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Found 113 will-simon trials

A listing of will-simon medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

J
Jessica Parker Metter
18 years - 100 years
All genders
Phase 3
What is the purpose of this study?This phase III trial compares the effect of olaparib for one year versus two years, with or without bevacizumab, for the treatment of BRCA 1/2 mutated or homologous recombination deficient stage III or IV ovarian cancer. Olaparib is a polyadenosine 5'-diphosphoribose polymerase (PARP) enzyme …
A
Angela M. Richardson, MD, PhD
18 years or above
All genders
What is the purpose of this study?The purpose of this study is to look at the effect of oxygen on tumor tissue and cerebrospinal fluid(CSF). Tissue in your body is exposed to less oxygen than is in the air around you. Traditional studies use cells and tissue kept in room …
K
Kathy Miller, MD
18 years - 100 years
All genders
Phase 3
This study investigates the effects of different durations of HER2-targeted therapy in patients with early-stage HER2-positive breast cancer. HER2-positive breast cancer is a type of cancer where a protein called HER2 is found on the surface of the cancer cells. This protein can make cancer cells grow faster. The purpose …
R
Rohan Maniar
18 years - 100 years
All genders
This study investigates the use of an investigational medication in treating people with early-stage non-small cell lung cancer (NSCLC) after surgery. NSCLC is a type of lung cancer that occurs when cells in the lung grow uncontrollably. The purpose of this study is to see if the investigational medication can …
A
Anita Turk, MD
18 years - 100 years
All genders
Phase 3
This study investigates treatments for metastatic colorectal cancer, which is a type of cancer that starts in the colon or rectum and spreads to other parts of the body. The purpose of this study is to compare two treatments: one using an investigational medication with a chemotherapy regimen called mFOLFOX6, …
A
Anita Turk, MD
18 years or above
All genders
Phase 2
Interventional
This study investigates the use of an investigational medication along with a targeted therapy called olaparib for patients with metastatic pancreatic cancer. Metastatic pancreatic cancer is when the cancer has spread from the pancreas to other parts of the body. The study focuses on patients with specific genetic mutations called …
N
Naoyuki Saito, MD
18 years or above
All genders
Phase 2
Observational
What is the purpose of this study?This is a one-stage single-arm phase II clinical trial designed to prospectively test the survival prediction tool as developed by Lee et al on patients referred to radiation oncologyve treatments. Survival prediction score based on objective data includingboratory values, attendance to emergency room, and …
A
Amanda J. Saraf, DO
17 years or below
Female
What is the purpose of this study?Define and follow-up with the patients that undergo OTC for fertility preservation.Optimize techniques and quality assurance measures for freezing and thawing of ovarian tissue or gametesEstablish techniques for in vitro follicle maturation (IFM) or in vitro maturation of cumulus oocyte complexesInvestigate factors affecting successful …
R
Rita Assi
18 years - 59 years
All genders
Phase 2
What is the purpose of this study?This phase II MyeloMATCH treatment trial tests whether the standard approach of cytarabine and daunorubicin in comparison to the following experimental regimens works to shrink cancer in patients with high risk acute myeloid leukemia (AML): 1) daunorubicin and cytarabine liposome alone; 2) cytarabine and …
U
Utpal Dave, MD
18 years - 75 years
All genders
Phase 3
This study investigates the potential benefits of using high dose chemotherapy followed by a patient's own stem cells, known as an autologous stem cell transplant, in treating peripheral T-cell lymphoma. Peripheral T-cell lymphoma is a type of cancer that affects T-cells, which are part of the body's immune system. The …