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Found 20 Leukemia trials

A listing of Leukemia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome

T
Toshihiro Onishi, MD
6 - 21
All genders
Phase 3
Interventional
What is the purpose of this study?This phase III trial compares hematopoietic (stem) cell transplantation (HCT) usinghed related donors (haploidentical [haplo]) versus matched unrelated donors (MUD) ing children, adolescents, and young adults with acute leukemia or myelodysplasticyndrome (MDS). HCT is considered standard of care treatment for patients with high-riskute leukemia …
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A Phase 1/2 Multi-Center Trial of Vorinostat for Graft vs Host Disease Prevention in Children, Adolescents and Young Adults Undergoing Allogeneic Blood and Marrow Transplantation

A
April Rahrig, MD
3 - 39
All genders
Phase 1/2
Interventional
What is the purpose of this study?The purpose of this study is to determine the recommended phase 2 dose of the drug Vorinostat in children, adolescents and young adults following allogeneic blood or marrow transplant (BMT) and determine whether the addition of Vorinostat to the standard graft versus host disease …
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A Phase 2 Study of SNDX-5613 in Combination With Chemotherapy for Patients With Relapsed or Refractory KMT2A-Rearranged Infant Leukemia

A
Amanda J. Saraf, DO
1 - 6
All genders
Phase 2
What is the purpose of this study? This phase II trial tests the safety and best dose of revumenib when given together with chemotherapy, and how well the treatment regimen works for infants and young children with leukemia that has come back (relapsed) or does not respond to treatment (refractory) and …
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Children and their Caregivers Needed for Play Activities During Cancer Treatment Study

S
Sheri Robb
3 - 8
All genders
Researchers at Indiana University School of Nursing/Riley Children's Hospital are looking for children and their parents/caregivers to take part in a study to find out how play activities, like stories and music, can be used to help lower young child and caregiver stress and improve quality of life during cancer …
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T-Cell Leukemia/Lymphoma Biorepository

U
Utpal Dave, MD
100 or below
All genders
What is the purpose of this study?The purpose of this study is to collect and store specimens for future research related to T-Cell lymphoma and leukemia diagnosis and treatment.THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not actively “recruited,” but are screened by …
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A Phase 1 study of GRN163L (Imetelstat, IND# 170891, NSC# 754228) in combination with fludarabine and cytarabine for patients with acute myeloid leukemia that is in second or greater relapse or that is refractory to relapse therapy; myelodysplastic syndrome or juvenile myelomonocytic leukemia in first or greater relapse or is refractory to relapse therapy

B
Brian Weiss
1 - 18
All genders
Phase 1
What is the purpose of this study?This phase I trial tests the safety, side effects, and best dose of imetelstat in combination with fludarabine and cytarabine in treating patients with acute myeloid leukemia (AML), myelodysplastic syndrome (MDS) or juvenile myelomonocytic leukemia (JMML) that has not responded to previous treatment (refractory) …
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A Phase 2 Study of Inotuzumab Ozogamicin (NSC# 772518) in Children and Young Adults With Relapsed or Refractory CD22+ B-Acute Lymphoblastic Leukemia (B-ALL)

S
Sandeep Batra, MD
1 - 21
All genders
Phase 2
What is the purpose of this study?This phase II trial studies how well inotuzumab ozogamicin works in treating younger patients with B-lymphoblastic lymphoma or CD22 positive B acute lymphoblastic leukemia that has come back (relapsed) or does not respond to treatment (refractory). Inotuzumab ozogamicin is a monoclonal antibody, called inotuzumab, …
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A Phase II Pilot Trial to Estimate Survival After a Non-total Body Irradiation (TBI) Based Conditioning Regimen in Patients Diagnosed With B-acute Lymphoblastic Leukemia (ALL) Who Are Pre-allogeneic Hematopoietic Cell Transplantation (HCT) Next-generation-sequence (NGS) Minimal Residual Disease (MRD) Negative

J
Jodi Skiles
1 - 25
All genders
Phase 2
What is the purpose of this study?This study will evaluate the use of non-TBI (total body irradiation) conditioning for B-ALL patients with low risk of relapse as defined by absence of NGS-MRD (next generation sequencing minimal residual disease) before receiving a hematopoietic cell transplant (HCT). The primary purpose of this …
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Optimizing the design and functionality of the CLL Mind Map, an Innovative Digital Decision Aid with A Dynamic Graphical Interactive Interface

L
Larry Cripe, MD
18 - 100
All genders
What is the purpose of this study?Optimize the design and functionality of the CLL Mind Map based upon feedback of patients with CLL or related indolent non-Hodgkin s lymphomad their designated caregiver.THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not actively “recruited,” but …
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A multi-center, open-label study to determine the dose and safety of oral asciminib in pediatric patients with Philadelphia chromosome positive chronic myeloid leukemia in chronic phase (Ph+ CML-CP), previously treated with one or more tyrosine kinase inhibitors

R
Rachael Schulte
1 - 18
All genders
Phase 1/2
What is the purpose of this study?The aim of this study is to support development of asciminib in the pediatric population (1 to <18 years) with Philadelphia chromosome positive chronic myeloid leukemia in chronic phase (PH+ CML-CP) previously treated with one or more Tyrosine kinase inhibitor (TKIs). THIS STUDY IS ENROLLING …
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