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Found 76 surgery trials

A listing of surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Investigation of Meniscus Treatment Outcomes in Children and Adolescents

G
Gunnar Tysklind
19 years or below
All genders
Observational
This study investigates the outcomes of treating meniscus tears and discoid meniscus issues in children and adolescents under the age of 19. The purpose is to collect data over a long period from different centers to understand the best way to treat these conditions. The meniscus is a piece of …
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Investigating Treatment Deintensification for HPV-Positive Oropharyngeal Cancer

M
Michael W. Sim, MD
18 years - 100 years
All genders
This study investigates a new approach for treating HPV-positive oropharyngeal squamous cell carcinoma (OPSCC). The purpose of this study is to see if reducing the intensity of treatment, based on levels of ctHPVDNA (pieces of cancer DNA in blood samples), can be as effective as the standard treatment. OPSCC is …
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Utility of Serum Biomarkers in Diagnosing Fracture-Related Infections: A Pilot Study

R
Roman Natoli, MD
18 years - 85 years
Accepts healthy volunteer
All genders
The primary aim will be to determine if serum inflammatory biomarkers can reliably diagnose FRIs as compared to a standardized definition of FRI.
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Cast or Operation for Medial Epicondyle Fracture Treatment in Children (COMET)

E
Erika Daley
7 years - 17 years
All genders
Interventional
This protocol describes a multicenter, prospective randomized superiority trial of medialdyle fracture treatments comparing functional outcomes between children treated withve reduction and fixation or non-operative immobilization.
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Study on Pain Relief Methods After Heart Surgery in Young Children

B
Brandon Tanner
6 years or below
All genders
Phase 1
Interventional
This study investigates the effectiveness and safety of different pain relief methods after heart surgery in young children. The purpose is to compare two types of pain relief: an investigational medication and bupivacaine HCl, which are used to reduce pain after surgery. The study involves children aged 0 to less …
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A Prospective, Single-Arm Multi-Center Study of the HARMONIC 700, 5 mm Diameter Shears with Advanced Hemostasis in Pediatric Surgical Procedures (General) and Adult Surgical Procedures (General, Gynecological, Urological, and Thoracic)

T
Troy Markel, MD
110 years or below
All genders
Interventional
What is the purpose of this study?The main purpose of this study is to demonstrate acceptable performance and assess safety of the HARMONIC 700 Shears device in a post-market setting when used per the instructions for use in pediatric and adult surgical procedures.THIS STUDY IS ENROLLING BY INVITATION ONLY - …
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PREVENTion of Clot in Orthopaedic Trauma (PREVENT CLOT): A Randomized Pragmatic Trial Comparing the Complications and Safety of Blood Clot Prevention Medicines Used in Orthopaedic Trauma Patients

R
Roman Natoli, MD
100 years or below
All genders
The purpose of this research study is to help determine the best treatment for preventing blood clots that are formed following trauma that could potentially lead to death. At the moment researchers do not know if using medications called low molecular weight heparin or aspirin is better in preventing life …
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Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT

K
Karl Shively
L
Luke A. Lopas, MD
18 years - 64 years
All genders
Phase 3
Interventional
The proposed study is a multi-center, prospective randomized controlled trial comparingurrent standard of care treatment to the SEXTANT treatment protocol in patients with Typeures of the tibia and IIIB fractures of the ankle and hindfoot.
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Distal Radius Interventions for Fracture Treatment (DRIFT)

E
Erika Daley
4 years - 10 years
All genders
Interventional
This protocol describes a multicenter, prospective randomized superiority trial comparingunctional outcomes between children treated with sedated reduction versus no formalduction.
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Voice Measures & Respiratory Kinematics in Children & Adults with & without Voice & Resonance Disorders

R
Robert Fujiki
4 years - 80 years
All genders
Observational
This study will examine laryngeal physiology and respiratory kinematics in children and adults with and without voice disorders and cleft palate.THIS STUDY IS ENROLLING BY INVITATION ONLY -  Potential participants for the patient group will be patients of the Voice and Swallow Clinics, or craniofacial anomalies clinic at IUH. Speech-Language …
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