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Found 23 liver-disorders trials
A listing of liver-disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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Chao Jarasvaraparn
What is the purpose of this study?Chronic liver disease (CLD) in children can be caused by a variety of conditions and have serious consequences if left untreated. Liver organoids are defined as 3D structure derived from human liver tissue and is a promising new approach to treating liver disease in …
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Suthat Liangpunsakul, MD
What is the purpose of this study?NADPH oxidase 2 (NOX2) is the isoform of NOX found in phagocytes including neutrophils, NOX2 activation generates reactive oxygen species (ROS) with antimicrobial activities. Patients with advanced alcoholic cirrhosis or alcoholic hepatitis are more susceptible to infections due to deficient ROS production by neutrophils. …
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Raj Vuppalanchi, MD
This study investigates metabolic dysfunction-associated steatotic liver disease (MASLD), a condition where fat builds up in the liver due to metabolic issues. The purpose of this study is to assess the safety and effectiveness of different investigational medications for adults with MASLD who are at high risk of serious liver …
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Katie Huff
What is the purpose of this study?Neonates who require prolonged IV nutrition (TPN) are at risk for such complications as intestinal failure associated liver disease (IFALD). In addition, it is also known that TPN and lack of nutrition through the GI tract influences the intestinal microbiome or bacteria present in …
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Lauren Nephew
This study investigates barriers to alcohol use disorder treatment in patients with alcohol-associated liver disease. The purpose of this study is to understand how different factors, like stigma and transportation issues, affect patients' willingness to engage in treatment. Alcohol use disorder (AUD) is when someone cannot control their drinking despite …
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Samer Gawrieh, MD
This study investigates the effects of an investigational medication on people with Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) who also have Human Immunodeficiency Virus (HIV). MASLD is a condition where fat builds up in the liver, and this study aims to see if the investigational medication can reduce this fat. …
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Naga Chalasani, MD
What is the purpose of this study?The aim of this study is to collect a small sample of liver tissue and approximately 15mL of blood from patients who are undergoing elective liver biopsies for clinical purposes to establish and grow a liver tissue bank. The samples will be used for …
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Abby Russi
This study investigates the immune responses in children who have had a liver transplant. The purpose is to understand how the body's immune system acts before and during a problem called acute cellular rejection, which can happen after a transplant. Acute cellular rejection is when the body's immune system attacks …
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Naga Chalasani, MD
What is this study about?The National Liver Cancer Screening Trial is an adaptive randomized phase IV Trial comparing ultrasound-based versus biomarker-based screening in 5500 patients with cirrhosis from any etiology or patients with chronic hepatitis B infection. Eligible patients will be randomized in a 1:1 fashion to Arm A using …
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Lauren Nephew
This study investigates how to improve fairness in liver transplant referrals. The purpose is to develop and test a program called LT-CARE, which aims to address barriers faced by patients, healthcare providers, and the health system. The study will be conducted in five community gastroenterology practices that serve groups experiencing …
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