Health Research
and Clinical Studies

All IN for Health provides a list of hundreds of active health studies happening right here in Indiana. These health studies are conducted by faculty at Indiana University, Purdue University, and the University of Notre Dame.

All IN for Health provides a list of hundreds of active health studies happening right here in Indiana. These health studies are conducted by faculty at Indiana University, Purdue University, and the University of Notre Dame.

Browse by Featured categories

Aging
Children, Families & Pregnancy
Dental
Online
Alcohol, Tobacco, and Substance Use
Alzheimer’s Disease & Dementia
Asthma,Lungs & Allergies
Bones, Muscles and Joints
Brain, Spine & Nervous System
Covid-19 & Infectious Disease
Diabetes, Heart and Blood Vessels
Digestive System (GI), Bowel & Liver
Health Mental, Behavioral Health & Developmental Conditions
Healthy Volunteer
Cancer
Diet, Nutrition, Exercise, & Sleep

Browse by Featured categories

Aging
Children, Families & Pregnancy
Dental
Online
Alcohol, Tobacco, or Other Substance Use
Alzheimer’s Disease & Dementia
Asthma,Lungs & Allergies
Bones, Muscles and Joints
Brain, Spine & Nervous System
Covid-19 & Infectious Disease
Diabetes, Heart and Blood Vessels
Digestive System (GI), Bowel & Liver
Health Mental, Behavioral Health & Developmental Conditions
Healthy Volunteer
Cancer
Diet, Nutrition, Exercise, & Sleep

Browse by Featured categories

Aging
Alcohol, Tobacco and Substance Use
Brain, Spine and Nerves
Cancer
Diabetes
Diet, Exercise and Nutrition
Healthy Volunteers
Mental and Behavioral Health
Alzheimer’s Disease and Dementia
Autoimmune Disease
Bladder and Kidneys
Bones, Muscles and Joints
Community and Environmental Health
Dental
Eye Conditions
Genetic and Rare Conditions
GI, Liver and Pancreas
Hearing, Speech and Language
Heart Health
Infectious Disease
Lungs, Asthma and Allergies
Maternal, Infant and Child Health
Online Studies
Public Health Studies
Skin and Wounds
Sleep
Surgery, Transplant and Imaging
Thyroid, Hormones and Metabolism

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Help Shape the Future of Health
with the Indiana Biobank

By donating a small blood sample, you can help researchers discover better treatments and improve health across Indiana.

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Who Can Join?

All IU Health Patients of Any Age

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What Is Involved?

It's easy-we collect a blood sample during your regular doctor visit.

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Why does it Matter?

By taking part, you're helping improve care for you, your loved ones, and people across Indiana.

Count Me IN!

Browse studies by

Recently added/updated trials

 Join Us in Advancing Alzheimer’s Research—Your Blood Sample Can Make a Difference

Join Us in Advancing Alzheimer’s Research—Your Blood Sample Can Make a Difference

T
Tatiana Foroud
50 years or above
Accepts healthy volunteer
All genders
One Blood Sample. One Visit. A Big Impact.The Indiana Biobank is a research program that began in 2010 through the Indiana University School of Medicine and IU Health. You can think of it like a huge library—only instead of storing books, it stores more than 60,000 blood and other medical samples.Each sample is linked to a person’s medical records, but names and personal details are removed before researchers ever see them. This protects privacy while still allowing doctors and scientists to learn from the information.This particular study is part of the Biobank’s special collections for Alzheimer’s research.. It focuses on gathering blood samples from three groups of people:Individuals with Alzheimer’s disease (AD),Individuals with cognitive impairment, andHealthy adults (known as “controls”)By studying these samples, scientists can make sure that Alzheimer’s-related blood tests give consistent, reliable results no matter which lab looks at them. This is an important step toward improving how we diagnose and understand Alzheimer’s disease.More information about the Indiana Biobank, as well as FAQs, can be found here:  https://iuhealth.org/find-medical-services/indiana-biobank
 Indiana Biobank – Help Shape the Future of Medicine with the Indiana Biobank!

Indiana Biobank – Help Shape the Future of Medicine with the Indiana Biobank!

