The purpose of this study is to evaluate the technical and operational performance of Lovelace in comparison with the clinical standard-of-care CTG for antepartum fetal monitoring (i.e. NST), and to collect evidence of its safety. The main objective is to evaluate the safety and performance of Lovelace for antepartum monitoring in pregnant women at gestational ages of 32 weeks or greater, in comparison with the standard- of-care CardioTocoGraph (CTG).THIS STUDY IS ENROLLING BY INVITATION ONLY - This study is enrolling pregnant women of 18 years of age, or older, at the time of consent, with a singleton pregnancy, and with the gestational age of 32 weeks or above. Potential participants will be invited to participate by the study team.

INHALE-1st is a Phase 2, single-arm, multi-center, clinical study evaluating the safety and efficacy of Afrezza in combination with subcutaneously-injected basal insulin (BI) for youth 10 to THIS STUDY IS ENROLLING BY INVITATION ONLY 

This phase I trial studies the side effects and best dose of trametinib and everolimus ing pediatric and young adult patients with gliomas that have come back (recurrent). Trametinib acts by targeting a protein in cells called MEK and disrupting tumor growth.verolimus is a drug that may block another pathway in tumor cells that can help tumors grow. Giving trametinib and everolimus may work better to treat low and high grade gliomas comparedb or everolimus alone.THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not actively “recruited,” but are screened by their physician for appropriate clinical trial(s) at the time of their routine clinic visit. Occasionally, a patient may be a self-referral or physician referral, but are still screened for appropriate clinical trials at the time of their routine clinic visit. PI and staff may send copies of relevant consent forms to these patients to look over prior to actually consenting or enrolling them. This may take place at the patient's visit at which the consent is presented or the patient's next visit to the outpatient hematology/oncology clinic. Interested in participating? For more information about this research study or other cancer-related clinical trials at IU Simon Comprehensive Cancer Center, please contact:IU Clinical Trials Office Email: iutrials@iu.edu Phone: (317) 278-5632

The purpose of this study is to find out whether certain genetic differences may explain why some severely burned patients continue to have high lactic acid levels in their blood even after receiving proper medical treatment. We will collect a small blood sample from each patient and analyze their DNA to look for gene variations related to how the body produces energy. Understanding this may help doctors better predict which patients are at higher risk and develop more personalized treatments in the future.THIS STUDY IS ENROLLING BY INVITATION ONLY - Burn patients with TBSA equal to or greater than 20% will be identified by burn unit team on the burn service, this is comprised of attending, APPs, and fellow. Patients with TBSA of 20% or greater will have the resuscitation protocol activated, and resuscitation will be followed with serial lactate. Response to resuscitation will be assessed with multiple parameters, including lactate, urine output, and overall clinical status. Once these patients are identified, they will be approached by the team, and the research study will be discussed with them. If they are intubated or not in a state to provide consent due to critical clinical condition, the study will be discussed with LAR who will sign on patient's behalf. This will be done in person.