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Found 164 Neoplasm trials

A listing of Neoplasm medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Investigating Chemotherapy-Induced Peripheral Neuropathy in Young Cancer Patients

J
Jenny Belsky, DO
2 years - 20 years
All genders
This study investigates chemotherapy-induced peripheral neuropathy in children and adolescents with cancer. Peripheral neuropathy is a condition where nerves outside the brain and spinal cord are damaged, often causing weakness, numbness, and pain, usually in the hands and feet. The purpose of this study is to describe the relationship between …
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Investigating Fairness in Liver Transplant Referrals

L
Lauren Nephew
18 years - 75 years
All genders
This study investigates how to improve fairness in liver transplant referrals. The purpose is to develop and test a program called LT-CARE, which aims to address barriers faced by patients, healthcare providers, and the health system. The study will be conducted in five community gastroenterology practices that serve groups experiencing …
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Investigation of an Investigational Medication for a Condition Involving Excess Mast Cells

C
Craig Sewell
18 years - 100 years
All genders
This study investigates a condition called systemic mastocytosis, where the body produces too many mast cells due to a change in the KIT gene. This can be advanced (AdvSM) or non-advanced (NonAdvSM). The investigational medication offered in this study aims to target the KIT gene change to reduce abnormal mast …
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Investigation of Treatment Combinations for Advanced Non-Small Cell Lung Cancer

R
Rohan Maniar
18 years - 100 years
All genders
Phase 2/3
This study investigates the effects of adding an investigational medication, cemiplimab, to the usual treatment of docetaxel and ramucirumab for patients with stage IV or recurrent non-small cell lung cancer. This type of lung cancer is advanced and may have returned after previous treatment. Cemiplimab is a monoclonal antibody that …
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Investigating the Effectiveness of Investigational Medicine in Metastatic or Recurrent Head and Neck Cancer

G
Greg Durm, MD
18 years - 100 years
All genders
Phase 3
This study investigates the effectiveness and safety of an investigational medication compared to the investigator's choice of monotherapy treatment in patients with head and neck squamous cell carcinoma (HNSCC) that is incurable, metastatic, or recurrent. HNSCC is a type of cancer that occurs in the squamous cells lining the head …
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Study of Investigational Combinations for Prostate Cancer

N
Nabil Adra, MD
18 years - 100 years
Male
Phase 2
This study investigates the effects of combining two investigational medications for treating prostate cancer that has spread and is resistant to standard treatments. The study focuses on adult male patients with prostate cancer that shows positive results on a specific type of scan. The purpose is to find out how …
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Cardiovascular Health Study in Testicular Cancer Survivors

N
Nabil Adra, MD
18 years - 100 years
Male
The purpose of this study is to investigate the long-term effects of chemotherapy and bone marrow transplant on the heart health of testicular cancer survivors. Testicular cancer often affects young adult males, and the treatment can include chemotherapy with platinum-based drugs. This study looks at changes in cholesterol, hormones, and …
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Stigma in Lung Cancer and Tobacco-Related Cancers

B
Bharathi Muthusamy
18 years - 100 years
All genders
This study investigates the stigma experienced by patients with lung cancer and other tobacco-related cancers, such as pancreatic adenocarcinoma, renal cell carcinoma, and urothelial carcinoma. A stigma is a mark of disgrace associated with a particular condition. The purpose of this study is to understand how stigma affects patients with …
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Studying the Safety and Effectiveness of Bladder-Administered Therapy for BCG-Unresponsive Bladder Cancer

H
Hristos Kaimakliotis, MD
18 years - 100 years
All genders
Phase 2
This study investigates the safety and efficacy of intravesical nadofaragene firadenovec, either alone or in combination with chemotherapy or immunotherapy, in patients with high-grade Bacillus Calmette-Guerin (BCG) unresponsive non-muscle invasive bladder cancer (NMIBC). NMIBC is a type of bladder cancer that has not spread into the muscle layer of the …
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Investigating Safety and Effectiveness of an Investigational Medication for Low-grade Upper Tract Urothelial Cancer

H
Hristos Kaimakliotis, MD
18 years - 100 years
All genders
Phase 1/2
This study investigates the safety and effectiveness of an investigational medication for adults with low-grade upper tract urothelial carcinoma (LG-UTUC). LG-UTUC is a type of cancer that occurs in the urinary system, specifically the upper part of the ureter and kidney. The study will involve a safety lead-in period for …
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