Health Research
and Clinical Studies

All IN for Health provides a list of hundreds of active health studies happening right here in Indiana. These health studies are conducted by faculty at Indiana University, Purdue University, and the University of Notre Dame.

All IN for Health provides a list of hundreds of active health studies happening right here in Indiana. These health studies are conducted by faculty at Indiana University, Purdue University, and the University of Notre Dame.

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Aging
Children, Families & Pregnancy
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Asthma,Lungs & Allergies
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Brain, Spine & Nervous System
Covid-19 & Infectious Disease
Diabetes, Heart and Blood Vessels
Digestive System (GI), Bowel & Liver
Health Mental, Behavioral Health & Developmental Conditions
Healthy Volunteer
Cancer
Diet, Nutrition, Exercise, & Sleep

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Aging
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By donating a small blood sample, you can help researchers discover better treatments and improve health across Indiana.

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All IU Health Patients of Any Age

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Browse studies by

Recently added/updated trials

An Observational Study of Lung Screening in Individuals at High Risk for Lung Cancer Who Do Not Meet the Uspstf Criteria

J
Julian Marin Acevedo
50 years - 80 years
All genders
Study purposse:  Describe the demographics, risk factors for lung cancer, and baseline Lung Rads score of individuals enrolled in this observational study. Using descriptive statistics, compare the demographics and Lung Rads score of the participants enrolled in this study with those participating in the NLST and NELSON studies. Using descriptive statistics, compare the demographics and Lung Rads score of the participants enrolled in this study with a cohort of participants in the lung screening program at IU HealthParticipants will be recruited by advertisements and at community events. Participants will undergo their lung screening at IU Health fixed lung screening sites or through the IU Health mobile lung screening program.THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not actively “recruited,” but are screened by their physician for appropriate clinical trial(s) at the time of their routine clinic visit. Occasionally, a patient may be a self-referral or physician referral, but are still screened for appropriate clinical trials at the time of their routine clinic visit. PI and staff may send copies of relevant consent forms to these patients to look over prior to actually consenting or enrolling them. This may take place at the patient's visit at which the consent is presented or the patient's next visit to the outpatient hematology/oncology clinic.  Interested in participating? For more information about this research study or other cancer-related clinical trials at IU Simon Comprehensive Cancer Center, please contact:IU Clinical Trials Office Email: iutrials@iu.edu Phone: (317) 278-5632
 Are You Caring For A Loved One With Cancer? We’d Love To Hear From You

Are You Caring For A Loved One With Cancer? We’d Love To Hear From You

V
Victoria Champion
18 years or above
Accepts healthy volunteer
All genders
Help us learn how to better support rural families facing cancer.  Take part in this study and help improve care for caregivers like you.  Caregivers play a vital role in helping cancer patients get the best possible care. But caregiving—especially in rural communities—can be demanding and emotionally overwhelming. Many caregivers face challenges related to stress, mental health, and balancing complex at‑home treatment responsibilities. Rural caregivers often face additional barriers such as fewer local resources and longer travel distances for care.That is why researchers at Indiana University are looking to speak with caregivers of people with solid tumor cancers who live in rural areas of Indiana.Your experiences matter.  By sharing your story, you can help shape better care for other caregivers and the people they love.
Check Eligibility
Online study
 Adolescents Needed for Sweetened Beverages Study

Adolescents Needed for Sweetened Beverages Study

N
Nana Gletsu Miller
12 years - 18 years
Accepts healthy volunteer
All genders
Why is this study being done?The goal of this study is to better understand how preferences for sweet flavors affect dietary habits, heart and metabolic health. Who can take part?We are looking for  adolescents (ages 12-18) who consume sugary sodas and their families (only one parent/guardian can participate). Participants must also be able to attend study visits at the Nutrition Research Center on either IU Indianapolis or IU Bloomington campus or Purdue University (West Lafayette).

Flavor-Masked Foods: Making Nutritious Eating Fun for Kids with Autism

Anita Panjwani
3 years - 12 years
All genders
This study is looking at how flavor-masked foods might be more acceptable to children with autism. Autism spectrum disorder (ASD) is a condition that affects how a person thinks, learns, and experiences their surroundings. The purpose of this study is to see if masking strong tastes and smells of certain nutritious foods, like broccoli sprouts and moringa, can encourage children with autism to try them.All study activities can be completed online at home - no in-person visits or travel is required.We are inviting parents/caregivers of a child aged 3-12 years who is diagnosed with Autism spectrum disorder (ASD) to participate.
Learn More
Online study
 Rural Indiana Residents Needed for Gut Health Study

Rural Indiana Residents Needed for Gut Health Study

P
Patricia Wolf
18 years - 80 years
Accepts healthy volunteer
All genders
Have you ever wondered how things you eat or drink affect the bacteria in your gut?   Do you live in a rural Indiana area? Researchers from the Department of Nutrition Science at Purdue University are looking at a how nutrient called cysteine [pronounced SIS-tee-een] is related to bacteria in our gut and early-onset colorectal cancer risk (EOCRC). In rural areas, it can be hard to find healthy foods. This study also wants to find out if these challenges lead people to eat more foods that contain high amounts of cysteine, and how this might affect the bacteria in their gut and their health.This study can be completed entirely from your own home - NO in-person visits are required.Who can take part?Individuals, ages 18-80, who are generally healthy (have no abnormal GI issues) and live in a county with less than 50,000 residents or live over 10 miles from their nearest grocery store.
Check Eligibility
Online study

Pilot trial to determine Relationship between Troponin Kinetics and Hemorrhagic MI

R
Rohan Dharmakumar
100 years or below
All genders
This study is a prospective, cohort study to determine the quantitative threshold differences in troponin-I level between hemorrhagic and non-hemorrhagic myocardial infarction (MI).

Forager-2: A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Efficacy and Safety of Vepugratinib Combined with Enfortumab Vedotin and Pembrolizumab in Adults with Untreated Locally Advanced or Metastatic Urothelial Carcinoma with an Fgfr3 Genetic Alteration.

T
Tareq Salous
18 years - 100 years
All genders
Phase 3
This phase II clinical trial tests how well pembrolizumab plus enfortumab vedotin prior to and after radical nephroureterectomy works in treating patients with high-risk upper tract urothelial cancer. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Enfortumab vedotin (EV) is a monoclonal antibody, enfortumab, linked to an anticancer drug called vedotin. It works by helping the immune system to slow or stop the growth of cancer cells. Enfortumab attaches to a protein called nectin-4 on cancer cells in a targeted way and delivers vedotin to kill them. It is a type of antibody-drug conjugate. Radical nephroureterectomy (RNU) is the surgical removal of a kidney and its ureter. Giving pembrolizumab plus enfortumab vedotin before surgery may make the tumor smaller and may reduce the amount of normal tissue that needs to be removed and giving pembrolizumab after surgery may kill any remaining cancer cells. Interested in participating? For more information about this research study or other cancer-related clinical trials at IU Simon Comprehensive Cancer Center, please contact:IU Clinical Trials Office Email: iutrials@iu.edu Phone: (317) 278-5632