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Found 118 will-simon trials

A listing of will-simon medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

A Randomized Phase III Study to Evaluate Benefits of Autologous Stem Cell Transplant in Patients with Peripheral T Cell Lymphoma that Achieved a First Complete Remission (CR1) Following Induction Therapy (PTCL-STAT)

U
Utpal Dave, MD
18 years - 75 years
All genders
Phase 3
Primary: To demonstrate improvement in progression free survival (PFS) in the autologous stem cell transplant (ASCT) arm compared to the observation arm. Secondary: -To assess difference in overall survival (OS) between the observation and autologous stem cell transplant (ASCT) arm. -To evaluate the differences in study intervention benefit for PFS …
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Study on Safety and Tolerability of Investigational Medication in Advanced Solid Tumors (types of cancer that form solid masses)

N
Nabil Adra, MD
15 years - 100 years
All genders
Phase 1
This study investigates the safety and tolerability of an investigational medication in people with advanced solid tumors. Advanced solid tumors are cancers that have spread and are difficult to treat. The purpose of this study is to find out if the investigational medication is safe and to determine the best …
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Study of Investigational Combinations for Prostate Cancer

N
Nabil Adra, MD
18 years - 100 years
Male
Phase 2
This study investigates the effects of combining two investigational medications for treating prostate cancer that has spread and is resistant to standard treatments. The study focuses on adult male patients with prostate cancer that shows positive results on a specific type of scan. The purpose is to find out how …
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Study on the Use of Investigational Bone Marrow for Transplantation

J
Jodi Skiles
12 years - 80 years
All genders
This study investigates the use of investigational cryopreserved bone marrow for transplantation. The purpose is to provide a ready-to-use source of hematopoietic cell grafts for patients who do not have available living donors. Hematopoietic progenitor cells (HPCs) are special cells that can develop into different types of blood cells. This …
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Comparative Effectiveness of Interventions to Improve Screening Among Rural Women

V
Victoria Champion
50 years - 74 years
Female
The purpose of this study is to compare the effectiveness of a tailored interactive DVD (TIDVD) vs telephone patient navigation (PN) + tailored interactive DVD (TIDVD) vs Usual Care in increasing screening rates for Breast Cancer (BC), Cervical Cancer (CC), and colorectal cancer (CRC) among women 50 -74 years living …
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Study of Eye Health in Patients Using a Medication Being Studied for Cervical Cancer

S
Sharon E. Robertson
18 years - 100 years
Female
This study investigates the effects of an investigational medication on eye health in patients with recurrent or metastatic cervical cancer. Cervical cancer occurs when cells in the cervix grow uncontrollably. This study focuses on understanding any side effects related to the eyes that may arise from the treatment. A side …
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Study on Support for Cancer Patients

A
Alexia Torke
18 years - 100 years
All genders
This study investigates the impact of informational support versus spiritual care on patients with cancer. Cancer patients often face challenges in coping with their condition and making treatment decisions. Religion and spirituality can play significant roles in their experience. Therefore, this study will evaluate a spiritual care intervention delivered by …
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Study of Investigational Medication in Combination with Other Treatments for Extensive Stage Small-Cell Lung Cancer

M
Misty D. Shields, MD, PhD
18 years - 100 years
All genders
Phase 3
This study investigates the effects of an investigational medication combined with other treatments for extensive stage small-cell lung cancer (ES-SCLC). ES-SCLC is a type of lung cancer that has spread extensively within the body. The purpose is to see if the investigational medication can improve overall survival when used with …
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Investigating Fairness in Liver Transplant Referrals

L
Lauren Nephew
18 years - 75 years
All genders
This study investigates how to improve fairness in liver transplant referrals. The purpose is to develop and test a program called LT-CARE, which aims to address barriers faced by patients, healthcare providers, and the health system. The study will be conducted in five community gastroenterology practices that serve groups experiencing …
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A Non-randomized Open-label Multi-center Phase I/II Study of Phosphatidylinositol-3-kinase (PI3K) Inhibitor Copanlisib in Pediatric Patients With Relapsed/Refractory Solid Tumors or Lymphoma

J
James Croop, MD, PhD
1 years - 21 years
All genders
This study is designed to investigate whether the use of copanlisib is safe, feasible and beneficial to pediatric patients with solid solid tumors or lymphoma that are recurrent or refractory to standard therapy.
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