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Found 113 will-simon trials

A listing of will-simon medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

A
Anita Turk, MD
18 years - 100 years
All genders
Phase 4
This study investigates the effects of an investigational medication on high blood pressure in patients with refractory metastatic colorectal cancer (mCRC) from minority groups, specifically Black/African American and Hispanic/Latino populations. High blood pressure, also known as hypertension, is when the force of blood against the artery walls is too high, …
G
Greg Durm, MD
18 years - 100 years
All genders
Phase 1
This study investigates the safety and effects of an investigational antibody-drug conjugate in patients with advanced or metastatic solid tumors. The purpose is to understand how the investigational medication works in the body and its impact on tumors. Advanced or metastatic solid tumors are cancers that have spread beyond their …
J
Jessica Parker
18 years - 100 years
Female
Phase 3
This study investigates the effectiveness of an investigational medication in combination with another medication compared to the other medication alone as a first-line maintenance therapy for patients with HER2-expressing ovarian cancer. HER2 is a protein that can affect the growth of some cancer cells. This study focuses on advanced high-grade …
N
Nabil Adra, MD
18 years - 100 years
Male
Phase 2/3
This study investigates the treatment of PSMA-positive metastatic castration-resistant prostate cancer (mCRPC) using an investigational medication called AAA817. The purpose of this study is to compare the effects of AAA817 with the standard of care treatment in adults who have already been treated with certain cancer therapies but have not …
S
Sharon E. Robertson
18 years - 100 years
Female
Phase 4
This study investigates the effects of an investigational medication on eye health in patients with recurrent or metastatic cervical cancer. Cervical cancer occurs when cells in the cervix grow uncontrollably. This study focuses on understanding any side effects related to the eyes that may arise from the treatment. A side …
T
Tareq Salous
18 years - 100 years
All genders
Phase 3
This study investigates how well an investigational medication combination works in treating adults with untreated locally advanced or metastatic urothelial carcinoma with an FGFR3 genetic alteration. Urothelial carcinoma is a type of cancer that occurs in the urinary system. This study uses a combination of medications, including monoclonal antibodies, which …
C
Cindy Yuan
18 years - 100 years
All genders
Phase 1
This study investigates the use of an investigational imaging substance in people with advanced solid tumors. The purpose is to understand how safe this substance is and how well it works in taking pictures of tumors inside the body. It will compare these pictures to the ones taken with regular …
P
Patrick Loehrer, MD
1 years - 100 years
All genders
What is this study about?The major purpose of this research study is to obtain blood samples from child and adult patients diagnosed with thymoma and/or tissue samples from patients undergoing surgery for their thymoma.  We will use these specimens to test for certain characteristics that we think will be useful …
A
Anna Maria Storniolo, MD
110 years or below
All genders
What is the purpose of this study?Adult patients (18 years of age and older) and pediatric patients (younger than 18 years of age) who are being evaluated for and/or treated for cancer at the NIH Clinical Center and at participating sites will be entered onto this tissue procurement protocol for …
G
Greg Durm, MD
18 years - 100 years
All genders
Phase 2
Interventional
The purpose of this study is to compare two treatment approaches that are currently used after surgery for head and neck cancer. One approach is to administer radiation therapy alone. A second approach is to administer radiation therapy along with the chemotherapy drug, cisplatin.
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