Featured Clinical Studies
Quality of Life and Heart Failure Study
Share Your Story and Support Research That Helps People Live Better Lives with Heart Failure.Living with heart failure can be hard. You may deal with pain, tiredness, and daily challenges that affect how you feel and live your life. This study is here to better understand those experiences—and your voice …
Soccer Players, Keep Your Head in the Game—Join Our Brain Impact Recovery Study
We are conducting a study to see if fish oil, which contains omega-3 fatty acids like DHA and EPA, can protect soccer players' brains from repetitive head impacts. Our main goal is to determine if these omega-3s can have possible protective effects from repeated repetitive head impacts, which could lead …
ARE YOU PREGNANT OR A NEWLY EXPECTING MOM? JOIN THE HEARTLAND STUDY!
DID YOU KNOW? Herbicides are widely used in the Heartland, and farmers are using these chemicals more than ever before. Several studies have raised concern that some of the herbicides may be associated with reproductive disorders, certain birth defects, and developmental disorders. What are herbicides? Herbicides are a type of pesticide that …
Caring for Caregivers: Join our study!
Caring for Someone Else? Caring for Others Starts With Caring for Yourself. Caring for someone with Alzheimer’s disease or related dementia is important work—but it can also be stressful and exhausting. Many caregivers, put their own health last. As a caregiver, you deserve care, too. Our study is about supporting …
Rural Indiana Residents Needed for Gut Health Study
Have you ever wondered how things you eat or drink affect the bacteria in your gut? Do you live in a rural Indiana area? Researchers from the Department of Nutrition Science at Purdue University are looking at a how nutrient called cysteine [pronounced SIS-tee-een] is related to bacteria in our …
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Help Shape the Future of Health
with the Indiana Biobank
By donating a small blood sample, you can help researchers discover better treatments and improve health across Indiana.
Who Can Join?
All IU Health Patients of Any Age
What Is Involved?
It's easy-we collect a blood sample during your regular doctor visit.
Why does it Matter?
By taking part, you're helping improve care for you, your loved ones, and people across Indiana.
Recently added/updated trials
Prospective Sample Collection Of Subjects For The Development Of Multiple Immunosuppressant Therapeutic Drug Monitoring Assays
A
Asif Sharfuddin
The primary aim of this study is to collect biological samples that may be used in the development of future multi-drug immunosuppressant therapeutic drug monitoring assays in solid organ transplant recipients.THIS STUDY IS ENROLLING BY INVITATION ONLY - The Investigator will collect samples from up to 3,000 adult subjects who have undergone a kidney, heart, or liver transplant and are currently prescribed Cyclosporine, Tacrolimus, Everolimus, Sirolimus, or Mycophenolic Acid (MPA) as part of their transplant care plan.
A Phase 3, Randomized, Double-Blind, 48-Week Placebo-Controlled Study to Assess the Efficacy, Safety, and Tolerability of Dyne-101 Administered to Participants with Myotonic Dystrophy Type 1
L
Laurie Gutmann
This Phase 3 study was designed based on the results of ACHIEVE. It is a randomized,double-blind study with a 48-week Placebo-Controlled Period to assess the efficacy, safety,and tolerability of DYNE-101 administered IV to participants with DM1 aged ≥16 years.This study is adequately powered to evaluate the effect of DYNE-101 50 mg/kg administeredQ8W compared to placebo on the primary efficacy endpoint of change from baseline in the5 times sit-to-stand (5×STS) test at Week 49 and address the significant unmet need for a safeand effective disease-modifying therapy to treat DM1.THIS STUDY IS ENROLLING BY INVITATION ONLY
Feasibility and Potential Efficacy of High-Intensity Gait Training in Individuals with Cerebellar Damage
T
T. George Hornby
The primary objective of this study is to determine the preliminary feasibility and safety of high intensity stepping training for individuals with chronic (>6 months) cerebellar damage. Additionally, the secondary aim of this study is to assess the comparative efficacy of high intensity stepping training and conventional training on locomotor recovery, specifically walking endurance.To date, no studies have attempted to maximize both the amount and cardiovascular intensity of stepping practice in patients with cerebellar disorders.THIS STUDY IS ENROLLING BY INVITATION ONLY - Recruitment will occur primarily from the inpatient and outpatient rehabilitation centers of the Rehabilitation Hospital of Indiana, with secondary sources of recruitment from surrounding rehabilitation facilities via flyers/laboratory contact information provided to associated clinical staff and providers.
Are You Caring For A Loved One With Cancer? We’d Love To Hear From You
V
Victoria Champion
Help us learn how to better support rural families facing cancer. Take part in this study and help improve care for caregivers like you. Caregivers play a vital role in helping cancer patients get the best possible care. But caregiving—especially in rural communities—can be demanding and emotionally overwhelming. Many caregivers face challenges related to stress, mental health, and balancing complex at‑home treatment responsibilities. Rural caregivers often face additional barriers such as fewer local resources and longer travel distances for care.That is why researchers at Indiana University are looking to speak with caregivers of people with solid tumor cancers who live in rural areas of Indiana.Your experiences matter. By sharing your story, you can help shape better care for other caregivers and the people they love.
Tooth Wear & Sensitivity Study
A
Anderson Hara, DDS
Join a short, one-visit dental study! Your experience can improve dental care for adults and help us learn why teeth become worn or sensitive over time.We’re doing a study to learn how common tooth wear and tooth sensitivity are in adults across the U.S. We’ll also check for receding gums and other small changes around the teeth, and compare our results with studies from other countries.We are looking for adults (ages 18+), in generally good health, to complete a short questionnaire, have their teeth scanned, and take a simple tooth-sensitivity test during a single study visit.
Better Sleep, Brighter Minds: Exploring Relaxation for Youth Ages 11-13
H
Heather Hardin
JOIN the study!The purpose of this study is to try out a new way of teaching kids and parents ways to relax and sleep skills to see if it helps youth with sleep and well-being.The study tasks can be completed entirely online (NO in-person visits required).Who can take part?Youth (ages 11-13) who are experiencing mild stress symptoms and a parent. In order to be eligible, parents/caregivers and children must both participate in the research study.
Mmmm! I'm All IN for Kidney Health! Join Our Chronic Kidney Disease and Diet Study Contact List
S
Sharon Moe, MD
What you eat matters when you have chronic kidney disease (CKD)—and researchers want to learn what works best.The IU School of Medicine is studying how diet affects kidney health and invites people with CKD to join a nutrition research contact list. By signing up, you’ll be notified about studies that may be a good fit for you.Joining the contact list is easy and low‑commitment. You’re simply giving permission to be contacted—you can always decide whether or not to take part in a study.Your interest helps researchers learn more, improve nutrition guidance, and support better kidney health for people across Indiana.
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