A listing of will-simon medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This study investigates how to increase genetic testing in Black families with hereditary cancer syndromes. Hereditary cancer syndromes are conditions where gene changes increase the risk of cancer in families. The study focuses on Black patients who have been advised to undergo genetic testing. It aims to see if using …
What is the purpose of this study?People with Oropharyngeal squamous cell carcinoma (OPSCC) typically receive standard treatment with a combination of chemotherapy, radiation therapy, and surgery. Due to the intensity of standard treatment, survivors may experience unwanted long-term side effects. The goal of this research study is to see if …
Researchers as the Indiana University Simon Comprehensive Cancer Center are conducting a study to research the safety and effectiveness of increasing doses of CD4CAR T cell therapy for patients who have been diagnosed with, or are being treated for, relapsed or refractory (has not responded to treatment) CD4+ chronic myelomonocytic …
The purpose of this study is to evaluate an investigational system using clinical blood samples. This study investigates its performance by comparing results from the investigational system to established methods. The study involves three arms: Method Comparison, Whole Blood Precision, and WBC Flagging. Method Comparison assesses how closely the investigational …
What is the purpose of this study?The purpose of this study is to assess the feasibility of the NearWave optical molecular monitoring system for monitoring therapy progression and predicting pathologic complete response (pCR) of breast cancer patients undergoing neoadjuvant chemotherapy (NAC). THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with …
What is the purpose of this study?To characterize the way in which oncologists, oncology nurses, and oncology pharmacists evaluate the treatment options for patients with CLL/SLL and engage or support patients in shared decision-making.To test the acceptability and usability of the interactive web-enabled communication and decision-making resources of the CLL/SLL …
What is the purpose of this study?Phase 1a Dose Escalation/Cohort Expansion BBO-10203 Monotherapy Primary: To evaluate the safety and tolerability of BBO-10203, an inhibitor of the PI3Kα:RAS interaction, in subjects with locally advanced unresectable or metastatic (ie, advanced) HER2-positive BC; HR-positive, HER2-negative BC; KRAS mutant NSCLC; and KRAS mutant CRC. Secondary: To evaluate …
What is the purpose of this study?The purpose of this study is to evaluate the tolerability and toxicity of combining two radiation therapy methods. Elective Pelvic Ultra Hypofractionated Irradiation Treatment (ePUHRT), which is an external beam radiotherapy with High Dose Rate Brachytherapy Boost (form of internal radiation where a cancer …
What is the purpose of this study?In this 3-phase pilot, we will identify adverse health outcomes and unmet support needs of testicular cancer survivors (TCS) (Phase 1) and employ participatory co-design to adapt an existing acceptance and commitment therapy (ACT)-based intervention with a sample of up to 8 TCS (Phase …
This study investigates the use of an investigational device for men who have stress urinary incontinence after having their prostate removed because of cancer. Stress urinary incontinence happens when activities like coughing or lifting cause urine to leak. The purpose of this study is to see if the device is …
