A listing of chemotherapy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This study investigates chemotherapy-induced peripheral neuropathy in children and adolescents with cancer. Peripheral neuropathy is a condition where nerves outside the brain and spinal cord are damaged, often causing weakness, numbness, and pain, usually in the hands and feet. The purpose of this study is to describe the relationship between …
This study investigates the use of the NearWave optical molecular monitoring system to track the progress of breast cancer treatment. The purpose is to see if this system can predict how well patients respond to chemotherapy before surgery. Breast cancer is a disease where cells in the breast grow uncontrollably. …
This study investigates the use of an investigational medication in combination with oral etoposide for patients with relapsed metastatic germ cell tumor (GCT). Germ cell tumors are a type of cancer that begins in the cells that give rise to sperm or eggs. This study is designed to find out …
What is the purpose of this study?This phase III trial compares standard chemotherapy to therapy with liposome-encapsulated daunorubicin-cytarabine (CPX-351) and/or gilteritinib for patients with newly diagnosed acuteyeloid leukemia with or without FLT3 mutations. Drugs used in chemotherapy, such as daunorubicin, cytarabine, and gemtuzumab ozogamicin, work in different ways to stop …
This study investigates the treatment of metastatic castration-resistant prostate cancer (mCRPC), which is a type of cancer that continues to grow even when the amount of testosterone in the body is reduced to very low levels. The purpose of this study is to compare overall survival between participants receiving an …
This study investigates the use of an investigational medication, cabozantinib, in combination with standard chemotherapy for patients with newly diagnosed osteosarcoma. Osteosarcoma is a type of bone cancer that typically affects the long bones in the body. Cabozantinib is a kinase inhibitor, which means it works by blocking specific enzymes …
This study investigates the addition of investigational medication and investigational immunotherapy to the usual chemotherapy for infants with newly diagnosed acute lymphoblastic leukemia (ALL). ALL is a type of cancer where the bone marrow makes too many immature lymphocytes (a type of white blood cell). In this study, the researchers …
This study investigates the safety and efficacy of intravesical nadofaragene firadenovec, either alone or in combination with chemotherapy or immunotherapy, in patients with high-grade Bacillus Calmette-Guerin (BCG) unresponsive non-muscle invasive bladder cancer (NMIBC). NMIBC is a type of bladder cancer that has not spread into the muscle layer of the …
This study investigates the effectiveness of adding an investigational medication to post-induction chemotherapy for patients with High-Risk B-cell Acute Lymphoblastic Leukemia (B-ALL). It also examines outcomes for patients with mixed phenotype acute leukemia (MPAL) and B-lymphoblastic lymphoma (B-LLy) treated with standard chemotherapy. B-ALL is a type of cancer that affects …
What is the purpose of this study?This phase II trial studies how well lower dose radiotherapy after chemotherapy works in treating children with central nervous system (CNS) germinomas. Radiation therapy uses high energy x-rays, particles, or radioactive seeds to kill cancer cells and shrink tumors. Carboplatin is in a class …