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Found 113 will-simon trials
A listing of will-simon medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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Misty D. Shields, MD, PhD
This study investigates the use of an investigational medication compared to durvalumab for people with limited-stage small-cell lung cancer (SCLC). Small-cell lung cancer is a type of cancer that starts in the lungs and is known for growing quickly. Participants in this study have already received chemotherapy and radiotherapy, which …
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Sandeep Batra, MD
This study investigates treatments for people with germ cell tumors, which are a type of cancer that starts in the cells that form sperm or eggs. The purpose of this study is to see how well active surveillance works for low-risk germ cell tumors and to compare two chemotherapy treatments, …
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Catherine Sears, MD
This study investigates the DNA repair capacity (DRC) in lung disease. DRC is a measure of how well cells can fix damage to their DNA. High DNA damage is often found in lung diseases like lung cancer and chronic obstructive lung disease (COPD), which includes emphysema and chronic bronchitis. The …
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Nabil Adra, MD
This study investigates maintenance treatment with oral etoposide or observation in patients with relapsed germ cell tumors (GCT) who have received high-dose chemotherapy and peripheral blood stem cell transplant. Germ cell tumors are a type of cancer that begins in the cells that give rise to sperm or eggs. This …
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Jodi Skiles
The primary purpose of the Research Sample Repository is to make blood samples available forh studies related to histocompatibility and hematopoietic cell transplantation (HCT)her cellular therapy. Representatives of participating centers and investigators or research groups may requesth samples contained in the Research Sample Repository for the purpose ofducting research including: …
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Lisa Landrum, MD, PhD, MS
This phase III trial compares the effect of sentinel lymph node mapping to standard lymph node dissection in reducing the risk of swelling in the legs (lymphedema) in patients undergoing a hysterectomy for stage I endometrial cancer. Standard lymph node dissection removes lymph nodes around the uterus during a hysterectomy …
Development of a Genetic Algorithm to Predict Anthracycline-Induced Cardiomyopathy in Adult Patients
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Todd Skaar
What is the purpose of this study?The purpose of this prospective study is to assess the accuracy of four previously-studied genetic variations to predict the development of cardiomyopathy (i.e., a disease of the heart muscle that reduces the ability of your heart to pump blood to your body) in adult …
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Shadia Jalal, MD
The purpose of this study is to investigate a rapid autopsy program for patients with Small Cell Lung Cancer (SCLC) at the Indiana University Simon Comprehensive Cancer Center. Small Cell Lung Cancer is a type of lung cancer characterized by fast-growing tumors. This study will involve collecting tumor tissue from …
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Greg Durm, MD
This study investigates the effectiveness and safety of an investigational medication compared to the investigator's choice of monotherapy treatment in patients with head and neck squamous cell carcinoma (HNSCC) that is incurable, metastatic, or recurrent. HNSCC is a type of cancer that occurs in the squamous cells lining the head …
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Michael W. Sim, MD
This study investigates a new approach for treating HPV-positive oropharyngeal squamous cell carcinoma (OPSCC). The purpose of this study is to see if reducing the intensity of treatment, based on levels of ctHPVDNA (pieces of cancer DNA in blood samples), can be as effective as the standard treatment. OPSCC is …
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