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Found 66 Surgery trials

A listing of Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Serum Protein-Based Indices for the Progression of Fracture Healing and Nonunion

R
Roman Natoli, MD
18 - 70
All genders
To define a serum protein-based diagnostic for the progression and failure of fracture healing, through the identification of a set of serum proteins that appear at early times of biological healing and show a specific correlation with later radiological and functional signs used to define delayed healing and non-union. 
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Early Serial Sampling of Peripheral Blood for the Purposes of Predicting Fracture Nonunion

R
Roman Natoli, MD
18 - 60
All genders
The purpose of this study is to determine if certain molecules in the bloodstream can be used to improve our ability to predict the development of a nonunion or unhealed bone or fracture related infection.  This study is looking at many molecules and we will determine if the levels of …
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Molecular Mechanisms Associated with Breast Implant Complications

M
Mithun Sinha
18 - 100
Female
In recent years, many complications have been attributed to breast implants including chronic fatigue and other symptoms associated with autoimmune diseases, called Breast Implant Illness (BII). Some women have even developed a rare type of T-cell non-Hodgkin’s lymphoma around their breast implants, called BIA-ALCL. Hundreds of women have been affected …
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Cast or Operation for Medial Epicondyle Fracture Treatment in Children (COMET)

E
Erika Daley
7 - 17
All genders
Interventional
This protocol describes a multicenter, prospective randomized superiority trial of medialdyle fracture treatments comparing functional outcomes between children treated withve reduction and fixation or non-operative immobilization.
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Post-approval Study of Transcarotid Artery Revascularization in Standard Risk Patients With Significant Carotid Artery Disease

R
Raghu Motaganahalli, MD
18 - 79
All genders
Observational
The study objective is to evaluate real world usage of the ENROUTE Transcarotid Stent when used with the ENROUTE Transcarotid Neuroprotection System in patients at standard risk fordverse events from carotid endarterectomy
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Effect of NSAIDs on Union, Opioid Utilization and Pain Management for Tibia Fractures

K
Karl Shively
B
Brian Mullis, MD
18 - 80
All genders
Phase 3
Interventional
The proposed study is a two arm, pragmatic, randomized controlled multicenter Phase IIIy trial. 1,000 patients with tibia fractures treated with intramedullary (IM)will be randomized into two treatment arms. The control arm will receive standard paingement and no NSAIDs. The treatment arm will receive standard pain management plus up toweeks …
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Precision Medicine Approach Based on Discrete Time Windows for Predicting Outcomes of Polytrauma Patients (Windows)

T
Todd McKinley, MD
18 - 55
All genders
Observational
The goal of this project is to obtain blood samples and test to see how each individual’s body is responding to traumatic injuries in order to better understand how to treat patients with injuries like these in the future.
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A Multi-Center, Prospective Observational Study to Evaluate the Use of Patient-Specific Precision Injury Signatures to Optimize Orthopaedic Interventions in Multiply Injured Patients (PRECISE)

T
Todd McKinley, MD
18 - 55
All genders
The purpose of the PRECISE study (A multi-center, prospective observational study to evaluate the use of Patient-Specific Precision Injury Signatures to Optimize Orthopaedic Interventions in Multiply Injured Patients) is to evaluate how the human body responds to trauma and to treatment for traumatic injuries.
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Fracture-Related Outcome Study for Operatively Treated Tibia Shaft Fractures (FROST)

R
Roman Natoli, MD
18 or above
All genders
Observational
Approximately 1000 patients presenting with tibial shaft fractures (AO type 42) will bed prospectively in this registry. All patients are treated and followed at 6 weeks, 6hs and 1 year postoperative always following the local standard of care (routine) visithedule up to 36 months if required. Data collection includes patient …
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Analysis of Rhinologic and Olfactory Outcomes in Patients Testing Positive for COVID-19

J
Jonathan Ting, MD
18 - 100
All genders
Observational
The purpose of this study is to understand what the symptoms of patients that get COVID-19 are like at first and then how these symptoms change with time. We hope that by understanding these specific symptoms that patients with COVID-19 can be identified earlier and potentially treated earlier as well.
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