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Found 157 Neoplasm trials

A listing of Neoplasm medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

G
Greg Durm, MD
18 years - 100 years
All genders
Phase 3
This study investigates the effectiveness and safety of an investigational medication compared to the investigator's choice of monotherapy treatment in patients with head and neck squamous cell carcinoma (HNSCC) that is incurable, metastatic, or recurrent. HNSCC is a type of cancer that occurs in the squamous cells lining the head …
B
Bharathi Muthusamy
18 years - 100 years
All genders
What is the purpose of this study?This is a descriptive, cross-sectional study, which will involve a one-time survey for patients with lung cancer (any histology), pancreatic adenocarcinoma, renal cell carcinoma, and urothelial carcinoma.  Patients in this study will be recruited in a prospective basis during their in-person visit to the outpatient …
N
Naoyuki Saito, MD
18 years - 100 years
All genders
Phase 3
What is the purpose of this study?This phase III trial studies magnetic resonance imaging (MRI) surveillance and prophylactic cranial irradiation (PCI) to see how well they work compared to MRI surveillance alone in treating patients with small cell lung cancer. MRI scans are used to monitor the possible spread of …
H
Hristos Kaimakliotis, MD
18 years - 100 years
All genders
Phase 2
This study investigates the safety and efficacy of intravesical nadofaragene firadenovec, either alone or in combination with chemotherapy or immunotherapy, in patients with high-grade Bacillus Calmette-Guerin (BCG) unresponsive non-muscle invasive bladder cancer (NMIBC). NMIBC is a type of bladder cancer that has not spread into the muscle layer of the …
T
Tarah Ballinger, MD
18 years - 45 years
Female
Phase 2
What is the purpose of this study?This phase II trial tests whether low-dose aspirin can affect markers of inflammation in postpartum (after childbirth) patients with benign breast disease planning to have a breast biopsy. Chronic inflammation may increase the risk of postpartum related breast cancer. Low-dose aspirin is a non-steroidal …
S
Sandeep Batra, MD
40 years or below
All genders
Phase 2/3
Interventional
This study investigates the use of an investigational medication, cabozantinib, in combination with standard chemotherapy for patients with newly diagnosed osteosarcoma. Osteosarcoma is a type of bone cancer that typically affects the long bones in the body. Cabozantinib is a kinase inhibitor, which means it works by blocking specific enzymes …
A
Anthony Ross
180 days - 22 years
All genders
Phase 2
Interventional
This study investigates an investigational medication for treating Langerhans cell histiocytosis (LCH), a disease where the body makes too many immature Langerhans cells, a type of white blood cell. These cells can build up and form tumors in organs like bones, skin, and lungs, causing damage. The purpose of the …
H
Huda Salman
18 years - 100 years
All genders
Phase 1
This study investigates the safety of an investigational treatment using special immune cells called CAR-T cells for people with certain B cell cancers. B cell malignancies are cancers that affect a type of white blood cell. The study includes participants whose cancer has returned or not responded to previous treatments. …
R
Rohan Maniar
18 years - 100 years
All genders
Phase 2
What is the purpose of this study?This phase II Expanded Lung-MAP treatment trial tests how well amivantamab-subcutaneous (SC) works in treating patients patients with MET amplification non-small cell lung cancer. Amivantamab-SC is a drug that reduces extra copies of the MET gene, a change present in your tumor. Giving amivantamab-SC …
B
Brian Weiss
12 months - 22 years
All genders
Phase 1
This study investigates the safety and effects of an investigational medication when combined with radiation therapy in children with high grade glioma. High grade glioma is a type of cancer that occurs in the brain. The investigational medication works by blocking signals that make cancer cells grow, which may help …
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