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Found 166 Neoplasm trials

A listing of Neoplasm medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

A Phase 2 Study of EIK1001 in Combination with Pembrolizumab and Chemotherapy in Patients with Stage 4 Non-Small Cell Lung Cancer

R
Rohan Maniar
18 years - 100 years
All genders
Phase 2
What is the purpose of this study?This is a multicenter open-label phase 2 trial that aim to assess the safety, tolerability, and efficacy of EIK1001 in combination with standard of care in participants with both confirmed stage 4 squamous and non-squamous NSCLC who have not received prior systemic therapy for …
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Ovarian Tissue Cryopreservation for Fertility Preservation in Pre and Post-Pubertal Children, Adolescents and Adults Facing a Fertility Threatening Diagnosis or Treatment Regimen

A
Amanda J. Saraf, DO
17 years or below
Female
What is the purpose of this study?Define and follow-up with the patients that undergo OTC for fertility preservation.Optimize techniques and quality assurance measures for freezing and thawing of ovarian tissue or gametesEstablish techniques for in vitro follicle maturation (IFM) or in vitro maturation of cumulus oocyte complexesInvestigate factors affecting successful …
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Investigating Music Interventions for Reducing Stress in Young Children Undergoing a Procedure to Replace Damaged Cells

S
Sheri Robb
3 years or below
All genders
This study investigates how music can help reduce stress in young children undergoing stem cell transplants and their parents. The purpose is to adapt a music-based intervention called Active Music Engagement (AME) for children under 3 years old and their parents. This adaptation aims to decrease distress and improve coping …
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Urinary Trypsinogen-2 for Detecting Pancreatitis After Pancreas Surgery

N
Nicholas Zyromski, MD
18 years - 100 years
All genders
This study investigates the use of urinary trypsinogen-2 to detect post-pancreatectomy acute pancreatitis (PPAP). Pancreatectomy is a surgery to remove part or all of the pancreas. PPAP is a condition that can occur after this surgery, where the pancreas becomes inflamed. The purpose of this study is to see if …
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Research Study for Muscle-Invasive Bladder Cancer

T
Tareq Salous
18 years - 100 years
All genders
Phase 2
This study investigates muscle-invasive bladder cancer, a type of cancer that grows into the muscle layer of the bladder. The purpose is to see how well an investigational medication combined with another treatment works for this type of cancer. The study involves patients with muscle-invasive bladder cancer receiving treatment and …
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Investigating Chemotherapy-Induced Peripheral Neuropathy in Young Cancer Patients

J
Jenny Belsky, DO
2 years - 20 years
All genders
This study investigates chemotherapy-induced peripheral neuropathy in children and adolescents with cancer. Peripheral neuropathy is a condition where nerves outside the brain and spinal cord are damaged, often causing weakness, numbness, and pain, usually in the hands and feet. The purpose of this study is to describe the relationship between …
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Investigating Fairness in Liver Transplant Referrals

L
Lauren Nephew
18 years - 75 years
All genders
This study investigates how to improve fairness in liver transplant referrals. The purpose is to develop and test a program called LT-CARE, which aims to address barriers faced by patients, healthcare providers, and the health system. The study will be conducted in five community gastroenterology practices that serve groups experiencing …
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Investigation of an Investigational Medication for a Condition Involving Excess Mast Cells

C
Craig Sewell
18 years - 100 years
All genders
This study investigates a condition called systemic mastocytosis, where the body produces too many mast cells due to a change in the KIT gene. This can be advanced (AdvSM) or non-advanced (NonAdvSM). The investigational medication offered in this study aims to target the KIT gene change to reduce abnormal mast …
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Investigation of Treatment Combinations for Advanced Non-Small Cell Lung Cancer

R
Rohan Maniar
18 years - 100 years
All genders
Phase 2/3
This study investigates the effects of adding an investigational medication, cemiplimab, to the usual treatment of docetaxel and ramucirumab for patients with stage IV or recurrent non-small cell lung cancer. This type of lung cancer is advanced and may have returned after previous treatment. Cemiplimab is a monoclonal antibody that …
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Investigating the Effectiveness of Investigational Medicine in Metastatic or Recurrent Head and Neck Cancer

G
Greg Durm, MD
18 years - 100 years
All genders
Phase 3
This study investigates the effectiveness and safety of an investigational medication compared to the investigator's choice of monotherapy treatment in patients with head and neck squamous cell carcinoma (HNSCC) that is incurable, metastatic, or recurrent. HNSCC is a type of cancer that occurs in the squamous cells lining the head …
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