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Found 165 Tumor trials

A listing of Tumor medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Study on Investigational Treatment for Progressive Intracranial Meningioma

K
Kathryn Nevel
18 years - 100 years
All genders
Phase 2
This study investigates the effects of an investigational treatment for adults with progressive intracranial meningioma, which is a type of brain tumor. The study involves patients with grades 1 to 3 meningioma that has shown growth despite previous treatment.Participants will be randomly assigned to receive either the investigational treatment or …
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Investigation of Biological Targets for Pediatric Craniopharyngioma Treatment

J
Jignesh Tailor
30 days - 21 years
All genders
This study investigates pediatric adamantinomatous craniopharyngioma, a type of brain tumor. Craniopharyngioma is a condition where a non-cancerous tumor forms near the pituitary gland, which is located at the base of the brain. This study aims to identify biological targets that could lead to new medical therapies, as current treatments …
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Study Comparing Investigational Medication to Rituximab for Follicular Lymphoma

K
Khushali Jhaveri
18 years - 100 years
All genders
Phase 3
This study investigates the effectiveness of two treatments for people with a type of cancer called follicular lymphoma, which affects certain white blood cells. The purpose of this study is to compare an investigational medication with rituximab, which is a monoclonal antibody that attaches to a protein on cancer cells …
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Investigating Fear of Cancer in Women at Higher Risk of Breast Cancer

S
Shelley Johns
18 years - 100 years
Female
This study investigates the fear of cancer occurrence in women who are at a higher risk of developing breast cancer but have not been diagnosed. These women are known as 'previvors.' The purpose of this study is to create a new measure to understand their fear better. Two existing tools …
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Safety and Efficacy of Epcoritamab With Gemcitabine, Dexamethasone, and Cisplatin (GDP) Salvage Chemotherapy in Relapsed Refractory Large B-cell Lymphoma

V
Varun Mittal
18 years or above
All genders
Phase 2
Interventional
What is the purpose of this study?This is a research study being done to see if adding a drug called epcoritamab to “salvage chemotherapy” GDP (gemcitabine + cisplatin, with dexamethasone) will better treat cancer than using chemotherapy alone.  THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology …
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Testing the Addition of Chemotherapy Drug, Cisplatin, to Usual Radiation Therapy for Patients with Head and Neck Cancer

G
Greg Durm, MD
18 years - 100 years
All genders
Phase 2
Interventional
The purpose of this study is to compare two treatment approaches that are currently used after surgery for head and neck cancer. One approach is to administer radiation therapy alone. A second approach is to administer radiation therapy along with the chemotherapy drug, cisplatin.
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Study of Investigational Treatment for HER2-positive Breast Cancer

T
Tarah Ballinger, MD
18 years or above
All genders
Phase 2
Interventional
This study investigates treatments for people with HER2-positive breast cancer. HER2-positive means that the cancer cells have more HER2 protein than normal, which can cause cancer cells to grow. The study looks at using a combination of investigational medication injections and hormone therapy after surgery. The investigational medications are trastuzumab …
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Investigating Treatment Deintensification for HPV-Positive Oropharyngeal Cancer

M
Michael W. Sim, MD
18 years - 100 years
All genders
This study investigates a new approach for treating HPV-positive oropharyngeal squamous cell carcinoma (OPSCC). The purpose of this study is to see if reducing the intensity of treatment, based on levels of ctHPVDNA (pieces of cancer DNA in blood samples), can be as effective as the standard treatment. OPSCC is …
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Study on Breast Cancer Treatment with Hormone and Radiation Therapy

N
Naoyuki Saito, MD
50 years - 70 years
All genders
Phase 3
Interventional
This study investigates the treatment of breast cancer in patients who have hormone-sensitive, HER-2 negative tumors with a low recurrence score. The purpose is to understand if breast conservation surgery with only endocrine therapy is as effective as combining it with radiation therapy in preventing the return of cancer in …
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Study Comparing Shorter Treatment to Usual for Early-Stage Breast Cancer

K
Kathy Miller, MD
16 years - 100 years
All genders
Phase 3
This study investigates the effects of shorter chemotherapy-immunotherapy without anthracyclines compared to the usual treatment for early-stage triple negative breast cancer. Triple negative breast cancer is a type of breast cancer that does not have estrogen receptors, progesterone receptors, or too much of the protein called HER2. This study will …
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