A listing of will-simon medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This study investigates maintenance treatment with oral etoposide or observation in patients with relapsed germ cell tumors (GCT) who have received high-dose chemotherapy and peripheral blood stem cell transplant. Germ cell tumors are a type of cancer that begins in the cells that give rise to sperm or eggs. This …
This study investigates the use of circulating tumor DNA (ctDNA) to personalize treatment for patients with stage III non-small cell lung cancer (NSCLC). The purpose is to use ctDNA analysis to guide therapy decisions, instead of relying solely on clinical or radiographic evidence of disease. This approach aims to tailor …
What is the purpose of this study?The main aim of this study is to learn whether vedolizumab and upadacitinib given together (also called dual targeted therapy or DTT) reduces bowel inflammation and ulcers in the bowel compared to vedolizumab only (also called monotherapy) in adults with moderately or severely active …
This study investigates the effects of an investigational medication alone compared to the same medication combined with tocilizumab in patients with advanced breast cancer. Advanced breast cancer includes conditions such as metastatic triple negative or ER-low breast cancer. This study involves Black and non-Black patients and aims to understand how …
This study investigates the use of abatacept in patients who have myocarditis, a heart condition, after being treated with immune checkpoint inhibitors (ICI). The purpose is to see if abatacept can lower the risk of major adverse cardiac events (MACE), which include serious heart problems like heart attacks or heart …
This study investigates treatments for people with HER2-positive breast cancer. HER2-positive means that the cancer cells have more HER2 protein than normal, which can cause cancer cells to grow. The study looks at using a combination of investigational medication injections and hormone therapy after surgery. The investigational medications are trastuzumab …
What is the purpose of this study?The OnPrime study is a multi-center, randomized open-label phase 3 study evaluating the safety and efficacy of Olvi-Vec followed by platinum-doublet chemotherapy and bevacizumab compared to the Active Comparator Arm with Physician's Choice of chemotherapy and bevacizumab in women diagnosed with platinum-resistant/refractory ovarian cancer …
We are conducting a study on adults and children with cancer diagnoses to complete a survey about describing cancer survivorship. This biennial survey study is a part of ongoing efforts Indiana University Simon Comprehensive Cancer Center (IUSCCC) and the Office of Community (COE) to better understand our cancer center’s catchment …
Would you like to contribute to the fight against breast cancer? You can help by donating a breast tissue sample during an event at the IU Melvin and Bren Comprehensive Cancer Center from 8 am to 2 pm on October 19th, 2024. While the donation process takes only 60-90 minutes, …
What is the purpose of this study?Our goals of the study include (1) Evaluating whether we can identify “at-risk” patients with localized prostate cancer who have positive germline mutations not previously known, (2) Identifying which, if any, specific pre-identified “at-risk” population groups are individually at an increased risk of carrying …
