Health Research
and Clinical Studies

All IN for Health provides a list of hundreds of active health studies happening right here in Indiana. These health studies are conducted by faculty at Indiana University, Purdue University, and the University of Notre Dame.

All IN for Health provides a list of hundreds of active health studies happening right here in Indiana. These health studies are conducted by faculty at Indiana University, Purdue University, and the University of Notre Dame.

Browse by Featured categories

Aging
Children, Families & Pregnancy
Dental
Online
Alcohol, Tobacco, and Substance Use
Alzheimer’s Disease & Dementia
Asthma,Lungs & Allergies
Bones, Muscles and Joints
Brain, Spine & Nervous System
Covid-19 & Infectious Disease
Diabetes, Heart and Blood Vessels
Digestive System (GI), Bowel & Liver
Health Mental, Behavioral Health & Developmental Conditions
Healthy Volunteer
Cancer
Diet, Nutrition, Exercise, & Sleep

Browse by Featured categories

Aging
Children, Families & Pregnancy
Dental
Online
Alcohol, Tobacco, or Other Substance Use
Alzheimer’s Disease & Dementia
Asthma,Lungs & Allergies
Bones, Muscles and Joints
Brain, Spine & Nervous System
Covid-19 & Infectious Disease
Diabetes, Heart and Blood Vessels
Digestive System (GI), Bowel & Liver
Health Mental, Behavioral Health & Developmental Conditions
Healthy Volunteer
Cancer
Diet, Nutrition, Exercise, & Sleep

Browse by Featured categories

Aging
Alcohol, Tobacco and Substance Use
Brain, Spine and Nerves
Cancer
Diabetes
Diet, Exercise and Nutrition
Healthy Volunteers
Mental and Behavioral Health
Alzheimer’s Disease and Dementia
Autoimmune Disease
Bladder and Kidneys
Bones, Muscles and Joints
Community and Environmental Health
Dental
Eye Conditions
Genetic and Rare Conditions
GI, Liver and Pancreas
Hearing, Speech and Language
Heart Health
Infectious Disease
Lungs, Asthma and Allergies
Maternal, Infant and Child Health
Online Studies
Public Health Studies
Skin and Wounds
Sleep
Surgery, Transplant and Imaging
Thyroid, Hormones and Metabolism

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Help Shape the Future of Health
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By donating a small blood sample, you can help researchers discover better treatments and improve health across Indiana.

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All IU Health Patients of Any Age

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By taking part, you're helping improve care for you, your loved ones, and people across Indiana.

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Browse studies by

Recently added/updated trials

Purdue University Study on PFAS and Brain Activity

D
Dan Foti
18 years - 30 years
Accepts healthy volunteer
All genders
The PACER Lab at Purdue University is looking for volunteers age 18-30 years old for a study on PFASand brain activity (PI: Dr. Dan Foti, IRB protocol IRB-2023-1271).

Prospective Evaluation of Venous Congestion Using the Venous Excess Ultrasound Score (Vexus) During Early Fluid Resuscitation in Adult Patients With Major Burns

S
Sunnie Wong
18 years - 100 years
All genders
Observational
This study aims to prospectively characterize venous congestion during early burn resuscitation by use of ultrasound and evaluate its relationship to traditional resuscitation metrics.THIS STUDY IS ENROLLING BY INVITATION ONLY - Potential subjects will be identified by the investigators by EMR review of burn ICU admissions. The investigators will meet with the patient inside their private hospital room and will discuss the study with the patient. All potential subjects that meet inclusion criteria and do not meet exclusion criteria will be approached for potential participation.

