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Found 128 will-simon trials

A listing of will-simon medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Testicular Tissue Cryopreservation for Fertility Preservation

A
Amanda J. Saraf, DO
100 years or below
Male
Observational
What is the purpose of this study?Testicular tissue cryopreservation is an experimental procedure where a young boy's testicular tissue is retrieved and frozen. This technique is reserved for young male patients who are not yet producing mature sperm, with the ultimate goal that their tissue may be used in the …
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Prospective Validation of a Points Score System Predicting 30-day Survival

N
Naoyuki Saito, MD
18 years or above
All genders
Phase 2
Observational
What is the purpose of this study?This is a one-stage single-arm phase II clinical trial designed to prospectively test the survival prediction tool as developed by Lee et al on patients referred to radiation oncologyve treatments. Survival prediction score based on objective data includingboratory values, attendance to emergency room, and …
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A PHASE III TRIAL OF THE IMPACT OF SENTINEL LYMPH NODE MAPPING ON PATIENT REPORTED LOWER EXTREMITY LIMB DYSFUNCTION IN ENDOMETRIAL CANCER

L
Lisa Landrum, MD, PhD, MS
18 years - 100 years
Female
Phase 3
This phase III trial compares the effect of sentinel lymph node mapping to standard lymph node dissection in reducing the risk of swelling in the legs (lymphedema) in patients undergoing a hysterectomy for stage I endometrial cancer. Standard lymph node dissection removes lymph nodes around the uterus during a hysterectomy …
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Development of a Genetic Algorithm to Predict Anthracycline-Induced Cardiomyopathy in Adult Patients

T
Todd Skaar
18 years - 100 years
All genders
What is the purpose of this study?The purpose of this prospective study is to assess the accuracy of four previously-studied genetic variations to predict the development of cardiomyopathy (i.e., a disease of the heart muscle that reduces the ability of your heart to pump blood to your body) in adult …
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Study Comparing Shorter Treatment to Usual for Early-Stage Breast Cancer

K
Kathy Miller, MD
16 years - 100 years
All genders
Phase 3
This study investigates the effects of shorter chemotherapy-immunotherapy without anthracyclines compared to the usual treatment for early-stage triple negative breast cancer. Triple negative breast cancer is a type of breast cancer that does not have estrogen receptors, progesterone receptors, or too much of the protein called HER2. This study will …
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Study on Monitoring Symptoms During Cancer Treatment Using Surveys

J
Jordan Holmes
18 years - 100 years
All genders
This study investigates how completing surveys about symptoms and quality of life during radiation treatment affects symptom management. The focus is on patients who speak English or Spanish and are undergoing treatment for certain cancers, like endometrial, cervical, or prostate cancer. The goal is to see if real-time feedback can …
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Evaluating Different Methods of Circulating Tumor DNA Quantification in Oncology Patients

T
Tim Lautenschlaeger, MD
18 years - 100 years
Accepts healthy volunteer
All genders
What is the purpose of this study?This study aims to invent a test that can see tiny pieces from people with cancer (specifically DNA from a person’s cancer) in blood and urine better than tests that can currently be done. In the future, this test can possibly be used to …
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National Liver Cancer Screening Trial (TRACER)

N
Naga Chalasani, MD
18 years - 85 years
All genders
What is this study about?The National Liver Cancer Screening Trial is an adaptive randomized phase IV Trial comparing ultrasound-based versus biomarker-based screening in 5500 patients with cirrhosis from any etiology or patients with chronic hepatitis B infection. Eligible patients will be randomized in a 1:1 fashion to Arm A using …
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Rapid Autopsy Protocol for Patients with Small Cell Lung Cancer

S
Shadia Jalal, MD
18 years - 100 years
All genders
What is the purpose of this study?This is pilot study to establish a rapid autopsy program in Small Cell Lung Cancer (SCLC) at the Indiana University Simon Comprehensive Cancer Center and outline the components necessary for tumor tissue collection. This proposal is a collaboration between scientists, lung cancer physicians, pathologists, …
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Study on Therapy Reduction in Early-stage Triple-negative Breast Cancer

N
Nawal Kassem
18 years - 100 years
All genders
Phase 3
This study investigates the effects of continuing pembrolizumab treatment versus observation in patients with early-stage triple-negative breast cancer (TNBC) who have achieved a pathologic complete response (pCR) after receiving chemotherapy and pembrolizumab before surgery. Triple-negative breast cancer is a type of cancer that lacks three common receptors known to fuel …
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