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Found 165 Neoplasm trials

A listing of Neoplasm medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Evaluating Tolerability of Elective Pelvic Ultra Hypofractionated Irradiation Treatment (ePUHRT) with High Dose Rate Brachytherapy Boost for Unfavorable and Higher Risk Prostate Cancer

O
Omar Ishaq
18 years - 100 years
Male
What is the purpose of this study?The purpose of this study is to evaluate the tolerability and toxicity of combining two radiation therapy methods. Elective Pelvic Ultra Hypofractionated Irradiation Treatment (ePUHRT), which is an external beam radiotherapy with High Dose Rate Brachytherapy Boost (form of internal radiation where a cancer …
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International validation of a patient reported experience measure for GI endoscopy

D
Douglas Rex, MD
18 years - 100 years
All genders
Understanding patient experience at colonoscopy is important for quality of endoscopic practice and to maximize participation in screening programs for colorectal cancer.  The Newcastle ENDOPREM™ has been tested and validated in the UK. It is important to study whether this tool is valid when applied in different languages and different …
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Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy: A Prospective, Single-arm, Multi-center, Blinded-review, Phase 3 Diagnostic Performance Study

C
Clinton Bahler, MD
18 years - 100 years
Male
Phase 3
What is the purpose of this study?The aim for this study is to assess the diagnostic performance of 64Cu-SAR-bisPSMA PET to detect regional nodal metastases. THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not actively “recruited,” but are screened by their physician for appropriate …
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Understanding Stress and Race in Breast Cancer

T
Tarah Ballinger, MD
18 years - 100 years
All genders
This study investigates the connection between stress, race, and breast cancer. Breast cancer is a disease where cells in the breast grow uncontrollably. The study looks at how stress and racial differences may affect breast cancer types and outcomes.Participants will be part of two groups: one to develop a stress …
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Breast Cancer Treatment Monitoring Study

T
Tarah Ballinger, MD
18 years - 100 years
Female
This study investigates the use of the NearWave optical molecular monitoring system to track the progress of breast cancer treatment. The purpose is to see if this system can predict how well patients respond to chemotherapy before surgery. Breast cancer is a disease where cells in the breast grow uncontrollably. …
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Expanding Lung Cancer Screening to Persons who do not Meet the 2021 USPSTF Guidelines Criteria: A Study from End Lung Cancer Now

J
Julian Marin Acevedo
18 years - 100 years
All genders
What is the purpose of this study?The primary objective of this study is to estimate the proportion of individuals with lung cancer seen at Indiana University and Eskenazi Health Centers who do not meet the 2021 USPSTF criteria for lung cancer screening. THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent …
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Study on Effects of Investigational for Refractory Metastatic Colorectal Cancer in Minority Populations

A
Anita Turk, MD
18 years - 100 years
All genders
Phase 4
This study investigates the effects of an investigational medication on high blood pressure in patients with refractory metastatic colorectal cancer (mCRC) from minority groups, specifically Black/African American and Hispanic/Latino populations. High blood pressure, also known as hypertension, is when the force of blood against the artery walls is too high, …
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Investigational Study of Maintenance Therapy in Ovarian Cancer with HER2 Protein

J
Jessica Parker
18 years - 100 years
Female
Phase 3
This study investigates the effectiveness of an investigational medication in combination with another medication compared to the other medication alone as a first-line maintenance therapy for patients with HER2-expressing ovarian cancer. HER2 is a protein that can affect the growth of some cancer cells. This study focuses on advanced high-grade …
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Investigating a Combination Therapy for Advanced Breast Cancer

K
Kathy Miller, MD
18 years - 100 years
All genders
Phase 1
This study investigates the safety and effects of a combination treatment for locally advanced or metastatic breast cancer. Breast cancer is a disease where cells in the breast grow out of control. This study looks at an investigational medication made from the patient's own T cells, which are a type …
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Phase I trial of a chimeric (trastuzumab-like and pertuzumab-like) HER2 B cell peptide vaccine emulsified in ISA 720 adjuvant for locally advanced HER2 positive breast cancer

P
Pravin Kaumaya
18 years - 100 years
All genders
Phase 1
What is the purpose of this study?Primary Objectives1. To determine the safety and toxicity profile of a chimeric HER2 B-cell peptide vaccine in patients with high-risk HER2 positive breast cancer after completion of standard curative therapy and adjuvant HER2-directed antibody therapy2. To determine immune responses induced by a chimeric HER2 …
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