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Found 66 Surgery trials

A listing of Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

SURG-DUKE-CEPPA-VAC; A Randomized Phase II Evaluation of Negative Pressure Wound Therapy for Reduction of Postoperative Surgical Site Infection in Patients Undergoing Colorectal and Hepatopancreatobiliary Surgery

E
Eugene Ceppa, MD
18 - 100
All genders
The purpose of this study is to compare the rate of surgical site infection between traditional wound care and negative pressure wound therapy.
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Understanding Mechanisms of Implant Associated Complications

M
Mithun Sinha
18 - 100
All genders
This study aims to elucidate the molecular mechanisms associated with implant complications.
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Intranasal Povidone Iodine (PVI) to Prevent Staphylococcus aureus

T
Todd McKinley, MD
18 - 100
All genders
Phase 4
The purpose of this research study is to find out if applying iodine to the inside of the nose prevents Staph infections among patients having operations to fix broken bones.
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Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT

K
Karl Shively
L
Luke A. Lopas, MD
18 - 64
All genders
Phase 3
Interventional
The proposed study is a multi-center, prospective randomized controlled trial comparingurrent standard of care treatment to the SEXTANT treatment protocol in patients with Typeures of the tibia and IIIB fractures of the ankle and hindfoot.
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COgnitive and Physical Exercise to Improve Outcomes After Surgery (COPE-iOS) Study (COPEiOS)

R
Roman Natoli, MD
60 or above
All genders
Interventional
The COgnitive and Physical Exercise to improve Outcomes after Surgery (COPE-iOS) study isg the hypothesis that a pragmatic program combining computerized cognitive training andhysical training throughout the perioperative period will improve long-term cognitive and disability outcomes in older surgical patients at high risk for decline. To accomplish these goals, the …
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Topical Antibiotic Therapy to Reduce Infection After Operative Treatment of Fractures at High Risk of Infection: TOBRA

B
Brian Mullis, MD
18 - 80
All genders
Phase 3
Interventional
The overall objective is to compare the effect of Vancomycin and Tobramycin powder combined (treatment) to Vancomycin powder (control) in the reduction of post-fixation infections ofbial plateau and tibial pilon fractures at high risk of infection (collectively consideredhe "study injuries").
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Biomarkers for Fluid Overload after Pediatric Cardiac Surgery

C
Courtney Rowan, MD
18 or below
All genders
People who undergo heart surgery are at risk for accumulating extra fluid in the body, which may negatively affect the body’s ability to heal after surgery. The purpose of this research is to determine if markers in your blood can help identify those patients who are at greatest risk for …
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STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic Pancreatitis (STTEPP)

E
Evan Fogel, MD
18 or above
All genders
Phase 1
Interventional
The investigators propose to conduct a dose-escalation trial of an FDA-approved antiepileptic drug, lacosamide, added to opioid therapy in patients with chronic abdominal pain fromhronic pancreatitis (CP). This pilot trial will test the feasibility of the study design andvide reassurance regarding the tolerability and safety of lacosamide used concomitantly with …
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A Prospective, Single-arm, Multi-center, Open-label Trial Evaluating the Continuous Application of Prevena Therapy for up to 14 days

L
Leonard Buller
22 or above
All genders
Interventional
What is the purpose of this study?The purpose of this study is to demonstrate substantial equivalence in terms of safety to support an indication change related to the usage of Prevena Therapy for up to 14 days.  THIS STUDY IS ENROLLING BY INVITATION ONLY - The Principal Investigator will review the …
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How COVID-19 pandemic affects bariatric surgery patients

D
Dimitrios Stefanidis, MD
18 - 100
All genders
Observational
The purpose of this study is to evaluate the effect of the pandemic we are going through has in our patients and investigate whether it causes them any issues long-term.
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