Search
Filters
Clear All
  • 13
  • 17
  • 88

Phase

  • 9
  • 5
  • 20
  • 2
  • 25
  • 1
  • 56
  • 117
  • 15

Found 118 will-simon trials

A listing of will-simon medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Rapid Autopsy Protocol for Patients with Small Cell Lung Cancer

S
Shadia Jalal, MD
18 years - 100 years
All genders
What is the purpose of this study?This is pilot study to establish a rapid autopsy program in Small Cell Lung Cancer (SCLC) at the Indiana University Simon Comprehensive Cancer Center and outline the components necessary for tumor tissue collection. This proposal is a collaboration between scientists, lung cancer physicians, pathologists, …
Learn More

Study on Therapy Reduction in Early-stage Triple-negative Breast Cancer

N
Nawal Kassem
18 years - 100 years
All genders
Phase 3
This study investigates the effects of continuing pembrolizumab treatment versus observation in patients with early-stage triple-negative breast cancer (TNBC) who have achieved a pathologic complete response (pCR) after receiving chemotherapy and pembrolizumab before surgery. Triple-negative breast cancer is a type of cancer that lacks three common receptors known to fuel …
Learn More

Study on Chemotherapy and Hormone Therapy for Breast Cancer

T
Tarah Ballinger, MD
18 years - 60 years
Female
Phase 3
This study investigates whether adding chemotherapy to ovarian function suppression and hormone therapy improves breast cancer-free survival in premenopausal women. The focus is on those with early-stage breast cancer that is estrogen receptor-positive and HER2-negative. The study will compare outcomes between those receiving chemotherapy in addition to hormone treatments and …
Learn More

Investigating Chemoradiation (Combination of Chemotherapy and Radiation Therapy) for Early Stage Vulvar Cancer

S
Sharon E. Robertson
18 years - 100 years
Female
Phase 2
This study investigates the safety of using chemoradiation instead of surgery for early stage vulvar cancer. Vulvar cancer is a type of cancer that affects the external female genitalia. In some cases, cancer spreads to nearby lymph nodes. This study looks at patients with a macrometastasis, which means the cancer …
Learn More

Investigating Treatment Completion in Breast Cancer Patients

T
Tarah Ballinger, MD
18 years - 100 years
Female
This study investigates how genetic ancestry affects the completion of treatment in patients diagnosed with breast cancer. Breast cancer is a disease where cells in the breast grow out of control. This study involves newly diagnosed women with stages I-III breast cancer who self-report as Black or White.Participants will provide …
Learn More

Investigating Methods to Increase Genetic Testing for Cancer Risk in Black Families

N
Nawal Kassem
18 years - 100 years
All genders
This study investigates how to increase genetic testing in Black families with hereditary cancer syndromes. Hereditary cancer syndromes are conditions where gene changes increase the risk of cancer in families. The study focuses on Black patients who have been advised to undergo genetic testing. It aims to see if using …
Learn More

Investigating Treatment Deintensification for HPV-Positive Oropharyngeal Cancer

M
Michael W. Sim, MD
18 years - 100 years
All genders
This study investigates a new approach for treating HPV-positive oropharyngeal squamous cell carcinoma (OPSCC). The purpose of this study is to see if reducing the intensity of treatment, based on levels of ctHPVDNA (pieces of cancer DNA in blood samples), can be as effective as the standard treatment. OPSCC is …
Learn More

Study of Imaging and Treatment Agents for Breast Cancer

K
Kathy Miller, MD
18 years - 100 years
All genders
Phase 1
This study investigates how safe and effective two investigational agents, an imaging agent and a therapeutic agent, are for patients with advanced breast cancer. The imaging agent, called 68Ga-R11228, is used to locate specific tumor cells in the body. The therapeutic agent, 177Lu-R11228, is used for treatment. Both agents are …
Learn More

Study Comparing Investigational Medication to Rituximab for Follicular Lymphoma

K
Khushali Jhaveri
18 years - 100 years
All genders
Phase 3
This study investigates the effectiveness of two treatments for people with a type of cancer called follicular lymphoma, which affects certain white blood cells. The purpose of this study is to compare an investigational medication with rituximab, which is a monoclonal antibody that attaches to a protein on cancer cells …
Learn More

Breast Cancer Treatment Monitoring Study

T
Tarah Ballinger, MD
18 years - 100 years
Female
This study investigates the use of the NearWave optical molecular monitoring system to track the progress of breast cancer treatment. The purpose is to see if this system can predict how well patients respond to chemotherapy before surgery. Breast cancer is a disease where cells in the breast grow uncontrollably. …
Learn More
51 - 60 of 118