Health Research
and Clinical Studies

All IN for Health provides a list of hundreds of active health studies happening right here in Indiana. These health studies are conducted by faculty at Indiana University, Purdue University, and the University of Notre Dame.

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All IN for Health provides a list of hundreds of active health studies happening right here in Indiana. These health studies are conducted by faculty at Indiana University, Purdue University, and the University of Notre Dame.

Learn more

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Aging
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Covid-19 & Infectious Disease
Diabetes, Heart and Blood Vessels
Digestive System (GI), Bowel & Liver
Health Mental, Behavioral Health & Developmental Conditions
Healthy Volunteer
Cancer
Diet, Nutrition, Exercise, & Sleep

Browse by Featured categories

Aging
Children, Families & Pregnancy
Dental
Online
Alcohol, Tobacco, or Other Substance Use
Alzheimer’s Disease & Dementia
Asthma,Lungs & Allergies
Bones, Muscles and Joints
Brain, Spine & Nervous System
Covid-19 & Infectious Disease
Diabetes, Heart and Blood Vessels
Digestive System (GI), Bowel & Liver
Health Mental, Behavioral Health & Developmental Conditions
Healthy Volunteer
Cancer
Diet, Nutrition, Exercise, & Sleep

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Neoplasms
Surgery
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Healthy Volunteer
COVID
Diabetes Mellitus, Type 2
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Breast Cancer
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Liver Disease

I H

IN Health

W S

Will Simon

S B

Sandeep Batra, MD

C L

Craig Lammert, MD

J M

Jessica MacLean

R W

Regina Weber

K B

Kevin Bell

J M

Jean Molleston, MD

B X

Bryan Xin

G D

Greg Durm, MD

J S

Jodi Skiles

Recently added/updated trials

Denosumab for Type 1 Diabetes

C
Carmella Evans-Molina, MD
18 years - 50 years
All genders
Phase 1/2
Interventional
Researchers at City of Hope (California), University of Alabama at Birmingham, and Indiana University are studying a medication called denosumab as a potential treatment for people with type 1 diabetes. Denosumab, also known as Prolia, is a drug that has been approved by the Food and Drug Administration for bone disease treatment since 2010. This study will test if denosumab is a safe and effective treatment to help people with type 1 diabetes make insulin and improve blood sugar control.
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Healthy Volunteers Needed for MRI Brain Imaging Study

Healthy Volunteers Needed for MRI Brain Imaging Study

Q
Qiuting Wen
35 years - 60 years
Accepts healthy volunteer
All genders
Why is this study being done?The purpose of this study is to image the brain using MRI. The brain naturally changes with age, but the causes behind these changes are largely unknown. We are developing new imaging technology to early detect small changes in the brain. The goal of our study is to increase our understanding of how the brain – specifically, its CSF flow dynamic – naturally changes with age. If proven successful, the new imaging tool can help early diagnose Alzheimer’s disease.Who can take part in this study?Healthy adults, ages 35 and older older, who do not have a history of neurodegenerative disorder, chemotherapy or radiation therapy, or previous brain surgery.
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Adults Living with Heart Failure and Their Care Partners Needed for Study

Adults Living with Heart Failure and Their Care Partners Needed for Study

M
Miyeon Jung
55 years - 100 years
All genders
Study title:  Virtual reality and computerized cognitive training for mild cognitive impairment in heart failure (Vita+Com study) What is this study about?Our team examines whether viewing nature on virtual reality goggles, game-like training on an iPad, or a combination of the two can improve cognitive function (memory and thinking).  We invite people who have heart failure and concerns about their memory and thinking. Who can take part?We are enrolling participants who are ages 55 or older, with heart failure, who are having trouble with their thinking and memory.   Participants' family member, significant other, or a close friend who could best answer questions about participants' function in daily activities (e.g., cooking, driving) will co-participate in this study. 
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MRI BRAIN SURVEILLANCE ALONE VERSUS MRI SURVEILLANCE AND PROPHYLACTIC CRANIAL IRRADIATION (PCI): A RANDOMIZED PHASE III TRIAL IN SMALL-CELL LUNG CANCER (MAVERICK)

N
Naoyuki Saito, MD
18 years - 100 years
All genders
Phase 3
What is the purpose of this study?This phase III trial studies magnetic resonance imaging (MRI) surveillance and prophylactic cranial irradiation (PCI) to see how well they work compared to MRI surveillance alone in treating patients with small cell lung cancer. MRI scans are used to monitor the possible spread of the cancer with an MRI machine over time. PCI is radiation therapy that is delivered to the brain in hopes of preventing spread of cancer into the brain. The use of brain MRI alone may reduce side effects of receiving PCI and prolong patients' lifespan. Monitoring with MRI scans alone (delaying radiation until the actual spread of the cancer) may be at least as good as the combination of PCI with MRI scans.THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not actively “recruited,” but are screened by their physician for appropriate clinical trial(s) at the time of their routine clinic visit. Occasionally, a patient may be a self-referral or physician referral, but are still screened for appropriate clinical trials at the time of their routine clinic visit. PI and staff may send copies of relevant consent forms to these patients to look over prior to actually consenting or enrolling them. This may take place at the patient's visit at which the consent is presented or the patient's next visit to the outpatient hematology/oncology clinic.  Interested in participating? For more information about this research study or other cancer-related clinical trials at IU Simon Comprehensive Cancer Center, please contact:IU Clinical Trials Office Email: iutrials@iu.edu Phone: (317) 278-5632
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Immune Mechanisms of Hypertension and Cardiovascular Disease

Immune Mechanisms of Hypertension and Cardiovascular Disease

M
Meena Madhur
18 years - 85 years
Accepts healthy volunteer
All genders
Why is this study being done?The Division of Clinical Pharmacology at Indiana University is looking for volunteers with and without high blood pressure to participate in a research study to better understand how the immune system regulates blood pressure and cardiovascular disease.  This study will look at the differences in cells and chemicals in the blood between people who have high blood pressure with or without heart disease and people who have normal blood pressure. We want to know if there are cells or chemicals in the blood that may help us understand why some people develop high blood pressure.   The study is being conducted by Dr. Meena Madhur andhe Department of Medicine, Division of Clinical Pharmacology at Indiana University. It is funded by the National Institutes of Health and internal funding. Who can take part?Individuals, ages 18-85, who have normal blood pressure OR  have high blood pressure.
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DO YOU HAVE APHASIA? Join our language training study!

DO YOU HAVE APHASIA? Join our language training study!

J
Jiyeon Lee
21 years - 85 years
All genders
The Purdue Aphasia Research Lab is inviting people with aphasia after a stroke to take part in a language training study.  In this NIH-funded project, our goal is to develop a novel treatment for persons with aphasia to help them communicate more effectively.  Eligible participants will practice reading and speaking sentences. Study duration will last approximately 2-3 months.   Aphasia is an acquired language disorder, frequently caused by a stroke, that can affect speaking, understanding others, reading and/or writing.  
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Online study
Attention in Aphasia Study

Attention in Aphasia Study

A
Arianna LaCroix
18 years - 100 years
All genders
Why is this study being done?Researchers at Purdue University are recruiting for a study that examines how thinking and language change after having a stroke or other brain injury. We are investigating how different types of attention contribute to producing and understanding sentences.  Who can take part?Adults (ages 18 or older) who have aphasia following a stroke or other brain injury (TBI, viral infection, tumor, etc.)
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