T
Tatiana Foroud
100 years or below
Accepts healthy volunteer
All genders
The Indiana Biobank is a research study started in 2010 by Indiana University School of Medicine and IU Health. The Indiana Biobank is like a giant library—but instead of books, it holds over 60,000 blood and other samples. Each sample is connected to the person’s medical records. The person’s name and personal details are removed before researchers can use the samples. These samples help doctors and scientists discover better ways to treat and prevent diseases!When you donate a small blood sample, you’re helping researchers learn more about how to keep people healthy. Your sample is unique, and it can help make sure future treatments work for everyone.Watch this video to learn more: 
 The Most Important Factor in Research is YOU!  Join ResearchMatch.org

The Most Important Factor in Research is YOU! Join ResearchMatch.org

S
Sarah Wiehe, MD
100 years or below
Accepts healthy volunteer
All genders
Every medicine we take, medical device we use, and therapy we receive, was created with the help of people who took part in a research study. Their participation helped find treatments and cures to improve health outcomes. To take part, go to: ResearchMatch-Indiana CTSI
Learn More
Online study

Bowel Continence Across the Lifespan in People with Spina Bifida

K
Konrad Szymanski, MD
5 years - 100 years
All genders
Observational
The purpose of this study is to compare these two types of enema programs in children and adults with spina bifida across the United States. We want to learn about how well enemas work to prevent bowel accidents and other bowel problems, how well people can do their enemas on their own, how often people have enema problems, and the quality of life of people who use enemas.THIS STUDY IS ENROLLING BY INVITATION ONLY - This study is identifying and enrolling children age 5 and older and adults with myelomeningocele followed at pediatric and adult multidisciplinary spina bifida clinics across the United States. Eligibility will be screened through study coordinator review of the electronic medical record and/or in discussion with clinicians in the SB clinic that participants are being recruited from. Children and adults with MM who are starting a new enema program or switching from one enema program to another will be recruited and enrolled prior to initiation of the new enema program. 
 Struggling With Depression? Learn About A Study Exploring New Options For Adults Living With Treatment-Resistant Depression

Struggling With Depression? Learn About A Study Exploring New Options For Adults Living With Treatment-Resistant Depression

S
Susan Conroy, MD PhD
22 years - 70 years
All genders
Interventional
Still searching for relief from depression? Have you tried multiple treatments for depression without success? You may have another option.When treatments haven’t worked, research may offer a new path. The Abbott TRANSCEND study is a research study for adults with depression who have not felt better after trying at least four different antidepressant medications. The purpose of the study is to learn how safe and effective a treatment called deep brain stimulation (DBS) may be for people with treatment-resistant depression. DBS uses a medical device made by Abbott to deliver gentle electrical signals to specific areas of the brain. This treatment is still being studied and is not yet approved for this use.You may qualify to join this study if you:Are between the ages of 22 and 70Have been diagnosed with depression and are currently experiencing a depressive episode for at least 12 monthsHave tried at least 4 different treatments without successAre willing and able to attend regular study visits at the IU Health Neuroscience Center in Indianapolis, IN over the course of 3 years Please visit this link to complete registration to be contacted for this study: https://redcap.link/TRANSCEND

A Multicenter, Open-label, Randomized, Bupivacaine-Controlled Study to Evaluate the Pharmacokinetics and Safety of EXPAREL for Postoperative Analgesia in Subjects Aged 0 to Less Than 6 Years Undergoing Cardiac Surgery

B
Brandon Tanner
6 years or below
All genders
Phase 1
Interventional
This Phase 1, multicenter, open-label, randomized, bupivacaine-controlled study is designed to evaluate the pharmacokinetics (PK) and safety of EXPAREL vs. bupivacaine HCl for postsurgical analgesia in pediatric subjects aged 0 to less than 6 years of age undergoing cardiac surgery, utilizing local infiltration analgesia (LIA). THIS STUDY IS ENROLLING BY INVITATION ONLY - Pediatric subjects aged 0 to less than 6 years of age identified by the research team as having postsurgical analgesia undergoing cardiac surgery, utilizing local infiltration analgesia (LIA) will be invited to participate.

A Randomized Controlled, Open-Label, Rater-Blinded Pragmatic Trial, Treatment of Inflammatory Myelitis and Optic Neuritis With Early Vs Rescue Plasma Exchange (Timely-Plex)

D
Devon Mackay
18 years - 100 years
All genders
Phase 3
Interventional
The purpose of this research is to evaluate if early vs rescue Therapeutic Plasma Exchange (PLEX) treatment algorithm leads to better visual outcomes in severe Optic Neuritis and leads to better neurological disability outcomes in severe Transverse Myelitis.THIS STUDY IS ENROLLING BY INVITATION ONLY