Still searching for relief from depression?  Have you tried multiple treatments for depression without success? You may have another option. When treatments haven’t worked, research may offer a new path. The Abbott TRANSCEND study is a research study for adults with depression who have not felt better after trying at least four different antidepressant medications. The purpose of the study is to learn how safe and effective a treatment called deep brain stimulation (DBS) may be for people with treatment-resistant depression. DBS uses a medical device made by Abbott to deliver gentle electrical signals to specific areas of the brain. This treatment is still being studied and is not yet approved for this use.You may qualify to join this study if you:Are between the ages of 22 and 70Have been diagnosed with depression and are currently experiencing a depressive episode for at least 12 monthsHave tried at least 4 different treatments without successAre willing and able to attend regular study visits at the IU Health Neuroscience Center in Indianapolis, IN over the course of 3 years

One Blood Sample. One Visit. A Big Impact.The Indiana Biobank is a research program that began in 2010 through the Indiana University School of Medicine and IU Health. You can think of it like a huge library—only instead of storing books, it stores more than 60,000 blood and other medical samples.Each sample is linked to a person’s medical records, but names and personal details are removed before researchers ever see them. This protects privacy while still allowing doctors and scientists to learn from the information.This particular study is part of the Biobank’s special collections for Alzheimer’s research.. It focuses on gathering blood samples from three groups of people:Individuals with Alzheimer’s disease (AD),Individuals with cognitive impairment, andHealthy adults (known as “controls”)By studying these samples, scientists can make sure that Alzheimer’s-related blood tests give consistent, reliable results no matter which lab looks at them. This is an important step toward improving how we diagnose and understand Alzheimer’s disease.More information about the Indiana Biobank, as well as FAQs, can be found here:  https://iuhealth.org/find-medical-services/indiana-biobank

We are looking for people of all ages, regardless of health condition, to take part in a study that is looking for new treatments for bone and muscle disorders.Bone and muscle disorders are the leading cause of disabilty in the United States. Researchers want to find out more about how people are affected by aging, injury, disease and illness. Your participation will help advance the diagnosis and treatment of bone and muscle disorders.

Why is this study being done?The purpose of this study is to understand how movement and sensory characteristics (e.g., posture, walking, hand and arm based reaching) present in psychotic disorders over time. Who can take part?We are looking for healthy individuals, ages 18-55, who have never been diagnosed with psychosis.

Why is this study being done?The purpose of this study is to understand how movement and sensory characteristics (e.g., posture, walking, hand and arm based reaching) present in psychotic disorders over time.   Who can take part?We are looking for individuals, ages 18-55, who have been diagnosed with Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder, or any other type of psychotic disorder.