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Found 105 will-simon trials

A listing of will-simon medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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J
James Croop, MD, PhD
1 years - 21 years
All genders
This study is designed to investigate whether the use of copanlisib is safe, feasible and beneficial to pediatric patients with solid solid tumors or lymphoma that are recurrent or refractory to standard therapy.
 The Susan G Komen Tissue Bank at the IU Simon Cancer Center A Collection and Storage of Biological Specimens Intended for use in the Elucidation of Breast Carcinogenesis
M
Michele Cote
18 years - 100 years
Accepts healthy volunteer
All genders
Would you like to contribute to the fight against breast cancer?  You can help by donating a breast tissue sample during an event at the IU Melvin and Bren Comprehensive Cancer Center from 8 am to 2 pm on October 19th, 2024.  While the donation process takes only 60-90 minutes, …
C
Catherine Sears, MD
18 years - 100 years
Accepts healthy volunteer
All genders
This study investigates the DNA repair capacity (DRC) in lung disease. DRC is a measure of how well cells can fix damage to their DNA. High DNA damage is often found in lung diseases like lung cancer and chronic obstructive lung disease (COPD), which includes emphysema and chronic bronchitis. The …
G
Greg Durm, MD
18 years - 100 years
All genders
Phase 2
Interventional
The purpose of this study is to compare two treatment approaches that are currently used after surgery for head and neck cancer. One approach is to administer radiation therapy alone. A second approach is to administer radiation therapy along with the chemotherapy drug, cisplatin.
A
Anita Turk, MD
18 years or above
All genders
Phase 2
Interventional
This study investigates the use of an investigational medication along with a targeted therapy called olaparib for patients with metastatic pancreatic cancer. Metastatic pancreatic cancer is when the cancer has spread from the pancreas to other parts of the body. The study focuses on patients with specific genetic mutations called …
L
Lisa Landrum, MD, PhD, MS
18 years or above
Female
Phase 3
Interventional
This study investigates treatments for women with platinum-resistant epithelial ovarian cancer, which is a type of cancer that does not respond to platinum-based chemotherapy. The purpose is to compare the effects of different treatments, including an investigational medication called nemvaleukin, either alone or in combination with another treatment, pembrolizumab, against …
B
Bryan Schneider, MD
18 years or above
All genders
Phase 2
Interventional
This study investigates treatments for patients with residual triple negative breast cancer, a type of breast cancer that does not have estrogen, progesterone, or HER2 receptors. The study uses circulating tumor DNA (ctDNA) to assign participants to different treatment arms based on their genomic markers. Participants with ctDNA positivity and …
T
Tarah Ballinger, MD
18 years or above
All genders
Phase 2
Interventional
This study investigates treatments for people with HER2-positive breast cancer. HER2-positive means that the cancer cells have more HER2 protein than normal, which can cause cancer cells to grow. The study looks at using a combination of investigational medication injections and hormone therapy after surgery. The investigational medications are trastuzumab …
N
Naoyuki Saito, MD
50 years - 70 years
All genders
Phase 3
Interventional
This study investigates the treatment of breast cancer in patients who have hormone-sensitive, HER-2 negative tumors with a low recurrence score. The purpose is to understand if breast conservation surgery with only endocrine therapy is as effective as combining it with radiation therapy in preventing the return of cancer in …
N
Nabil Adra, MD
18 years or above
All genders
Phase 2
Interventional
This study investigates maintenance treatment with oral etoposide or observation in patients with relapsed germ cell tumors (GCT) who have received high-dose chemotherapy and peripheral blood stem cell transplant. Germ cell tumors are a type of cancer that begins in the cells that give rise to sperm or eggs. This …
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