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Recently added/updated trials
Attention in Aphasia Study
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Arianna LaCroix
Why is this study being done?Researchers at Purdue University are recruiting for a study that examines how thinking and language change after having a stroke or other brain injury. We are investigating how different types of attention contribute to producing and understanding sentences. Who can take part?Adults (ages 18 or older) who have aphasia following a stroke or other brain injury (TBI, viral infection, tumor, etc.)
Indiana Memory and Aging Study (IMAS)
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Andrew Saykin, PsyD
The purpose of this study is to use brain imaging and genetic biomarkers, cognitive and sensory testing and behavior ratings to study memory processing as it relates to aging in the brain.
Lend Your Ears (and Brains) For Hearing Research!
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Michael Heinz
Why is this study being done?The purpose of this study is to better understand how our ears and brains help us perceive the world around us. In particular, we are interested in understanding how our senses allow us to have conversations in complex environments such as crowded restaurants and busy streets. We are collecting hearing information from a large number of participants so that we can pinpoint what factors contribute to individual differences in hearing ability.Who can take part?ANYONE who is 18 years of age or older, regardless of health condition, is invited to participate.
High vs low-frequency of high-intensity training in chronic stroke: a pilot randomized trial
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T. George Hornby
What is the purpose of this study?The purpose of this study is to investigate the effectiveness of two different frequencies of physical therapy sessions on the recovery of mobility, function, and other measures of health in individuals more than 6 months following stroke. THIS STUDY IS ENROLLING BY INVITATION ONLY - Physical therapists and physicians treating patients post-stroke both at the Rehabilitation Hospital of Indiana and surrounding rehabilitation facilities will be made aware of this study and may refer patients to our study by providing the flyer or laboratory contact information. Other sources of recruitment include flyers posted at the Rehabilitation Hospital of Indiana and provided to physical therapists and physicians in the surrounding area which may be distributed to participants. Members of the study team may also review medical records of Rehabilitation Hospital of Indiana patients to identify and contact potential subjects.
ADULTS NEEDED FOR DEPRESSION STUDY!
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Susan Conroy, MD PhD
DO YOU OR SOMEONE YOU KNOW HAVE DEPRESSION? Join Our Study and Help Researchers Discover A New Treatment For Treatment-Resistant Depression! Researchers at Indiana University School of Medicine are looking for adults to take part in a study to learn more about the effects of repetitive Transcranial Magnetic Stimulation (rTMS) treatments at the middle of the forehead on symptoms of depression and brain function. rTMS is a non-invasive method of stimulating the brain and changing the way the parts of your brain communicate with each other.Results from this study will help us better understand the nature of the disorder with the goal of improving ways to prevent, diagnose, and treat Depression.
Measuring Allostatic Load in a Pregnant Cohort
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Jasmine D Johsnon
What is the purpose of this study?Our central hypothesis is that structural and personally-mediated racism and its association with adverse pregnancy outcomes can be measured. The overall objectives of this study are to measure the burden of racism in an obstetric population and its impact on preterm birth and hypertensive disease of pregnancy. THIS STUDY IS ENROLLING BY INVITATION ONLY - We will prospectively recruit birthing people who are receiving prenatal care in the Indiana University (IU) Health and Eskenazi Health systems. Members of the research team will identify potential participants in the medical record, confirm eligibility, and approach potential participants to recruit and consent in the outpatient prenatal care clinics.
Investigating the role of T2R38 taste receptors in influencing the susceptibility to Periodontitis
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Mythily Srinivasan
What is the purpose of this study?The aim of this study is to investigate and correlate the susceptibility of homozygous recessive genotype (AVI/AVI, non-taster) individuals to periodontitis. Using saliva collected from the subjects for research purposes and compared with periodontal examination results (standard of care), we hypothesize that individuals with T2R38 receptor non-taster (AVI/AVI) haplotype will exhibit increased severity of chronic periodontitis compared to those with taster (AVI/PAV) or super-taster (PAV/PAV) T2R38 haplotype. THIS STUDY IS ENROLLING BY INVITATION ONLY - Subjects will be recruited chairside by the research team during a scheduled visit to the Fritts clinic or Graduate Periodontics clinic. Those who express interest in the project will complete the consent process. The scheduled appointment will collect data needed for the study as standard of care.
