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Found 83 surgery trials

A listing of surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Study on Investigational Medication for Preventing Pancreatic Fluid Leakage After Surgery

R
Ryan Ellis
18 years - 100 years
All genders
Phase 3
This study investigates the use of an investigational medication to prevent postoperative pancreatic fistula (POPF) in patients undergoing distal pancreatectomy. POPF is a complication that can occur after surgery on the pancreas, where pancreatic fluid leaks from the surgical site. The study aims to compare the incidence of POPF in …
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Congenital Heart Surgeons' Society (CHSS) Studies in Congenital Heart Disease

M
Mark Turrentine, MD
All genders
What is the purpose of this study?The purpose of this study is to participate in a registry of patients with congenital heart disease. Patient data from the United States, Canada, and South America (whose institutions of care are members of the Congenital Heart Surgeon’s Society) will be submitted to this …
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Observation or Radiation Therapy in Treating Patients With Newly Diagnosed Grade II Meningioma That Has Been Completely Removed by Surgery

18 years or above
All genders
Phase 3
Interventional
This randomized phase III trial studies how well radiation therapy works compared with observation in treating patients with newly diagnosed grade II meningioma that has been completely removed by surgery. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors.
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Study of Investigational Medication Administered During Breast-Conserving Surgery

C
Carla Fisher, MD
18 years - 100 years
All genders
Phase 1
This study investigates the safety and appropriate dosage of an investigational medication given to patients during breast-conserving surgery for breast cancer. Breast-conserving surgery involves removing the cancer while keeping as much normal breast as possible. The investigational medication is administered directly to the surgical site to assess its effects on …
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Urinary Trypsinogen-2 for Detecting Pancreatitis After Pancreas Surgery

N
Nicholas Zyromski, MD
18 years - 100 years
All genders
This study investigates the use of urinary trypsinogen-2 to detect post-pancreatectomy acute pancreatitis (PPAP). Pancreatectomy is a surgery to remove part or all of the pancreas. PPAP is a condition that can occur after this surgery, where the pancreas becomes inflamed. The purpose of this study is to see if …
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Long-term Characterization of GORE® TAG® Conformable Thoracic Stent Graft With ACTIVE CONTROL System Performance

J
Joel Corvera, MD
18 years - 100 years
All genders
Observational
An observational, prospective multi-regional post-market registry collecting mid- and long-term data to assess outcomes through ten years of follow-up for subjects treated with GORE® TAG® Conformable Thoracic Stent Graft with ACTIVE CONTROL System as a part of routine clinical practice. This post-market registry for the GORE® TAG® Conformable Thoracic Stent …
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Tranversus Abdominis Plane Block vs. Local Wound Infiltration for Elective Laparoscopic Cholcystectomy in Children and Adolescents: A Prospective Randomized-Controlled Trial

N
Nicole Horn, MD
B
Brian Gray, MD
8 years - 17 years
All genders
This study investigates pain control methods for children and adolescents undergoing elective laparoscopic cholecystectomy, which is a surgery to remove the gallbladder. The study will compare two methods: the transversus abdominis plane (TAP) block and local wound infiltration (LWI). Both methods utilize the same numbing medication. A TAP block involves …
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Genomics of Obesity and Asthma – The Role of Adipose Tissue (GenOAAT)

E
Erick Forno
6 years - 24 years
Accepts healthy volunteer
All genders
Researchers at Indiana University School of Medicine are conducting a research study to better understand how obesity makes asthma and lung function worse. Obesity and asthma are two of the most important health problems affecting adolescents and adults. In the last few years, we haveund evidence that the amount of …
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Randomized prospective study comparing sufentanil infusion vs intravenous methadone for postoperative analgesia following head and neck dissection with free flap reconstruction

G
Gulraj Singh Chawla
18 years - 80 years
All genders
Interventional
What is the purpose of this study?At Indiana University AAHC, both sufentanil and intravenous methadone are the standard of care for pain management in patients undergoing neck dissection with free flap reconstruction and both have had great success. In this study, we propose to compare their effectiveness at different post-operative …
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Stent Omission After Ureteroscopy and Lithotripsy in the Michigan Urological Surgery Improvement Collaborative (SOUL MUSIC)

M
Marcelino Rivera
18 years - 100 years
All genders
Interventional
What is the purpose of this study?This is a multicenter prospective trial with randomized and observational cohorts assessing patient-reported outcomes and unplanned healthcare utilization following ureteroscopic treatment of renal and ureteral stones, with placement versus omission of a ureteral stent.The study team hypothesizes that:Pain interference change from pre-surgery to Day …
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