Reducing Risk of Dementia through Deprescribing: Cognitive Outcomes After AntiCholinergic Reduction (R2D2: COACH)

M
Malaz Boustani, MD
65 years or above
All genders
A cluster-randomized controlled trial (RCT) called "Reducing Risk of Dementia through Deprescribing" (R2D2) to evaluate the impact of a deprescribing intervention on important cognitive and safety outcomes.  This study will evaluate the effects of the use of a program to reduce prescribing of a group of commonly prescribed medications called anticholingerics that may adversely effect cognitive functioning in older adults. THIS STUDY IS ENROLLING BY INVITATION ONLY - ResNet data managers will identify physicians from the medical records of Community Health Network, and these participating physicians' patients will be approached for recruitment.' They may be contacted by phone or during clinic visits upon referral from physician.  Physicians agreeing to participate in the study will be randomized to intervention or usual care in random blocks of two or four and stratified by clinic site. Physician randomization status will determine participants’ study groups. Physicians randomized to usual care will not have access to the intervention. Physicians are not the subjects of the study. The subjects are the patients of the physicians. Physicians will not be aware of how or when their patients are being recruited or for what studies they will be offered.

A Randomised, Double-Blind, Placebo-Controlled Trial with an Open-Label Extension to Assess the Pharmacokinetics, Safety, and Efficacy of Empagliflozin Tablets in Paediatric Patients with Chronic Kidney Disease (Empa-Kidney Kids)

M
Myda Khalid
2 years - 17 years
All genders
Interventional
This study is open to children aged 2 to 17 with chronic kidney disease (CKD). The purpose of this study is to find out if a medicine called empagliflozin helps children and adolescents with CKD. Other goals of the study are to find out how empagliflozin is tolerated and handled by the body in children and adolescents with CKD.THIS STUDY IS ENROLLING BY INVITATION ONLY

A Phase 2, Multicenter, Randomized, Placebo-Controlled, Double-Blind Study of the Efficacy and Safety of Vamifeport in Adult Subjects with Hfe-Related Hereditary Hemochromatosis

E
Eric Orman
18 years - 100 years
All genders
Phase 2
Interventional
This is a phase 2, multicenter, randomized, placebo-controlled, double-blind, parallel-group, proof-of-concept study to assess vamifeport in adult participants with homeostatic iron regulator gene-related hereditary hemochromatosis (HFE-HH). The primary objective of the study is to assess the effect of vamifeport treatment on magnetic resonance imaging (MRI)-based liver iron concentration (LIC) in adult participants with HFE-HH.THIS STUDY IS ENROLLING BY INVITATION ONLY
 Discover a New Path to Hope: Join a Study That’s Working to Improve Care for Depression

Discover a New Path to Hope: Join a Study That’s Working to Improve Care for Depression

S
Steve Strakowski
18 years - 75 years
All genders
Interventional
Take the First Step Toward Feeling Better—Join Our Depression Study Today!Living with depression can feel heavy, even on your best days.  If you’re looking for new options—or simply wondering what else might help—you’re not alone. This research study is exploring a possible new treatment for major depression, and you may be able to take part. Your experience could help bring new hope to you and others who face depression every day.We’re looking for people like you to help us learn about brenipatide, a new medicine that might help with major depressive disorder (MDD).  In this study, we want to learn more about the safety and effectiveness of brenipatide and if it can help lower your depression symptoms and keep them from coming back.This study may be a good fit for you if:You have been diagnosed with major depressive disorder (MDD).You are taking a stable depression medicine.You do not have type 1 diabetes, recent substance use problems, or certain other mental health conditions.You can attend study visits at the IU Health Neuroscience Center in Indianapolis, IN and follow simple study steps, like giving yourself injections and filling out short logs or questionnaires.
 Share Your Wisdom: Help Us Improve Online Health Tools For Older Adults

Share Your Wisdom: Help Us Improve Online Health Tools For Older Adults

K
Krista Hoffmann-Longtin
65 years or above
Accepts healthy volunteer
All genders
Phase 1
Do you find using the internet and technology confusing?  Is it difficult for you to find the health information that you need online? Do you find it difficult to use technology to seek healthcare?YOUR EXPERIENCE WITH HEALTH TECHNOLOGY MATTERS.  That is why this study is focused on learning how older adults use technology to manage their healthcare and how they feel about it. We want to hear about your experiences and see if using simple stories and everyday examples can help make health technology easier to understand and use.By sharing your thoughts and experiences, you can help us in making health technology easier for everyone. You may qualify to join this study if you are 65 years of age or older and live in the Indianapolis, IN metro area.
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Online study