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Found 33 Chemotherapy trials

A listing of Chemotherapy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

R
Rita Assi
18 years and older
All genders
Phase 3
Interventional
What is the purpose of this study?This study is researching an experimental drug called odronextamab, referred to as study drug, when used in combination with chemotherapy. The study is focused on patients with diffuse large B-cell lymphoma (DLBCL) that have not been treated before (called "previously untreated"), have come back …
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L
Lisa Landrum, MD, PhD, MS
18 years and older
Female
Phase 2/3
Interventional
What is the purpose of this study?This phase II/III trial tests whether adding trastuzumab and hyaluronidase-oysk (Herceptin HylectaTM) or pertuzumab, trastuzumab and hyaluronidase-zzxf (PhesgoTM) to the usual chemotherapy (paclitaxel and carboplatin) works to shrink tumors in patients with HER2 positive endometrial serous carcinoma or carcinosarcoma. Trastuzumab and pertuzumab are monoclonal …
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G
Greg Durm, MD
18 years and older
All genders
Phase 3
Interventional
What is the purpose of this study?The main objective is to compare the efficacy of tarlatamab with standard of care (SOC) on prolonging overall survival (OS).THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not actively “recruited,” but are screened by their physician for …
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M
Michael Ferguson, MD
25 years and younger
All genders
Phase 3
Interventional
What is the purpose of this study?This is a 2-arm, randomized, open-label, multicenter, global, Phase 3 trial to evaluate the efficacy, safety, and tolerability of tovorafenib monotherapy versus standard of care (SoC) chemotherapy in patients with pediatric low-grade glioma (LGG) harboring an activating rapidly accelerated fibrosarcoma (RAF) alteration requiring front-line …
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V
Varun Mittal
18 years and older
All genders
Phase 2
Interventional
What is the purpose of this study?This is a research study being done to see if adding a drug called epcoritamab to “salvage chemotherapy” GDP (gemcitabine + cisplatin, with dexamethasone) will better treat cancer than using chemotherapy alone.  THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology …
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S
Sandeep Batra, MD
1-21 years
All genders
Phase 3
Interventional
What is the purpose of this study?Rhabdomyosarcoma is a type of cancer that occurs in the soft tissues in the body. This phaseutcomes in patients with very low risk rhabdomyosarcoma (VLR-RMS) while decreasing the burden of therapy using treatment with 24 weeks of vincristined dactinomycin (VA) and examines the use …
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S
Sandeep Batra, MD
3-30 years
All genders
Phase 2
Interventional
What is the purpose of this study?This phase II trial studies the best approach to combine chemotherapy and radiation therapy (RT) based on the patient's response to induction chemotherapy in patients withgerminomatous germ cell tumors (NGGCT) that have not spread to other parts of the brainbody (localized). This study has …
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M
Marissa Just
30 years and younger
All genders
Phase 2
Interventional
What is the purpose of this study?This phase II trial studies how well combination chemotherapy works in treating patients withwly diagnosed stage II-IV diffuse anaplastic Wilms tumors (DAWT) or favorable histology Wilms tumors (FHWT) that have come back (relapsed). Drugs used in chemotherapy regimens suchH-3 (vincristine, doxorubicin, cyclophosphamide, carboplatin, etoposide, …
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S
Sandeep Batra, MD
1-25 years
All genders
Phase 3
Interventional
What is the purpose of this study?This phase III trial studies whether inotuzumab ozogamicin added to post-induction chemotherapy for patients with High-Risk B-cell Acute Lymphoblastic Leukemia (B-ALL) improves outcomes. This trial also studies the outcomes of patients with mixed phenotype acute leukemia (MPAL), and B-lymphoblastic lymphoma (B-LLy) when treated with …
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J
Jessica Parker Metter
18-100 years
Female
Phase 3
Interventional
What is the purpose of this study?The OnPrime study is a multi-center, randomized open-label phase 3 study evaluating the safety and efficacy of Olvi-Vec followed by platinum-doublet chemotherapy and bevacizumab compared to the Active Comparator Arm with Physician's Choice of chemotherapy and bevacizumab in women diagnosed with platinum-resistant/refractory ovarian cancer …
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