Health Research
and Clinical Studies

All IN for Health provides a list of hundreds of active health studies happening right here in Indiana. These health studies are conducted by faculty at Indiana University, Purdue University, and the University of Notre Dame.

All IN for Health provides a list of hundreds of active health studies happening right here in Indiana. These health studies are conducted by faculty at Indiana University, Purdue University, and the University of Notre Dame.

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Aging
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Covid-19 & Infectious Disease
Diabetes, Heart and Blood Vessels
Digestive System (GI), Bowel & Liver
Health Mental, Behavioral Health & Developmental Conditions
Healthy Volunteer
Cancer
Diet, Nutrition, Exercise, & Sleep

Browse by Featured categories

Aging
Children, Families & Pregnancy
Dental
Online
Alcohol, Tobacco, or Other Substance Use
Alzheimer’s Disease & Dementia
Asthma,Lungs & Allergies
Bones, Muscles and Joints
Brain, Spine & Nervous System
Covid-19 & Infectious Disease
Diabetes, Heart and Blood Vessels
Digestive System (GI), Bowel & Liver
Health Mental, Behavioral Health & Developmental Conditions
Healthy Volunteer
Cancer
Diet, Nutrition, Exercise, & Sleep

Browse by Featured categories

Aging
Alcohol, Tobacco and Substance Use
Brain, Spine and Nerves
Cancer
Diabetes
Diet, Exercise and Nutrition
Healthy Volunteers
Mental and Behavioral Health
Alzheimer’s Disease and Dementia
Autoimmune Disease
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Bones, Muscles and Joints
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Online Studies
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Help Shape the Future of Health
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By donating a small blood sample, you can help researchers discover better treatments and improve health across Indiana.

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All IU Health Patients of Any Age

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What Is Involved?

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Why does it Matter?

By taking part, you're helping improve care for you, your loved ones, and people across Indiana.

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Browse studies by

Recently added/updated trials

 ARE YOU PREGNANT OR A NEWLY EXPECTING MOM?  JOIN THE HEARTLAND STUDY!

ARE YOU PREGNANT OR A NEWLY EXPECTING MOM? JOIN THE HEARTLAND STUDY!

D
David Haas, MD
18 years - 40 years
Accepts healthy volunteer
Female
DID YOU KNOW?  Herbicides are widely used in the Heartland, and farmers are using these chemicals more than ever before. Several studies have raised concern that some of the herbicides  may be associated with reproductive disorders, certain birth defects, and developmental disorders. What are herbicides? Herbicides are a type of pesticide that are used to protect our food crops, trees, vines, and pastures from harmful weeds. Some herbicides are also used in and around our homes, parks, sports fields, and golf courses. Herbicide use has increased significantly since the 1990s and is projected to rise rapidly on corn and soybean farms in the Midwest for the next 5-10 years.  As more pounds are applied, higher levels of human exposure are expected.    What Is the Heartland Study?Mother-infant pairs living in the Midwest will be followed throughout pregnancy, infancy and early childhood to observe health and development in order to better understand the effects of prenatal herbicide exposures. Your participation will help researchers to increase their knowledge about how herbicide exposure might affect pregnancy, newborn health, child childhood development, and future generations.

A Phase 3B/4, Multicenter, Parallel-Group, Double-Blind, Placebo Controlled, Two-Arm, Long-Term Study to Evaluate the Safety and Efficacy of Saroglitazar Magnesium on Clinical Outcomes in Participants With Primary Biliary Cholangitis (Pbc)

R
Raj Vuppalanchi, MD
18 years - 100 years
All genders
Phase 3
Interventional
The purpose of this study is to evaluate the effect of saroglitazar magnesium compared to placebo, based on time to the first occurrence of the defined clinical outcome events in participants with PBC.THIS STUDY IS ENROLLING BY INVITATION ONLY 
 GLP-1 Medications and Food Experiences Study

