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Found 151 will-simon trials

A listing of will-simon medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

GRONINGEN INTERNATIONAL STUDY ON SENTINEL NODES IN VULVAR CANCER III, A PROSPECTIVE PHASE II TREATMENT TRIAL

S
Sharon E. Robertson
18 - 100
Female
Phase 2
What is the purpose of this study?The primary objective of this study is to investigate the safety of replacing inguinofemoral lymphadenectomy by chemoradiation in early stage vulvar cancer patients with a macrometastasis (>2mm) and/or extracapsular extension in the SN. The secondary objective is to evaluate the short and long-term morbidity …
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An Investigator Sponsored Study to Investigate the Safety and Efficacy of CYTALUX (PAFOLACIANINE) INJECTION for the Intraoperative Imaging of Prostate Cancer

C
Clinton Bahler, MD
18 - 100
Male
What is the purpose of this study?This is an open label trial in up to 15 subjects with biopsy confirmed prostate cancer (PCa) who have been scheduled to undergo a laparoscopic radical prostatectomy with or without robotic assistance, with pelvic lymph node dissection. This is a non-intervention trial to assess …
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Optimizing the design and functionality of the CLL Mind Map, an Innovative Digital Decision Aid with A Dynamic Graphical Interactive Interface

L
Larry Cripe, MD
18 - 100
All genders
What is the purpose of this study?Optimize the design and functionality of the CLL Mind Map based upon feedback of patients with CLL or related indolent non-Hodgkin s lymphomad their designated caregiver.THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not actively “recruited,” but …
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Randomized prospective study comparing intrathecal morphine vs intravenous methadone for postoperative analgesia following retroperitoneal lymph node dissection (RPLND)

G
Gulraj Singh Chawla
18 - 80
Male
What is the purpose of this study?At Indiana University Adult Academic Health Center (AAHC), both intrathecal morphine and intravenous methadone are the standard of care for pain management in patients undergoing retroperitoneal lymph node dissections for primary testicular cancer, and both have had great success.  In this study, we propose …
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Pilot Study to Determine Pro-Inflammatory Cytokine Kinetics During Immune Checkpoint Inhibitor Therapy

T
Tyler Shugg
18 or above
All genders
Observational
What is the purpose of this study?This research aims to identify clinical strategies to manage adverse events during immune checkpoint inhibitor therapy by (1) determining the impact of checkpoint inhibitors on metabolism through major CYP enzymes and (2) identifying associations between pro-inflammatory cytokine concentrations and negative clinical outcomes during checkpoint …
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Evaluation of the Concordance Between Transbronchial Needle Aspiration and Bronchoscopic Core Needle Biopsy for PD-L1 Scoring and Histology in NSCLC

C
Christopher Kniese
18 - 100
All genders
What is the purpose of this study?Investigate PD-L1 protein expression from samples of lung masses or lymph nodes obtained by transbronchial needle aspiration (TBNA) versus core biopsy  done through a specific bronchoscope that uses endobronchial ultrasound (EBUS) for localizing these targets. Currently, EBUS with TBNA is standard of care for …
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Examining Genetic Ancestry, Allostatic Load and Treatment Completion among Patients with Breast Cancer

T
Tarah Ballinger, MD
18 - 100
Female
What is the purpose of this study?The main purpose of this study is to learn more about how genetic ancestry affects treatment completion for patients who are diagnosed with breast cancer. THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not actively “recruited,” but …
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Using a Novel Lay Patient Navigation Model to Improve Cascade Testing Rates for Hereditary Cancer Syndromes in Black Patients and Their Family Members

N
Nawal Kassem
18 - 100
All genders
What is the purpose of this study?The purpose of this study is to improve genetic testing rates in families of Black patients who are found to have a hereditary cancer syndrome.THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not actively “recruited,” but are …
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Evaluating Disparities in Precision Oncology: An Observational Trial in the context of a Real-World Academic Practice Model (EDPO)

B
Bryan Schneider, MD
18 or above
All genders
Observational
What is the purpose of this study?This is a non-randomized observational trial designed to collect detailed clinical, social determinant, and genomic data from patients enrolled in molecular oncology tumor boards across four comprehensive cancer centers.THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not …
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A Pilot Study of a Triadic Communication Intervention to Improve Supportive Oncology Care Delivery Among Patients and Caregivers Facing Advanced Cancer

K
Kristin Levoy
18 - 100
Female
What is the purpose of this study?The purpose of this study is to help test an idea designed to foster more supportive talk between doctors or nurse practitioners, patients, and caregivers during an outpatient oncology appointment. A caregiver is the person the patient identifies as primarily involved in their healthcare. …
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