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Found 165 Cancer trials

A listing of Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Evaluating a 3D Printed Oral Stent Device with Suction for Oral Cancer RT

M
Mark Langer, MD
18-100 years
All genders
A foam bite is the standard device used to hold the tongue in place during radiation treatment of cancers of the tongue. There is no device currently available to fix the tongue in place and remove oral secretions (i.e. saliva) through suction tubing attached to the stent. We wish to see …

APOLLO: A Randomized Phase II Double-Blind Study of Olaparib versus Placebo Following Curative Intent Therapy in Patients with Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation

A
Anita Turk
18-100 years
All genders
Phase 2
Interventional
The purpsoe of this study is to determine the relapse-free survival (RFS) benefit from the addition of a maintenance olaparib following completion of chemotherapy in patients with resected pancreatic carcinoma and a pathogenic germline or somatic mutation in BRCA1, BRCA2 or PALB2. Eligibility: Patient must be ≥18 years of age …

Evaluating Different Methods of Circulating Tumor DNA Quantification in Oncology Patients

T
Tim Lautenschlaeger, MD
18-100 years
Healthy Volunteer
All genders
This study aims to invent a test that can see tiny pieces from people with cancer (specifically DNA from a person’s cancer) in blood and urine better than tests that can currently be done. In the future, this test can possibly be used to find a small cancer before other …

FT576 in Subjects With Multiple Myeloma

R
Rafat Abonour, MD
18-100 years
All genders
Phase 1
Interventional
This is a Phase I dose-finding study of FT576 as monotherapy and in combination with thebody daratumumab in multiple myeloma (MM). The study will consist of a dose-escalation stage and an expansion stage.

A Randomized Phase II Window-of-opportunity Trial of Ruxolitinib in Patients with High Risk and Premalignant Breast Conditions

C
Carla Fisher, MD
18-100 years
All genders
Interventional
This study is being done in order to see how ruxolitinib changes the breast cell when administered to participants with premalignant breast conditions.

Pediatric Hepatic Malignancy International Therapeutic Trial (PHITT)

S
Sandeep Batra, MD
All genders
This trial studies how well cisplatin and combination chemotherapy works in treating children and young adults with hepatoblastoma or liver cancer after surgery.

Maintenance Oral Etoposide or Observation Following High-dose Chemo for GCT

N
Nabil Adra, MD
18-100 years
All genders
Phase 2
Interventional
This is an open label randomized phase II trial of maintenance oral etoposide vs. observationwith relapsed GCT treated with high-dose chemotherapy (HDCT) and peripheral-blood(PBSCT).

APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation

A
Anita Turk, MD
18-100 years
All genders
Phase 2
Interventional
This phase II trial investigates how well the addition of olaparib following completion ofurgery and chemotherapy works in treating patients with pancreatic cancer that has beenurgically removed (resected) and has a pathogenic mutation in BRCA1, BRCA2, or PALB2.b is an inhibitor of PARP, an enzyme that helps repair deoxyribonucleic acid …

Daily Hand-Held Vibration Therapy for the Treatment of Chemotherapy Induced Peripheral Neuropathy (CIPN): A Pilot Study

E
Erin Newton, MD
18-100 years
All genders
Interventional
The purpose of this study is to test a potential treatment for nerve damage (neuropathy) caused by chemotherapy.

TheraSphere With Durvalumab and Tremelimumab for HCC (ROWAN)

P
Paul Haste
18-100 years
All genders
Phase 2
Interventional
The objective of the ROWAN clinical study is to assess the efficacy of local tumor control in HCC patients who receive TheraSphere followed by durvalumab and tremelimumab.
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