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Found 111 will-simon trials
A listing of will-simon medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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Rohan Maniar
This study investigates the effects of adding an investigational medication, cemiplimab, to the usual treatment of docetaxel and ramucirumab for patients with stage IV or recurrent non-small cell lung cancer. This type of lung cancer is advanced and may have returned after previous treatment. Cemiplimab is a monoclonal antibody that …
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Tarah Ballinger, MD
This study investigates whether adding chemotherapy to ovarian function suppression and hormone therapy improves breast cancer-free survival in premenopausal women. The focus is on those with early-stage breast cancer that is estrogen receptor-positive and HER2-negative. The study will compare outcomes between those receiving chemotherapy in addition to hormone treatments and …
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Nabil Adra, MD
The purpose of this study is to investigate the long-term effects of chemotherapy and bone marrow transplant on the heart health of testicular cancer survivors. Testicular cancer often affects young adult males, and the treatment can include chemotherapy with platinum-based drugs. This study looks at changes in cholesterol, hormones, and …
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Samantha Armstrong
What is the purpose of this study?This phase II trial compares the effect of immunotherapy (pembrolizumab) plus chemotherapy (doxorubicin) to chemotherapy (doxorubicin) alone in treating patients with undifferentiated pleomorphic sarcoma (UPS) or a related poorly differentiated sarcoma that has spread from where it first started to other places in the …
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Lisa Landrum, MD, PhD, MS
This study investigates treatments for women with platinum-resistant epithelial ovarian cancer, which is a type of cancer that does not respond to platinum-based chemotherapy. The purpose is to compare the effects of different treatments, including an investigational medication called nemvaleukin, either alone or in combination with another treatment, pembrolizumab, against …
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Naoyuki Saito, MD
This study investigates the treatment of breast cancer in patients who have hormone-sensitive, HER-2 negative tumors with a low recurrence score. The purpose is to understand if breast conservation surgery with only endocrine therapy is as effective as combining it with radiation therapy in preventing the return of cancer in …
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Kevin Shiue
What is the purpose of this study?This phase III trial compares the effect of stereotactic radiosurgery to standard of care memantine and whole brain radiation therapy that avoids the hippocampus (the memory zone of the brain) for the treatment of small cell lung cancer that has spread to the brain. …
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Tarah Ballinger, MD
This study investigates treatments for people with HER2-positive breast cancer. HER2-positive means that the cancer cells have more HER2 protein than normal, which can cause cancer cells to grow. The study looks at using a combination of investigational medication injections and hormone therapy after surgery. The investigational medications are trastuzumab …
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Sherif Farag, MD
This study is an access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs) in pediatric and adult patients with hematologic malignancies and otherdications.
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Jessica Parker Metter
What is the purpose of this study?The OnPrime study is a multi-center, randomized open-label phase 3 study evaluating the safety and efficacy of Olvi-Vec followed by platinum-doublet chemotherapy and bevacizumab compared to the Active Comparator Arm with Physician's Choice of chemotherapy and bevacizumab in women diagnosed with platinum-resistant/refractory ovarian cancer …
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