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Found 147 results for Neoplasm
A listing of Neoplasm medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Randomized prospective study comparing intrathecal morphine vs intravenous methadone for postoperative analgesia following retroperitoneal lymph node dissection (RPLND)
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Gulraj Singh Chawla
At Indiana University Adult Academic Health Center (AAHC), both intrathecal morphine and intravenous methadone are the standard of care for pain management in patients undergoing retroperitoneal lymph node dissections for primary testicular cancer, and both have had great success. In this study, we propose to compare their analgesic effectiveness at …
Expanding Lung Cancer Screening to Persons who do not Meet the 2021 USPSTF Guidelines Criteria: A Study from End Lung Cancer Now
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Julian Marin Acevedo
What is the purpose of this study?The primary objective of this study is to estimate the proportion of individuals with lung cancer seen at Indiana University and Eskenazi Health Centers who do not meet the 2021 USPSTF criteria for lung cancer screening. THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent …
A Phase III Trial of One vs. Two Years of Maintenance Olaparib, with or without Bevacizumab, in Patients with BRCA1/2 Mutated or Homologous Recombination Deficient (HRD+) Ovarian Cancer Following Response to First Line Platinum-Based Chemotherapy
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Jessica Parker Metter
What is the purpose of this study?This phase III trial compares the effect of olaparib for one year versus two years, with or without bevacizumab, for the treatment of BRCA 1/2 mutated or homologous recombination deficient stage III or IV ovarian cancer. Olaparib is a polyadenosine 5'-diphosphoribose polymerase (PARP) enzyme …
PSMA-PET to Guide Prostatectomy: A Sub-study
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Clinton Bahler, MD
This sub-study consists of a single treatment group of men that require a PET scan to guide their radical prostatectomy, every subject will receive an MRI and the PSMA (prostate specific membrane antigen) PET scan prior to their surgery to determine if the PSMA PET scan is helpful in detecting …
Implementation of the Family-Centered Adolescent Sperm Banking Decision Tool (Fast)
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Amanda J. Saraf, DO
The purpose of this study is to learn more about thoughts and experiences completing the FAST, a tool healthcare providers us as part of a fertility consult. This information may help us better incorporate the FAST into fertility consults at other healthcare institutions. THIS STUDY IS ENROLLING BY INVITATION ONLY - …
Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076)
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Jessica Parker Metter
What is the purpose of this study?The OnPrime study is a multi-center, randomized open-label phase 3 study evaluating the safety and efficacy of Olvi-Vec followed by platinum-doublet chemotherapy and bevacizumab compared to the Active Comparator Arm with Physician's Choice of chemotherapy and bevacizumab in women diagnosed with platinum-resistant/refractory ovarian cancer …
Testicular Tissue Cryopreservation for Fertility Preservation
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Amanda J. Saraf, DO
What is the purpose of this study?Testicular tissue cryopreservation is an experimental procedure where a young boy's testicular tissue is retrieved and frozen. This technique is reserved for young male patients who are not yet producing mature sperm, with the ultimate goal that their tissue may be used in the …
Comparing the Clinical Impact of Pancreatic Cyst Surveillance Programs
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Mohammad Al-Haddad, MD
The purpose of this study is to compare the two approaches for monitoring pancreatic cysts. The study doctors want to compare more frequent monitoring vs less frequent monitoring in order to learn which monitoring method leads to better outcome for patients with pancreatic cysts.THIS STUDY IS ENROLLING BY INVITATION ONLY …
Developing Interventions to Support the Management of Oral Anticancer Medications in Patients with Breast Cancer
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Kathy Miller, MD
The study aims to develop an early prototype intervention to support patients diagnosed with breast cancer who are receiving orally administered anticancer medication. In a previously approved pilot work, the study team identified design requirements and developed preliminary design concepts to address barriers related to the use of oral anticancer …
Phase Ib Trial of Abbv-637 or Abbv-155 in Combination With Eras-801 for Glioblastoma With Amplification of the Epidermal Growth Factor Receptor
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Kathryn Nevel
The researchers are doing this study to find out whether the drugs ABBV-637 and ABBV-155 are safe treatments that cause few or mild side effects when given alone or in combination with ERAS-801 in people with recurrent GBM.THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, …
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