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Found 107 will-simon trials
A listing of will-simon medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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Mateusz Opyrchal, MD, PhD
What is the purpose of this study?The purpose of this study is to create models out of tissue samples and treat those models with the same immunotherapy treatment the patient will be receiving, in order to validatehis process and to predict responses to therapies and use it to choose the …
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Hristos Kaimakliotis, MD
This is a prospective, multi-center, single arm study focused on data and sample collection from participants diagnosed with Stage I to IV cancers and for whom standard of care Natera MRDtesting has been ordered (for example, SignateraTM, SignateraTM Genome, or LatitudeTM). This study will utilize study sites located within the …
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Jennifer Ivanovich
What is the purpose of this study?In partnership with Indiana Biosciences Research Institute, we will develop new models to study pediatric osteosarcoma. We will invite children with Li-Fraumeni syndrome, hereditary retinoblastoma syndrome, or Rothmund-Thompson syndrome to participate. These three syndromes are associated with an increased risk to develop osteosarcoma. THIS STUDY …
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Mateusz Opyrchal, MD, PhD
What is the purpose of this study?Phase 1a Dose Escalation/Cohort Expansion BBO-10203 Monotherapy Primary: To evaluate the safety and tolerability of BBO-10203, an inhibitor of the PI3Kα:RAS interaction, in subjects with locally advanced unresectable or metastatic (ie, advanced) HER2-positive BC; HR-positive, HER2-negative BC; KRAS mutant NSCLC; and KRAS mutant CRC. Secondary: To evaluate …
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Timothy Masterson
This study investigates two different surgical techniques for treating testis cancer, focusing on retroperitoneal lymph node dissection (RPLND). The study compares the transperitoneal (TP) and extraperitoneal (EP) approaches. RPLND is a surgery to remove lymph nodes from the back of the abdomen. The purpose is to see if the EP …
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Gulraj Singh Chawla
This study investigates pain management methods for patients undergoing surgery for testicular cancer. The purpose of this study is to compare the effectiveness of two pain relief methods: intrathecal morphine (an injection into the spine) and intravenous methadone (a pain medicine given through a vein).Participants will be assigned by chance …
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Varun Mittal
This study investigates the safety and effectiveness of combining an investigational medication with a chemotherapy regimen in patients who have relapsed large B-cell lymphoma. Large B-cell lymphoma is a type of cancer that affects the lymphatic system, which is part of the body's immune system. The study aims to understand …
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Shelley Johns
This study investigates the fear of cancer occurrence in women who are at a higher risk of developing breast cancer but have not been diagnosed. These women are known as 'previvors.' The purpose of this study is to create a new measure to understand their fear better. Two existing tools …
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Catherine Sears, MD
What is the purpose of this study?This study evaluates the how addition of the Nodify XL2 test result impacts the clinicalgement of newly identified solid lung nodules assessed as low to moderate risk of cancer.THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not …
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Rafat Abonour, MD
What is the purpose of this study?The purpose of this expanded access program (EAP) is to provide ciltacabtagene autoleucel (cilta-cel) that does not meet the commercial release specifications of CARVYKTI and is notvailable via the local health care system in the country where the treatment is requested.THIS STUDY IS ENROLLING …
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