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Found 83 Surgery trials

A listing of Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

J
Joel Corvera, MD
18 years or above
All genders
Phase 3
Interventional
The primary objective of this study is to evaluate the effectiveness (prevention ofhromboembolic events) and safety (major bleeding) of adding oral anticoagulation (OAC) to background antiplatelet therapy in patients who develop new-onset post-operative atrialbrillation (POAF) after isolated coronary artery bypass graft (CABG) surgery. All patients with a qualifying POAF event, …
S
Senthil Packiasabapathy
10 years - 17 years
All genders
Interventional
The purpose of this collaborative CTSA application is to develop an innovative perioperativegesia platform (PPAP) to improve analgesia and reduce serious immediate andg-term adverse outcomes of perioperative opioids in children undergoing painful surgery.
S
Samantha Armstrong
18 years - 100 years
All genders
Phase 3
What is the purpose of this study?This is a multicenter, randomized, open label phase lll trial to assess whether preoperative chemotherapy, as an adjunct to curative-intent surgery, improves the prognosis of high risk DDLPS (dedifferentiated Liposarcoma) and LMS (Leiomyosarcoma) patients as measured by disease free survival. Interested in participating? For more …
M
Mark Turrentine, MD
All genders
What is the purpose of this study?The purpose of this study is to participate in a registry of patients with congenital heart disease. Patient data from the United States, Canada, and South America (whose institutions of care are members of the Congenital Heart Surgeon’s Society) will be submitted to this …
18 years or above
All genders
Phase 3
Interventional
This randomized phase III trial studies how well radiation therapy works compared with observation in treating patients with newly diagnosed grade II meningioma that has been completely removed by surgery. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors.
C
Carla Fisher, MD
18 years - 100 years
All genders
Phase 1
What is the purpose of this study?This is a multicenter, first-in-human (FIH), open label, Phase 1 dose escalation and recommended Phase 2 dose (RP2D) extension trial with a primary objective to define the RP2D of SRG-514 when administered intraoperatively to patients undergoing breast-conserving cancer surgery. SRG-514 will be investigated utilizing …
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Nicole Horn, MD
B
Brian Gray, MD
8 years - 17 years
All genders
This study investigates pain control methods for children and adolescents undergoing elective laparoscopic cholecystectomy, which is a surgery to remove the gallbladder. The study will compare two methods: the transversus abdominis plane (TAP) block and local wound infiltration (LWI). Both methods utilize the same numbing medication. A TAP block involves …
G
Gulraj Singh Chawla
18 years - 80 years
All genders
Interventional
What is the purpose of this study?At Indiana University AAHC, both sufentanil and intravenous methadone are the standard of care for pain management in patients undergoing neck dissection with free flap reconstruction and both have had great success. In this study, we propose to compare their effectiveness at different post-operative …
M
Marcelino Rivera
18 years - 100 years
All genders
Interventional
What is the purpose of this study?This is a multicenter prospective trial with randomized and observational cohorts assessing patient-reported outcomes and unplanned healthcare utilization following ureteroscopic treatment of renal and ureteral stones, with placement versus omission of a ureteral stent.The study team hypothesizes that:Pain interference change from pre-surgery to Day …
N
Niharika Samala, MD
18 years - 100 years
All genders
This research aims understand the burden of sarcopenia and its association with hepatic decompensation in patients with cirrhosis caused by NAFLD, in particular post-menopausal women and compare to age matched males with and without type 2 diabetes.