potentially life-saving Definitive Therapy (DT), which includes either 1) allogeneic hematopoietic cell transplant (HCT), or 2) autologous gene therapy (GT).

A Phase 2 Study Using Chemoimmunotherapy With Gemcitabine, Cisplatin and Nivolumab in Newly Diagnosed Nasopharyngeal Carcinoma (NPC)

M
Marissa Just
1 years - 21 years
All genders
Phase 2
This phase II trial tests how well nivolumab in combination with chemotherapy drugs along with radiation therapy works in treating patients with nasopharyngeal cancer. Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to …

A Phase 3, Multicenter, Prospective Open-Label Study to Evaluate the Diagnostic Performance of [18F]Fapi-74 Pet/Ct for the Detection of Metastatic Disease in Adults with Pancreatic Ductal Adenocarcinoma

C
Cindy Yuan
All genders
This is a multi-site, open-label, non-randomized, single dose study to assess the clinical utility of [¹⁸F]FAPI-74 PET/CT in the detection of metastatic disease in individuals with pathologically confirmed pancreatic ductal adenocarcinoma. THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not actively “recruited,” but are …

A Single Arm, Multicenter, Prospective, Open Label, Longitudinal Phase 3 Study of Prostate Specific Membrane Antigen (Psma) Positron Emission Tomography (Pet) Combined With Magnetic Resonance Imaging (Mri) Compared to Standard of Care (Soc) for the Detection of Prostate Cancer (Pca).

C
Clinton Bahler, MD
18 years - 100 years
Male
This is an open label, longitudinal Phase 3 study of prostate specific membrane antigen (PSMA) positron emission tomography (PET) combined with magnetic resonance imaging (MRI) compared to standard of care (SOC) for the detection of prostate cancer (PCa).THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, …

A multicenter safety study of unlicensed investigational cryopreserved cord blood units (CBUs) manufactured by the National Cord Blood Program (NCBP) and provided for unrelated hematopoietic stem cell transplantation of pediatric and adult patients

J
Jodi Skiles
All genders
The purpose of this study is to evaluate the safety of administration of the investigational cord blood units by carefully documenting all infusion-related problems. THIS STUDY IS ENROLLING BY INVITATION ONLY - The study will enroll an unlimited number of transplant recipients at participating US transplant centers (up to 10 at …

DxB-062-NSCLC: Collection of fresh blood from treatment naive or progressing Stage IV m1b NSCLC cancer patients.

V
Vijay Khatri
All genders
The purpose of this study is to collect fresh blood from treatment naive or progressing Stage IV M1b Non-Small Cell Lung cancer (NSCLC) patients for research and development purposes.If the patient is a potential subject the provider will discuss with patient and provide an informed consent for more information. THIS STUDY …

Ovarian Tissue Cryopreservation for Fertility Preservation in Pre and Post-Pubertal Children, Adolescents and Adults Facing a Fertility Threatening Diagnosis or Treatment Regimen

A
Amanda J. Saraf, DO
Female
What is the purpose of this study?Define and follow-up with the patients that undergo OTC for fertility preservation.Optimize techniques and quality assurance measures for freezing and thawing of ovarian tissue or gametesEstablish techniques for in vitro follicle maturation (IFM) or in vitro maturation of cumulus oocyte complexesInvestigate factors affecting successful …

Parent Social Buffering and Dyadic Music Intervention to Decrease Distress in Infants and Young Children during Hematopoietic Stem Cell Transplant and their Parents

S
Sheri Robb
All genders
The goal of the proposed study is to adapt an existing music-based intervention (Active Music Engagement; AME) using the ORBIT model, for infants and young children (3 years of age and under) undergoing stem cell transplant and their parents. Previous studies suggest that AME produces positive psychosocial outcomes for children …

A Randomized Phase 3 Trial of Fludarabine/Cytarabine/Gemtuzumab Ozogamicin With or Without Venetoclax in Children With Relapsed AML

S
Sandeep Batra, MD
29 days - 21 years
All genders
Phase 3
A study to evaluate if the randomized addition of venetoclax to a chemotherapy backbone (fludarabine/cytarabine/gemtuzumab ozogamicin [GO]) improves survival of children/adolescents/young adults with acute myeloid leukemia (AML) in 1st relapse who are unable to receive additional anthracyclines, or in 2nd relapse.THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with …

An International Pilot Study of Chemotherapy and Tyrosine Kinase Inhibitors with Blinatumomab in Patients with Newly-Diagnosed Philadelphia Chromosome-Positive or Abl-Class Philadelphia Chromosome-Like B-Cell Acute Lymphoblastic Leukemia

S
Sandeep Batra, MD
366 days - 42 years
All genders
Phase 3
This phase III trial compares the effect of the combination of blinatumomab with dasatinib or imatinib and standard chemotherapy versus dasatinib or imatinib and standard chemotherapy for treating patients with Philadelphia chromosome positive (PH+) or ABL-class Philadelphia chromosome-like (Ph-Like) B-Cell acute lymphoblastic leukemia (B-ALL). Blinatumomab is a bispecific antibody that …
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