GLP-1 Medications and Food Experiences Study

R
Richard Mattes
18 years - 65 years
All genders
Have you recently started a GLP-1?  You may qualify for a paid research study to help us learn how weight loss medications affect taste, appetite, and food choices.Our study is exploring how certain weight-loss medications may affect how adults with obesity experience food. These medications, known as GLP-1 receptor agonists, are often used to support weight loss.Study participation includes two in-person visits at Purdue University (West Lafayette, IN) and several short online activities over about two weeks.
 We Want to Hear From Adults Ages 60 and Older—Share Your Experience Living in the Indianapolis Community

We Want to Hear From Adults Ages 60 and Older—Share Your Experience Living in the Indianapolis Community

A
Aqueasha Martin-Hammond
60 years or above
Accepts healthy volunteer
All genders
Are you 60 years or older and living in or near Indianapolis, IN?  We would LOVE to hear about your experiences living in your community. This study is about how older adults find and use local services and support that help them live independently. These may include things like transportation, health services, community activities, and ways to get information.We also want to learn about your hopes for the future and what you think about new technology, like artificial intelligence (AI), and how it might help people find community resources in the future.Help us learn more about how how Indianapolis supports older adults. Your voice can help us better understand what older adults need to live well in their communities.
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Online study

Preember: A Phase 2, Open-Label Study Evaluating Imlunestrant in Premenopausal Women with Estrogen Receptor-Positive, Her2-Negative Breast Cancer

R
Rina Yadav
18 years or above
Female
Phase 2
Cohort 1: - Assess the effect of imlunestrant versus tamoxifen on tumor cell proliferation (Ki-67). - Assess the effect of imlunestrant versus imlunestrant + goserelin on tumor cell proliferation (Ki-67).Cohort 2: - Assess the rate of symptomatic or complex ovarian cysts with imlunestrant treatment without OFS.Interested in participating? For more information about this research study or other cancer-related clinical trials at IU Simon Comprehensive Cancer Center, please contact the IU Clinical Trials Office at:Email: iutrials@iu.edu Phone: (317) 278-5632

A Single Arm, Multicenter, Prospective, Open Label, Longitudinal Phase 3 Study of Prostate Specific Membrane Antigen (Psma) Positron Emission Tomography (Pet) Combined With Magnetic Resonance Imaging (Mri) Compared to Standard of Care (Soc) for the Detection of Prostate Cancer (Pca).

C
Clinton Bahler, MD
18 years - 100 years
Male
This is an open label, longitudinal Phase 3 study of prostate specific membrane antigen (PSMA) positron emission tomography (PET) combined with magnetic resonance imaging (MRI) compared to standard of care (SOC) for the detection of prostate cancer (PCa).THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not actively “recruited,” but are screened by their physician for appropriate clinical trial(s) at the time of their routine clinic visit. Occasionally, a patient may be a self-referral or physician referral, but are still screened for appropriate clinical trials at the time of their routine clinic visit. PI and staff may send copies of relevant consent forms to these patients to look over prior to actually consenting or enrolling them. This may take place at the patient's visit at which the consent is presented or the patient's next visit to the outpatient hematology/oncology clinic.  Interested in participating? For more information about this research study or other cancer-related clinical trials at IU Simon Comprehensive Cancer Center, please contact:IU Clinical Trials Office:Email: iutrials@iu.edu Phone: (317) 278-5632

A Randomized, Double-Blind, Active-Control, Multicenter Phase 3 Trial of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Renal Cell Carcinoma

J
Jennifer King
18 years - 100 years
All genders
Phase 3
The purpose of the study is to evaluate the progression-free survival (PFS) of casdatifan versus placebo when each is given in combination with cabozantinib in adult patients with confirmed advanced or metastatic clear cell Renal Cell Carcinoma who have experienced progression on or after prior anti-PD-1 or anti-PD-L1 immunotherapy.Interested in participating? For more information about this research study or other cancer-related clinical trials at IU Simon Comprehensive Cancer Center, please contact:IU Clinical Trials Office Email: iutrials@iu.edu Phone: (317) 278-5632