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Help Shape the Future of Health
with the Indiana Biobank
By donating a small blood sample, you can help researchers discover better treatments and improve health across Indiana.
Who Can Join?
All IU Health Patients of Any Age
What Is Involved?
It's easy-we collect a blood sample during your regular doctor visit.
Why does it Matter?
By taking part, you're helping improve care for you, your loved ones, and people across Indiana.
Recently added/updated trials
Exploring Treatment Options After Lung Cancer Surgery
V
Vijaya L. Kakani, MD
Do you have non-small cell lung cancer (NSCLC) but the cancer was not fully removed by surgery? You may qualify for a study exploring treatment options for NSCLC.This research study is testing whether adding a medication called sacituzumab tirumotecan to pembrolizumab after surgery may help prevent non-small cell lung cancer (NSCLC) from returning in people whose cancer was not completely removed by surgery. You may be able to take part if you:Are an adult diagnosed with non-small cell lung cancer (NSCLC)Have had surgery for NSCLCDid not have a complete response after surgeryAre eligible to receive pembrolizumab
Neonatal Caloric Absorption in Relation to Growth Outcomes and Nutrition
K
Katie Huff
The goal of this study is to learn more about how babies in the NICU are able to take in and use the food they are getting. We want to follow babies during their stay in the NICU and measure their input and output, essentially, what’s in their diet and what’s in their poop and urine, and what the impact is on their growth. THIS STUDY IS ENROLLING BY INVITATION ONLY - Infants admitted to the Riley Hospital or Eskenazi Neonatal Intensive Care Unit (NICU) will be screened for eligibility with pre-determined inclusion and exclusion criteria For infants who are eligible, the parents of the patient will be approached and informed consent will be obtained by research personnel. If mother is also providing breast milk, consent will be obtained regarding obtaining breast milk samples. Recruitment may occur in person or over the phone with information given about study.
Prebiotics in Women’s Health and Aging: The Gut-Bone Connection
B
Brenda Smith
What is the purpose of this study?Dietary supplementation with dried plums has been shown to reduce bone loss in women. The purpose of this research study is to understand how dried plums are doing this by studying the immune cell, gut microbe, and bone responses.Who can take part?Women between the ages of 60-75 years who are in generally good health.
Multimodal Fetal and Placental Imaging and Biomarkers of Clinical Outcomes in Opioid Use Disorder
R
Rupa Radhakrishnan, MD
Why is this study being done?This research study is being done to improve outcomes in mothers who have taken opioids during pregnancy and their newborn babies. We want to learn more about how the placenta functions and how the fetal brain develops when exposed to opioids. We also want to learn if there are any long-term effects on newborn babies, compared to babies whose mothers did not take opioids during pregnancy. We want to follow mothers and babies over approximately one year to look at genetic, social, environmental, and psychological reasons that affect mothers who take opioids and their babies. Who can take part?Women who are 16-32 weeks pregnant and/or have been referred by the pregnancy . We are interested in following participants from pregnancy through the child’s 1st year of life. . Additional informationStudy title: Multimodal Fetal and Placental Imaging and Biomarkers of Clinical Outcomes in Opioid Use DisorderThe study is being conducted by Dr. Rupa Radhakrishnan, MS, MD, with the Indiana University School of Medicine, Department of Radiology at Riley Hospital for Children. This study is being funded by the National Institutes of Health (NIH), specifically the National Institute of Drug Abuse (NIDA) and the Helping to End Addiction Long Term (HEAL) initiative. To learn more about Rupa Radhakrishnan and her research interests, please visit this link: https://medicine.iu.edu/faculty/38670/radhakrishnan-rupa
Clinical Evaluation of the i-STAT Crea, CG4+ and CG8+ Cartridges using Neonatal Capillary Whole Blood Specimens with the i-STAT 1 Analyzer
T
Thomas E. Davis
The purpose of this voluntary research study is to collect and test heel stick blood samples from neonates either to compare the performance of tests on the i-STAT Crea, CG4+, or CG8+ cartridges to the performance of the same tests with an FDA-cleared device, or to evaluate the precision (accuracy) of the tests. THIS STUDY IS ENROLLING BY INVITATION ONLY - IU IVD research staff will recieve physician referrals and/or identify potentially eligible neonates (from birth to 28 days of age) who will have measurable levels of the analytes measured by the i-STAT Crea, CG4+, CG8+ cartridge in their blood as part of their normal medical care in order to collect source capillary specimens samples from via heel-stick.
Finder G6Pd Test Migration to New Finder Instrument Model - Performance Evaluation Protocol
T
Thomas E. Davis
The purpose of this study is to confirm that the FINDER G6PD Test works the same on a new version of the FINDER instrument. G6PD (glucose-6-phosphate dehydrogenase) is an enzyme that helps red blood cells function properly. When someone doesn’t have enough G6PD, it can lead to hemolytic anemia—a condition where red blood cells break down faster than the body can replace them. Because red blood cells carry oxygen, this can cause symptoms like tiredness, weakness, or shortness of breath.THIS STUDY IS ENROLLING BY INVITATION ONLY
A Phase 3, Multicenter, Prospective Open-Label Study to Evaluate the Diagnostic Performance of [18F]Fapi-74 Pet/Ct for the Detection of Metastatic Disease in Adults with Pancreatic Ductal Adenocarcinoma
C
Cindy Yuan
This is a multi-site, open-label, non-randomized, single dose study to assess the clinical utility of [¹⁸F]FAPI-74 PET/CT in the detection of metastatic disease in individuals with pathologically confirmed pancreatic ductal adenocarcinoma. THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not actively “recruited,” but are screened by their physician for appropriate clinical trial(s) at the time of their routine clinic visit. Occasionally, a patient may be a self-referral or physician referral, but are still screened for appropriate clinical trials at the time of their routine clinic visit. PI and staff may send copies of relevant consent forms to these patients to look over prior to actually consenting or enrolling them. This may take place at the patient's visit at which the consent is presented or the patient's next visit to the outpatient hematology/oncology clinic. Interested in participating? For more information about this research study or other cancer-related clinical trials at IU Simon Comprehensive Cancer Center, please contact:IU Clinical Trials Office Email: iutrials@iu.edu Phone: (317) 278-5632
