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Found 26 liver-disorders trials

A listing of liver-disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

OnX Liver Assessment Solution Clinical Study

R
Raj Vuppalanchi, MD
22 years - 80 years
All genders
Interventional
What is the purpose of this study?This protocol’s primary aim is to assess the performance of the OnX exam on patients with suspected or confirmed liver disease with the goal of comparing the OnX output stiffness estimates to FibroScan® liver stiffness measurements. Our primary objectives are to assess whether the …
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Characterization of Patients Referred to Indiana University for Evaluation and Management of Suspected Nonalcoholic Fatty Liver Disease

N
Niharika Samala, MD
18 years - 100 years
All genders
What is this study about?Patients with nonalcoholic fatty liver disease have varied etiologies, associated risk factors and disease severity.  One purpose of this study is to determine the possible etiological factors, risk factors, and disease severity of all patients referred to Digestive and Liver Diseases Clinics for presumed NAFLD.  Another …
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Investigating Kidney Function Recovery in Patients Undergoing Both Liver and Kidney Transplants

M
Muhammad Jan
18 years - 100 years
All genders
This study investigates how kidney function recovers after a person receives both a liver and a kidney transplant. The purpose of this study is to see if having a liver transplant alone can improve kidney function enough that a kidney transplant might not be needed. This study is for people …
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Microbiome alterations in the setting of intestinal failure associated liver disease

K
Katie Huff
18 months or below
All genders
What is the purpose of this study?Neonates who require prolonged IV nutrition (TPN) are at risk for such complications as intestinal failure associated liver disease (IFALD). In addition, it is also known that TPN and lack of nutrition through the GI tract influences the intestinal microbiome or bacteria present in …
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National Liver Cancer Screening Trial (TRACER)

N
Naga Chalasani, MD
18 years - 85 years
All genders
What is this study about?The National Liver Cancer Screening Trial is an adaptive randomized phase IV Trial comparing ultrasound-based versus biomarker-based screening in 5500 patients with cirrhosis from any etiology or patients with chronic hepatitis B infection. Eligible patients will be randomized in a 1:1 fashion to Arm A using …
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Effect of the HCC-EduLink Intervention

L
Lauren Nephew
18 years - 100 years
All genders
The objective of this study is to pilot test a multi-level intervention designed to address patient- and system-level social and structural determinants of health (SSDOH) variables and facilitate access to curative hepatocellular carcinoma (HCC) therapies, including liver transplantation and resection, in a cohort of Black patients with Barcelona Clinic Liver …
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Measuring Patient Reported Needs in Outpatient Liver Disease Management

A
Archita Desai, MD
18 years - 100 years
All genders
Observational
What is the purpose of this study?Patients with chronic liver disease (CLD) are biopsychosocially complex and represent a vulnerable population at high risk for poor health-related outcomes. Beyond their primary liver disease, individuals with CLD often have unmet social needs which serve as important social determinants of health (SODH). For …
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Study of Investigational Medication in Individuals with Liver Disease

R
Raj Vuppalanchi, MD
18 years - 80 years
All genders
Phase 1
Interventional
This study investigates the effects of an investigational medication on people with moderate liver problems and cirrhosis caused by a liver condition called cholestatic liver disease. The purpose is to understand how the body processes the medication and how safe it is for these individuals. Cirrhosis is a condition where …
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Functional Assessment in Liver Transplantation (FrAILT) Study

M
Marwan Ghabril
18 years - 100 years
All genders
Observational
What is the purpose of this study?This will be a prospective cohort study of patients with liver disease. Subjects will undergo geriatric assessments of frailty, functional status, and disability using functional status measures at baseline and at every clinic visit in the pre-transplant setting. Subjects will also answer questions regarding …
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Functional Assessment in Liver Transplant Candidates (FrAILT) Study

M
Marwan Ghabril
18 years - 100 years
All genders
Interventional
What is this study about?This will be a prospective cohort study of patients with liver disease. The researchers want to gather information through a series of various tests that can be used in the future to guide diagnosis and treatment of cognitive impairment including Alzheimer’s and related dementias in individuals …
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