This study aims to help patients at a free eye clinic better understand and manage dry eye symptoms. We will provide education, artificial tears, and washcloths for warm compress, then follow up to see if their symptoms improve. Our goal is to make dry eye screening, education, and treatment care more accessible and effective for people in underserved communities.THIS STUDY IS ENROLLING BY INVITATION ONLY - Patients attending the IUSOC Eye Clinic will be screened for dry eye symptoms during their routine visit using the OSDI questionnaire. Those who screen positive and meet eligibility criteria will be informed about the study by trained medical student volunteers. Interested patients will be asked for verbal consent to participate and to provide contact information and to return to clinic for follow-up approximately four weeks later. Patients will be recruited in person during their scheduled clinic visit after completing intake. Initial study awareness may be introduced in the clinic’s waiting area in a general, non-specific way. Patients who express interest will be approached individually in a semi-private space to discuss study details and provide consent. 

Researchers are looking for a better way to treat children who have heart failure with left ventricular systolic dysfunction (LVSD). Heart failure is a serious condition where the heart is unable to pump enough blood to meet the body's needs. This can lead to symptoms like shortness of breath, fatigue, and poor growth in children.The study treatment, finerenone (also called BAY94-8862), works by blocking a protein involved in inflammation, scarring, and thickening of the heart and blood vessels. This may help the heart to pump blood more effectively. This is the first study to explore its use specifically for children with heart failure and LVSD.The main purpose of this study is to learn if finerenone works to help the heart compared to placebo in children with heart failure and LVSD. For this, the researchers will collect and analyze data on the levels of a protein called NT-proBNP in the blood, which indicates heart stress, and monitor the safety of the treatment.THIS STUDY IS ENROLLING BY INVITATION ONLY 

This is a non-interventional method comparison study using prospectively collected nasal swab specimens collected from subjects via the informed consent process. The study is designed to assist MBI in determining the reference method to be used in Meridian M10 MRSA/SA assay clinical study.  The objective of this Beta Testing Protocol is to aid Meridian Bioscience Inc. (MBI) in determining the reference method to be used in the Meridian M10 MRSA/SA assay clinical study.THIS STUDY IS ENROLLING BY INVITATION ONLY 

The purpose of the study is to learn more about children’s mental health. We are hoping to better understand how to predict and diagnose common mental health diagnoses in children.THIS STUDY IS ENROLLING BY INVITATION ONLY - A two-step process will be used to identify and screen potential participants. In step 1, potentially eligible patients are identified either: (a) by research staff present in the outpatient clinics (OHSU, Seattle Children’s, MGH, and Indiana University) identifying the patient at the time of visit, or (b) using a “Best Practice Alert” in the Epic® electronic health record, which scans patient medical records in real time and notifies research staff when a patient meets initial eligibility based on visit presenting problem and diagnosis. In step 2, research staff will inform families about the study (either in person or via phone/email), screen for all inclusionary and exclusionary criteria and if eligible, conduct assent/consent and enrollment procedures via electronic signature.

The purpose of this study is to offer women with a history of gestational diabetes access to diabetes prevention programming; their children 10 and older can participate.THIS STUDY IS ENROLLING BY INVITATION ONLY - Women will be recruited for this study in a variety of ways, including women participants in two existing IU research studies (1808964513 & 1011003392) will be recruited if they indicate it is ok to be contacted. We will recruit women who consented to be contacted for future research while participants in the prior studies. We will recruit women via telephone calls and recruitment letters in the mail.

Study LX2006-02 is a prospective, longitudinal, low-intervention, multicenter, global study aimed at characterizing the nature and rate of cardiac disease progression in participants with genetically confirmed FA-CM.THIS STUDY IS ENROLLING BY INVITATION ONLY -  Participants with a confirmed diagnosis of FA-CM, specifically identified by LVH by cMRI), will be contacted by the research team about study participation.  By including both adult and pediatric populations, the study aims to capture a range of disease progression across different age groups. Excluding individuals with confounding cardiovascular (CV) conditions enhances the focus on the specific impacts of FA. Overall, these criteria are intended to create a relevant study population to better understand the natural progression of the cardiac aspects of this condition.

The purpose of this research is to evaluate the overall use of the WounDx medical device in a clinical setting, such as a hospital. The WounDx device is experimental and not yet approved by the United States Food and Drug Administration (FDA). WounDx uses information about a patient's wound to generate a report that a surgeon may use to help determine when to close or not close the wound. The final decision to close the wound remains with the surgeon. The results from this pilot trial will inform a larger pivotal trial.THIS STUDY IS ENROLLING BY INVITATION ONLY