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Found 128 will-simon trials

A listing of will-simon medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Research Study on Safety and Effects of an Investigational Medication for Advanced Solid Tumors

M
Mateusz Opyrchal, MD, PhD
18 years - 100 years
All genders
Phase 1/2
This study investigates the safety and effects of an investigational medication in people with advanced solid tumors. Advanced solid tumors are cancers that have spread and do not respond well to regular treatments. The purpose of this study is to find out how safe the medication is, how the body …
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MODERN: An Integrated Phase 2/3 and Phase 3 Trial of MRD-Based Optimization of ADjuvant ThErapy in URothelial CaNcer

T
Tareq Salous
18 years - 100 years
All genders
Phase 2/3
What is this study about?This phase II/III trial examines whether patients who have undergone surgical removal of bladder, but require an additional treatment called immunotherapy to help prevent their bladder cancer from coming back, can be identified by a blood test. Many types of tumors tend to lose cells or …
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Study on Investigational Treatment for a Type of Cancer Affecting Plasma Cells

A
Attaya Suvannasankha, MD
18 years - 95 years
All genders
This study investigates a treatment for multiple myeloma, a type of cancer that affects plasma cells in the bone marrow. The purpose of the study is to see if the investigational treatment can improve cancer outcomes and bone health.Participants will have standard clinical assessments, such as blood draws and bone …
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Investigating Barriers to Exercise in Women with Metastatic Breast Cancer

T
Tarah Ballinger, MD
18 years - 100 years
Female
This study investigates why women with metastatic breast cancer choose not to participate in exercise programs designed for their needs. Metastatic breast cancer is when cancer has spread beyond the breast to other parts of the body. Understanding the reasons for non-participation can help improve future program designs.Participants will complete …
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Randomized prospective study comparing intrathecal morphine vs intravenous methadone for postoperative analgesia following retroperitoneal lymph node dissection (RPLND)

G
Gulraj Singh Chawla
18 years - 80 years
Male
What is the purpose of this study?At Indiana University Adult Academic Health Center (AAHC), both intrathecal morphine and intravenous methadone are the standard of care for pain management in patients undergoing retroperitoneal lymph node dissections for primary testicular cancer, and both have had great success.  In this study, we propose …
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Evaluating Disparities in Precision Oncology: An Observational Trial in the context of a Real-World Academic Practice Model (EDPO)

B
Bryan Schneider, MD
18 years or above
All genders
Observational
What is the purpose of this study?This is a non-randomized observational trial designed to collect detailed clinical, social determinant, and genomic data from patients enrolled in molecular oncology tumor boards across four comprehensive cancer centers.THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not …
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Osteosarcoma Predisposition - Developing New Models to Study Pediatric Osteosarcoma Development

J
Jennifer Ivanovich
18 years or below
All genders
What is the purpose of this study?In partnership with Indiana Biosciences Research Institute, we will develop new models to study pediatric osteosarcoma. We will invite children with Li-Fraumeni syndrome, hereditary retinoblastoma syndrome, or Rothmund-Thompson syndrome to participate. These three syndromes are associated with an increased risk to develop osteosarcoma. THIS STUDY …
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Effect of the HCC-EduLink Intervention

L
Lauren Nephew
18 years - 100 years
All genders
The objective of this study is to pilot test a multi-level intervention designed to address patient- and system-level social and structural determinants of health (SSDOH) variables and facilitate access to curative hepatocellular carcinoma (HCC) therapies, including liver transplantation and resection, in a cohort of Black patients with Barcelona Clinic Liver …
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Phase 1 Imaging Study of 68Ga-R10602 in Hormone Receptor-Positive Breast Cancer

K
Kathy Miller, MD
18 years - 100 years
All genders
Phase 1
What is the purpose of this study?This trial studies how well 68-Ga RM2 works with PET/MRI in imaging patients with estrogen receptor-positive breast cancer. 68-Ga-RM2 is an agent used in diagnostic imaging.Primary: To describe the safety of 68Ga-R10602.Secondary - To describe the biodistribution of 68Ga-R10602 in Study Participants with hormone …
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Molecular and Pathological Correlates of Treatment Outcome in Patients with Thymoma and Thymic Carcinoma

P
Patrick Loehrer, MD
1 years - 100 years
All genders
What is this study about?The major purpose of this research study is to obtain blood samples from child and adult patients diagnosed with thymoma and/or tissue samples from patients undergoing surgery for their thymoma.  We will use these specimens to test for certain characteristics that we think will be useful …
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