A listing of will-simon medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This study investigates the effects of adding an investigational medication, cemiplimab, to the usual treatment of docetaxel and ramucirumab for patients with stage IV or recurrent non-small cell lung cancer. This type of lung cancer is advanced and may have returned after previous treatment. Cemiplimab is a monoclonal antibody that …
What is the purpose of this study?To compare cardiovascular health literacy, cardiovascular risk, and cardiovascular disease between African American and White men who are receiving or completed androgen deprivation for treatment of prostate cancer. To explore clinical, socioeconomic, and demographic predictors of CVD health literacy. THIS STUDY IS ENROLLING BY INVITATION …
What is the purpose of this study?This phase II trial compares the effect of immunotherapy (pembrolizumab) plus chemotherapy (doxorubicin) to chemotherapy (doxorubicin) alone in treating patients with undifferentiated pleomorphic sarcoma (UPS) or a related poorly differentiated sarcoma that has spread from where it first started to other places in the …
What is the purpose of this study?This phase III trial studies magnetic resonance imaging (MRI) surveillance and prophylactic cranial irradiation (PCI) to see how well they work compared to MRI surveillance alone in treating patients with small cell lung cancer. MRI scans are used to monitor the possible spread of …
This phase I/II trial studies the side effects and best dose of WEE1 inhibitor MK-1775 and irinotecan hydrochloride in treating younger patients with solid tumors that have come back or that have not responded to standard therapy. WEE1 inhibitor MK-1775 and irinotecan hydrochloride may stop the growth of tumor cells …
The investigators propose to conduct a dose-escalation trial of an FDA-approved antiepileptic drug, lacosamide, added to opioid therapy in patients with chronic abdominal pain fromhronic pancreatitis (CP). This pilot trial will test the feasibility of the study design andvide reassurance regarding the tolerability and safety of lacosamide used concomitantly with …
What is the purpose of this study?This phase III trial compares the effect of stereotactic radiosurgery to standard of care memantine and whole brain radiation therapy that avoids the hippocampus (the memory zone of the brain) for the treatment of small cell lung cancer that has spread to the brain. …
This study is an access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs) in pediatric and adult patients with hematologic malignancies and otherdications.
This study investigates the effects of receiving regional radiotherapy compared to no regional radiotherapy in patients with low risk node positive breast cancer. Breast cancer is a disease where cells in the breast grow uncontrollably. This study includes two study arms. In one arm, participants who had breast conserving surgery …
