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Found 116 will-simon trials

A listing of will-simon medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

A Phase 3, Randomized, Open-Label Study to Compare the Efficacy and Safety of Anitocabtagene Autoleucel Versus Standard of Care Therapy in Participants With Relapsed/Refractory Multiple Myeloma

R
Rafat Abonour, MD
18 years - 100 years
All genders
Phase 3
What is the purpose of this study?The goal of this study (iMMagine-3) is to compare the study drug, anitocabtagene autoleucel to standard of care therapy (SOCT) in participants with relapsed/refractory multiple myeloma who have received 1 to 3 prior lines of therapy, including an anti-CD38 monoclonal antibody and an immunomodulatory …
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Study of Investigational Medication vs Standard Treatments in Cancer That Has Spread

N
Nabil Adra, MD
18 years - 100 years
Male
Phase 3
This study investigates the treatment of metastatic castration-resistant prostate cancer (mCRPC), which is a type of cancer that continues to grow even when the amount of testosterone in the body is reduced to very low levels. The purpose of this study is to compare overall survival between participants receiving an …
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Routine Carbohydrate Loading in Patients Undergoing Complex Hepatobiliary Surgery

T
Tom Korte Maatman
18 years - 100 years
All genders
What is the purpose of this study?Test the effect of preoperative carbohydrate loading on hospital LOS after complex hepatopancreaticobiliary surgeries.Test the effect of preoperative carbohydrate loading on other post-operative complications including surgical site infections (SSI), readmissions, delayed gastric emptying (DGE), insulin resistance and deathTHIS STUDY IS ENROLLING BY INVITATION ONLY …
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Detecting Prostate Cancer Return with Imaging

C
Clinton Bahler, MD
18 years - 100 years
Male
Phase 3
This study investigates how well a special scan can find prostate cancer that has come back after treatment. Prostate cancer is a disease where cells in the prostate grow out of control. The study uses a technique called PET/CT, which stands for Positron Emission Tomography and Computed Tomography. This scan …
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Study of Investigational Medication for Older Adults with Specific Type of Blood Cancer

R
Rita Assi
18 years - 100 years
All genders
Phase 2
This study investigates treatments for older adults with a type of blood cancer called acute myeloid leukemia (AML) that has a specific mutation known as FLT3. The purpose is to compare different treatments to see which is more effective. AML is a cancer of the blood and bone marrow, where …
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Investigating Imaging Techniques for Detecting Metastatic Disease in Pancreatic Cancer

C
Cindy Yuan
18 years or above
All genders
This study investigates the use of a special imaging test called [¹⁸F]FAPI-74 PET/CT to find cancer that has spread in people with a type of pancreatic cancer known as pancreatic ductal adenocarcinoma. Pancreatic ductal adenocarcinoma is a disease where cancer cells form in the tissues of the pancreas. The purpose …
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Expanding Lung Cancer Screening to Persons who do not Meet the 2021 USPSTF Guidelines Criteria: A Study from End Lung Cancer Now

J
Julian Marin Acevedo
18 years - 100 years
All genders
What is the purpose of this study?The primary objective of this study is to estimate the proportion of individuals with lung cancer seen at Indiana University and Eskenazi Health Centers who do not meet the 2021 USPSTF criteria for lung cancer screening. THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent …
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Research Study for Muscle-Invasive Bladder Cancer

T
Tareq Salous
18 years - 100 years
All genders
Phase 2
This study investigates muscle-invasive bladder cancer, a type of cancer that grows into the muscle layer of the bladder. The purpose is to see how well an investigational medication combined with another treatment works for this type of cancer. The study involves patients with muscle-invasive bladder cancer receiving treatment and …
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Study on Treatment for High-risk Renal Cell Carcinoma

J
Jennifer King
18 years - 100 years
All genders
This study investigates the effects of adding an investigational medication to a standard treatment for patients with high-risk renal cell carcinoma (RCC). RCC is a type of kidney cancer. The purpose of this study is to see if the investigational medication, when combined with the standard treatment, works better than …
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Study on Safety and Tolerability of Investigational Medication in Advanced Solid Tumors (types of cancer that form solid masses)

N
Nabil Adra, MD
15 years - 100 years
All genders
Phase 1
This study investigates the safety and tolerability of an investigational medication in people with advanced solid tumors. Advanced solid tumors are cancers that have spread and are difficult to treat. The purpose of this study is to find out if the investigational medication is safe and to determine the best …
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