In this study, we want to learn how people who have had genomic testing understand and use their results. Genomic testing looks at your DNA to check for genetic changes that may affect your health or risk for certain conditions. We want to hear how this information shapes the choices you make and who you decide to share it with, like your doctor or family. Our research team is looking for people who are 18+, live in the US, and have previously used genomic testing services (e.g., 23andMe, Ancestry.com, medical system genetic testing). Participants will engage in a 1 hour focus group session either online or in-person and receive a $20 Amazon gift card as compensation. Location: In-person at Monroe County Library - Downtown Location or IU Bloomington campus, or online on Zoom.

Why is this study being done?Cardiokidney Metabolic Syndrome or CKM is a new syndrome recognized by the American Heart Association and occurs when an individual has a combination of conditions which includes being overweight, in addition to having metabolic risk factors (hypertriglyceridemia [≥135 mg/dL], hypertension, metabolic syndrome, diabetes), or chronic kidney disease.  Researchers at Indiana University are conducting a study to learn more about how to promote exercise among individuals with CKM. CKM may have the potential to be reversed by participating in regular exercise. Findings from this study will help us understand physical activity levels among individuals with CKM, with the goal of designing an effective exercise program for those individuals. Who can take part?Adults (ages 18 and older) who are at risk of developing Cardiokidney Metabolic Syndrome (CKM).

Take the First Step Toward Feeling Better—Join Our Depression Study Today!Living with depression can feel heavy, even on your best days.  If you’re looking for new options—or simply wondering what else might help—you’re not alone. This research study is exploring a possible new treatment for major depression, and you may be able to take part. Your experience could help bring new hope to you and others who face depression every day.We’re looking for people like you to help us learn about brenipatide, a new medicine that might help with major depressive disorder (MDD).  In this study, we want to learn more about the safety and effectiveness of brenipatide and if it can help lower your depression symptoms and keep them from coming back.This study may be a good fit for you if:You have been diagnosed with major depressive disorder (MDD).You are taking a stable depression medicine.You do not have type 1 diabetes, recent substance use problems, or certain other mental health conditions.You can attend study visits at the IU Health Neuroscience Center in Indianapolis, IN and follow simple study steps, like giving yourself injections and filling out short logs or questionnaires.

We are looking for people of all ages, regardless of health condition, to take part in a study that is looking for new treatments for bone and muscle disorders.Bone and muscle disorders are the leading cause of disabilty in the United States. Researchers want to find out more about how people are affected by aging, injury, disease and illness. Your participation will help advance the diagnosis and treatment of bone and muscle disorders.

Researchers at Purdue University are studying why some people with chronic kidney disease (CKD) may be more likely to lose their balance or fall.People with CKD can sometimes have changes in their bones, blood vessels, or brain that may affect strength, balance, or walking. We want to learn more about what causes these changes and how to reduce the risk of falling.By joining this study, you can help us learn what affects balance and strength in people with CKD and how to lower the risk of falling.

Have you recently started a GLP-1?  You may qualify for a paid research study to help us learn how weight loss medications affect taste, appetite, and food choices.Our study is exploring how certain weight-loss medications may affect how adults with obesity experience food. These medications, known as GLP-1 receptor agonists, are often used to support weight loss.Study participation includes two in-person visits at Purdue University (West Lafayette, IN) and several short online activities over about two weeks.

Still searching for relief from depression?  Have you tried multiple treatments for depression without success? You may have another option. When treatments haven’t worked, research may offer a new path. The Abbott TRANSCEND study is a research study for adults with depression who have not felt better after trying at least four different antidepressant medications. The purpose of the study is to learn how safe and effective a treatment called deep brain stimulation (DBS) may be for people with treatment-resistant depression. DBS uses a medical device made by Abbott to deliver gentle electrical signals to specific areas of the brain. This treatment is still being studied and is not yet approved for this use.You may qualify to join this study if you:Are between the ages of 22 and 70Have been diagnosed with depression and are currently experiencing a depressive episode for at least 12 monthsHave tried at least 4 different treatments without successAre willing and able to attend regular study visits at the IU Health Neuroscience Center in Indianapolis, IN over the course of 3 years