Healthy Females Needed To Help Develop A Vaccine for Chlamydia (IMPACT Study)
Accepts healthy volunteer
Chlamydia trachomatis (CT) is the most reported bacterial sexually transmitted infection (STI) in the United States. Untreated chlamydia infection in women can result in pelvic inflammatory disease, infertility, and/or ectopic pregnancy. Although chlamydia rates are at an all-time high, no vaccine is available because we don't yet understand how immunity to chlamydia develops. The IMPACT study is a case-control study of women who are either chlamydia-naive (control group) or chlamydia-exposed (case group). The overall goal of the study is to understand how immunity develops to chlamydia so we can design a vaccine to protect women from infertility, pelvic inflammatory disease, and ectopic pregnancies. We are recruiting healthy women aged 18-40 who have never had chlamydia before to be part of the control group. You will not be exposed to chlamydia or given any vaccine; we are simply collecting blood, swabs, and genital specimens as part of the control group.This study has the potential to inform whether we should or should not be screening for gastrointestinal CT infections in women who have no symptoms, and also determine if an oral CT vaccine may be feasible in the future.