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Found 122 will-simon trials

A listing of will-simon medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Study on Low-Dose Investigational Medication for Early-Stage Breast Cancer

K
Kathy Miller, MD
18 years - 100 years
All genders
Phase 3
This study investigates the use of low-dose tamoxifen compared to usual hormonal therapy in treating post-menopausal women with hormone-positive, HER2 negative early-stage breast cancer. Hormone-positive breast cancer is a type of cancer that grows in response to hormones like estrogen. HER2 negative means the cancer does not have higher levels …
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Study on Investigational Cord Blood Units

J
Jodi Skiles
100 years or below
All genders
This study investigates the safety of using investigational cord blood units (CBUs) for hematopoietic stem cell transplants in both children and adults. Hematopoietic stem cells are important for creating new blood cells. The study will carefully look at any problems that happen during or after the infusion of these CBUs.Participants …
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Translational Breast Cancer Research Consortium Biospecimen & Outcomes Repository

K
Kathy Miller, MD
18 years - 100 years
Female
The purpose of this study is to develop a repository of clinical data and outcomes, with and without corresponding specimens from individuals who have participated in TBCRC studies.
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Neoadjuvant pembrolizumab in patients with muscle-invasive bladder cancer with selective bladder sparing

J
Jennifer King
18 years or above
All genders
Phase 2
Interventional
What is the purpose of this study?Subjects with cT2-T3N0M0 urothelial cancer of the bladder will be enrolled. After completingwo cycles of pembrolizumab, subjects will undergo a restaging MRI of the abdomen and pelvis with a standard acquisition protocol (as outlined in the protocol) as well as CT chest. A CThe …
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National Liver Cancer Screening Trial (TRACER)

N
Naga Chalasani, MD
18 years - 85 years
All genders
What is this study about?The National Liver Cancer Screening Trial is an adaptive randomized phase IV Trial comparing ultrasound-based versus biomarker-based screening in 5500 patients with cirrhosis from any etiology or patients with chronic hepatitis B infection. Eligible patients will be randomized in a 1:1 fashion to Arm A using …
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Investigating the Use of an Investigational Agent for Imaging Prostate Cancer

C
Clinton Bahler, MD
18 years - 100 years
Male
Phase 2
This study investigates the use of an investigational agent for imaging prostate cancer during surgery. Prostate cancer is a disease where cells in the prostate grow in an uncontrolled way. The agent being studied is designed to target a specific protein called Prostate-Specific Membrane Antigen (PSMA), which is found in …
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A Phase II Study of Amivantamab SC (subcutaneous) in Participants with MET Amplification-Positive Stage IV or Recurrent Non-Small Cell Lung Cancer (Lung-MAP Sub-Study)

R
Rohan Maniar
18 years - 100 years
All genders
Phase 2
What is the purpose of this study?This phase II Expanded Lung-MAP treatment trial tests how well amivantamab-subcutaneous (SC) works in treating patients patients with MET amplification non-small cell lung cancer. Amivantamab-SC is a drug that reduces extra copies of the MET gene, a change present in your tumor. Giving amivantamab-SC …
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Study of Investigational Medication for Small-Cell Lung Cancer

M
Misty D. Shields, MD, PhD
18 years - 100 years
All genders
This study investigates the use of an investigational medication compared to durvalumab for people with limited-stage small-cell lung cancer (SCLC). Small-cell lung cancer is a type of cancer that starts in the lungs and is known for growing quickly. Participants in this study have already received chemotherapy and radiotherapy, which …
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Study on Monitoring and Chemotherapy for Germ Cell Tumors

S
Sandeep Batra, MD
49 years or below
All genders
Phase 3
This study investigates treatments for people with germ cell tumors, which are a type of cancer that starts in the cells that form sperm or eggs. The purpose of this study is to see how well active surveillance works for low-risk germ cell tumors and to compare two chemotherapy treatments, …
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Research Study on DNA Repair Capacity in Lung Disease

C
Catherine Sears, MD
18 years - 100 years
Accepts healthy volunteer
All genders
This study investigates the DNA repair capacity (DRC) in lung disease. DRC is a measure of how well cells can fix damage to their DNA. High DNA damage is often found in lung diseases like lung cancer and chronic obstructive lung disease (COPD), which includes emphysema and chronic bronchitis. The …
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