Health Research
and Clinical Studies

All IN for Health provides a list of hundreds of active health studies happening right here in Indiana. These health studies are conducted by faculty at Indiana University, Purdue University, and the University of Notre Dame.

All IN for Health provides a list of hundreds of active health studies happening right here in Indiana. These health studies are conducted by faculty at Indiana University, Purdue University, and the University of Notre Dame.

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Browse by Featured categories

Aging
Children, Families & Pregnancy
Dental
Online
Alcohol, Tobacco, or Other Substance Use
Alzheimer’s Disease & Dementia
Asthma,Lungs & Allergies
Bones, Muscles and Joints
Brain, Spine & Nervous System
Covid-19 & Infectious Disease
Diabetes, Heart and Blood Vessels
Digestive System (GI), Bowel & Liver
Health Mental, Behavioral Health & Developmental Conditions
Healthy Volunteer
Cancer
Diet, Nutrition, Exercise, & Sleep

Browse by Featured categories

Aging
Alcohol, Tobacco and Substance Use
Brain, Spine and Nerves
Cancer
Diabetes
Diet, Exercise and Nutrition
Healthy Volunteers
Mental and Behavioral Health
Alzheimer’s Disease and Dementia
Autoimmune Disease
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Help Shape the Future of Health
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By donating a small blood sample, you can help researchers discover better treatments and improve health across Indiana.

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All IU Health Patients of Any Age

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By taking part, you're helping improve care for you, your loved ones, and people across Indiana.

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Browse studies by

Recently added/updated trials

Respiratory and Real-Time Dynamics in Exercise-Induced Paradoxical Vocal Fold Motion

R
Rita Patel, PhD
18 years - 26 years
Accepts healthy volunteer
All genders
The purpose of this study is to determined the effectiveness of the new wearable neck device to accurately identify Exercise-Inducible Laryngeal Obstruction (EILO) in the field setting. Additionally, the purpose of this study is to identify the cause and changes in size of the face and the neck of EILO and determine which exercise is most beneficial for relieving EILO.THIS STUDY IS ENROLLING BY INVITATION ONLY - Participants may be recruited from the following:  the IU Health Voice Center, clinical practices of the investigators, physician referrals, posting of study information at the EILO global forums, and other methods. For investigator-initiated methods, the potential subjects will be contacted via phone and/or email. 

Prevalence of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) in High-Risk Patients Presenting to Primary Care

R
Raj Vuppalanchi, MD
40 years or above
All genders
Observational
This study will provide the first comprehensive real-world prevalence data on MASLD in a primary care-based high-risk population, using validated non-invasive imaging. Results will inform evidence-based screening guidelines, support integration of FibroScan into PCP workflows, and facilitate early intervention to reduce progression to advanced liver disease. Identified predictors of significant fibrosis will aid in prioritizing referral pathways and health system resource allocation.THIS STUDY IS ENROLLING BY INVITATION ONLY - Prospective participants meeting study criteria and presenting to a PCP visit will be approached during their clinic appointment in a private room about participating in the study. 

Efficacy And Safety Of Medtronic 780G Automated Insulin Delivery System In Adults With Type 1 Diabetes And Gastroparesis

V
Viral Shah
18 years - 100 years
All genders
Interventional
The primary objective of this research is to study efficacy of Medtronic 780 G system in patients with type 1 Diabetes and gastroparesis (slow gastric emptying) compared to usual care (either multiple daily insulin injections or non Medtronic insulin pump therapy).THIS STUDY IS ENROLLING BY INVITATION ONLY - Study team will review GI and Endo clinic patient lists to see if they have type 1 diabetes and gastroparesis. Subjects will be contacted and recruited from Endocrinology and GI group by the study team.

Co-Design of Patient Experience Survey

D
Diane Kuhn
18 years - 100 years
Male
Observational
We will conduct a co-design session with approximately 6-12 patients to improve the design of patient experience surveys. We plan to recruit patients who are underrepresented in survey completion to contribute to development.THIS STUDY IS ENROLLING BY INVITATION ONLY - Research coordinator/technician will review the ED tracking board to determine patients who meet eligible criteria for the study. Patients will be approached at the time of discharge from the ED and provided information about the study in their private room. We will review inclusion/exclusion criteria and they will have the option to consent to participation. 
 A Phase 2, Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study to Evaluate the Safety and Efficacy of Aga2115 in Adults With Type I, Iii, or Iv Osteogenesis Imperfecta (Oi)

A Phase 2, Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study to Evaluate the Safety and Efficacy of Aga2115 in Adults With Type I, Iii, or Iv Osteogenesis Imperfecta (Oi)

E
Erik Imel, MD
18 years - 75 years
All genders
Phase 2
Interventional
This study will determine the effect of treatment of AGA2115 in adults with Type I, III, or IV osteogenesis imperfecta versus placeboTHIS STUDY IS ENROLLING BY INVITATION ONLY

Prospective Assessment of Health-Related Quality of Life and Caregiver Burden in Children and Parents of Children with Lower Urinary Tract Dysfunction with Validation of the Riley Bladder Quality of Life Questionnaire (RiBQQ)

N
Nikhil Batra
8 years - 17 years
All genders
Observational
This is a prospective study to assess both validated and non-validated questionnaires and quality of life tools in children with LUTD. Additionally, we will obtain data from parents/guardians of children with LUTD and parents/guardians of children without LUTD to assess health care burden of LUTD.THIS STUDY IS ENROLLING BY INVITATION ONLY - The study is open to patients being assessed by a urology provider after often waiting months with chronic urinary problems which primarily affect quality of life (the subject of this study) and not physical health. Subjects will be identified during clinic visits from the medical record, clinic schedules, or provider recommendation. A researcher/physician/NP will provide study information during the clinic visit and a brief description of the study or a researcher will call subjects by phone to introduce study and obtain email for sending additional information.In clinic: A research team member will approach eligible families as early as possible about a study for their consideration. This may occur shortly after check-in (while in the waiting room) or when brought into a room.
 Together for Tomorrow: Explore New Treatment Options for Lung Cancer

Together for Tomorrow: Explore New Treatment Options for Lung Cancer

V
Vijaya L. Kakani, MD
18 years - 100 years
All genders
Phase 3
Interventional
We understand that living with non-small cell lung cancer (NSCLC), especially with the KRAS G12C mutation, can be incredibly challenging.   Many people with lung cancer go through hard treatments and tough side effects. That's why we're inviting adults (ages 18 and older) who have advanced or metastatic nonsquamous NSCLC to participate in our study.  The goal is to find out if a investigational combination of targeted therapy and immunotherapy can help you live longer without your cancer growing or spreading as compared to traditional chemotherapy treatment.We're also hoping that this study helps us find ways to:Slow down cancer growthUse treatments that target cancer more directlyLearn if fewer or different side effects are possibleImprove quality of lifeParticipating in this study offers you a chance to explore new treatment options while helping researchers learn more about effective therapies for lung cancer. If you want to make a difference for yourself and others, consider joining us.