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Found 154 Tumor trials
A listing of Tumor medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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Scott Coven
This study investigates the effects of two investigational medications, trametinib and everolimus, on young patients with gliomas that have returned. Gliomas are a type of brain tumor. Trametinib targets a protein in cells called MEK, which helps stop tumor growth. Everolimus blocks another pathway in tumor cells that can help …
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Jenny Belsky, DO
This study investigates the use of immunotherapy in treating Hodgkin lymphoma, a type of cancer that affects the lymphatic system. Hodgkin lymphoma is a condition where cells in the lymphatic system grow abnormally and may spread beyond it. The purpose of this study is to compare adding immunotherapy (brentuximab vedotin …
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Anthony Ross
This study investigates an investigational medication for treating Langerhans cell histiocytosis (LCH), a disease where the body makes too many immature Langerhans cells, a type of white blood cell. These cells can build up and form tumors in organs like bones, skin, and lungs, causing damage. The purpose of the …
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Jodi Skiles
This study investigates an immunotherapy treatment for children, adolescents, and young adults with high-risk T-cell acute lymphoblastic leukemia (T-ALL) or T-cell lymphoblastic lymphoma (T-LLy). The purpose of this study is to determine the safety of using an investigational medication after a procedure called total body irradiation (TBI) and a type …
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Amanda J. Saraf, DO
This study investigates the addition of investigational medication and investigational immunotherapy to the usual chemotherapy for infants with newly diagnosed acute lymphoblastic leukemia (ALL). ALL is a type of cancer where the bone marrow makes too many immature lymphocytes (a type of white blood cell). In this study, the researchers …
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Bryan Schneider, MD
What is the purpose of this study?This Phase III, randomized, open-label, multicenter study will evaluate the efficacy andy of giredestrant plus everolimus compared with the physician's choice of endocrineherapy plus everolimus in participants with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative locally advanced or metastatic breast cancer …
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Brian Weiss
This study investigates the safety and best dose of an investigational medication combined with chemotherapy drugs, fludarabine and cytarabine, for treating certain blood cancers. The cancers include acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), and juvenile myelomonocytic leukemia (JMML) that have not responded to previous treatment or have returned after …
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Sherif Farag, MD
This study is an access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs) in pediatric and adult patients with hematologic malignancies and otherdications.
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Sandeep Batra, MD
This study investigates treatment options for children and young adults with low-grade glioma (LGG), a type of brain tumor. The purpose of this study is to compare the effects of an investigational medication with standard chemotherapy treatments, carboplatin and vincristine, in patients who do not have a specific genetic mutation …
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Sandeep Batra, MD
This study investigates the safety and effects of combining an investigational medication with radiation therapy in children and young adults who have been newly diagnosed with diffuse intrinsic pontine glioma (DIPG) or high-grade glioma (HGG), which are types of brain cancers. Glioma is a cancer that occurs in the brain …
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