DID YOU KNOW?... Colorectal cancer(CRC) is the second leading cause of cancer death in the United States. CRC is a serious health problem in the U.S., and African American/Black individuals are affected more than others.  What is this study about?This study will look at a nutrient called cysteine. We think that factors like a person’s diet and stress levels can affect how cysteine breaks down in the gut. We want to see how this can impact a person’s risk of CRC. To find out, we will study the foods people eat and their stress levels.  Who can take part?Adults aged 45-75 who are considered to be at high risk of developing colorectal cancer (have a history of polyps) and have no food allergies, dietary restrictions, or therapeutic diets. 

What is the purpose of this study?Social determinants of health are nonmedical factors that influence health outcomes. Adverse social determinants of health negatively affect high risk populations who are at greater risk of dementia and other medical diseases. Just as important is the concerning fact that these high risk populations often do not take part in research studies that look to create treatments for Alzheimer’s disease and related dementias. This is why the Indiana University School of Medicine Department of Neurology in collaboration with the Indiana Alzheimer’s Disease Research Center look to understand what the barriers are that diminish engagement with research, as well as motivating factors to participate in a study. This understanding will help us develop strategies that will increase interest levels in research participation and eventually develop new therapies for Alzheimer’s disease.¿Cuál es el propósito de este estudio?Los determinantes sociales de la salud son factores no médicos que influyen en los resultados de salud. Estos determinantes afectan negativamente a las poblaciones de alto riesgo, que presentan un mayor riesgo de demencia y otras enfermedades. Igualmente importante es el preocupante hecho de que estas poblaciones de alto riesgo a menudo no participan en estudios de investigación que buscan desarrollar tratamientos para la enfermedad de Alzheimer y las demencias relacionadas. Por ello, el Departamento de Neurología de la Facultad de Medicina de la Universidad de Indiana, en colaboración con el Centro de Investigación de la Enfermedad de Alzheimer de Indiana, busca comprender las barreras que disminuyen la participación en la investigación, así como los factores que motivan la participación en un estudio. Este conocimiento nos ayudará a desarrollar estrategias que aumenten el interés en la participación en la investigación y, con el tiempo, desarrollen nuevas terapias para la enfermedad de Alzheimer.