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Found 163 will-simon trials

A listing of will-simon medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

R
Rohan Maniar
18 years and older
All genders
Phase 1/2
Interventional
What is the purpose of this study?Part 1: A first-in-human, open-label, Phase I dose escalation study of DSP107 monotherapy and combination therapy with atezolizumab in patients with advanced solid tumors. Part 2: Preliminary efficacy assessment of DSP107 in combination with atezolizumab in second or third line treatment of non small …
S
Suparna C. Clasen, MD, MSCE
40 years and older
Male
Interventional
What is the purpose of this study?This is a randomized pilot study of Coronary CT Angiography (CCTA) for coronary atherosclerosis vs. Usual Care in patients with prostate cancer who are either planning to begin, or are currently taking androgen deprivation therapy (ADT) .THIS STUDY IS ENROLLING BY INVITATION ONLY - …
V
Varun Mittal
18 years and older
All genders
Phase 2
Interventional
What is the purpose of this study?This is a research study being done to see if adding a drug called epcoritamab to “salvage chemotherapy” GDP (gemcitabine + cisplatin, with dexamethasone) will better treat cancer than using chemotherapy alone.  THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology …
A
April Rahrig, MD
3-39 years
All genders
Phase 1/2
Interventional
What is the purpose of this study?The purpose of this study is to determine the recommended phase 2 dose of the drug Vorinostat in children, adolescents and young adults following allogeneic blood or marrow transplant (BMT) and determine whether the addition of Vorinostat to the standard graft versus host disease …
L
Lisa Landrum, MD, PhD, MS
18 years and older
Female
Phase 3
Interventional
What is the purpose of this study?This is a Phase 3, multicenter, open-label, randomized study of nemvaleukin in combination with pembrolizumab versus protocol-specific Investigator's choice chemotherapy in patients with platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal cancer.THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, …
G
Greg Durm, MD
18-100 years
All genders
Phase 2
Interventional
What is the purpose of this study?This phase II trial studies the effects of temozolomide and atezolizumab as second or thirdwith small cell lung cancer that has spread to other places inhe body (metastatic) or has come back (recurrent). Chemotherapy drugs, such as temozolomide, work in different ways to stop …
T
Tarah Ballinger, MD
18 years and older
All genders
Phase 2
Interventional
What is the purpose of this study?This research study is studying a combination of HER2-directed therapies (trastuzumab anduzumab) and hormonal therapy as a treatment after surgery for hormone receptor positive breast cancer. The study drugs involved in this study are: A combination of trastuzumab and pertuzumab given as an injection …
N
Naoyuki Saito, MD
50-70 years
All genders
Phase 3
Interventional
What is the purpose of this study?This Phase III Trial evaluates whether breast conservation surgery and endocrine therapyults in a non-inferior rate of invasive or non-invasive ipsilateral breast tumorurrence (IBTR) compared to breast conservation with breast radiation and endocrineherapy.THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology …
J
Jessica Parker Metter
18-100 years
Female
Phase 3
Interventional
What is the purpose of this study?The OnPrime study is a multi-center, randomized open-label phase 3 study evaluating the safety and efficacy of Olvi-Vec followed by platinum-doublet chemotherapy and bevacizumab compared to the Active Comparator Arm with Physician's Choice of chemotherapy and bevacizumab in women diagnosed with platinum-resistant/refractory ovarian cancer …
 The Susan G Komen Tissue Bank at the IU Simon Cancer Center A Collection and Storage of Biological Specimens Intended for use in the Elucidation of Breast Carcinogenesis
M
Michele Cote
18-100 years
Accepts healthy volunteer
All genders
Would you like to contribute to the fight against breast cancer?  You can help by donating a breast tissue sample during an event at the IU Melvin and Bren Comprehensive Cancer Center from 8 am to 2 pm on October 19th, 2024.  While the donation process takes only 60-90 minutes, …
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