Health Research
and Clinical Studies

All IN for Health provides a list of hundreds of active health studies happening right here in Indiana. These health studies are conducted by faculty at Indiana University, Purdue University, and the University of Notre Dame.

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All IN for Health provides a list of hundreds of active health studies happening right here in Indiana. These health studies are conducted by faculty at Indiana University, Purdue University, and the University of Notre Dame.

Learn more

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Recently added/updated trials

Non-Inferiority Study of Erector Spinae Plane Block Compared to Thoracic Epidural in Pain Management of Rib Fractures

18 years or above
Accepts healthy volunteer
All genders
The purpose of this study is to compare 2 pain control treatments for people with 3 or moreb fractures.
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A Randomised, Double-blind, Placebo-controlled, Parallel Group, Multicentre, Phase III Study to Evaluate the Efficacy and Safety of Tezepelumab in Adult Participants with Moderate to Very Severe Chronic Obstructive Pulmonary Disease (JOURNEY)

M
Marc Rovner
18 years - 100 years
All genders
Phase 3
Interventional
The purpose of this study is to compare the effect of tezepelumab with placebo on moderate or severe COPD exacerbations in participants with moderate to very severe COPD. THIS STUDY IS ENROLLING BY INVITATION ONLY
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Evaluation of the Performance of Bd Bactectm Fxi Culture System Vs Bd Bactectm Fx in the Detection of Bloodstream Infections

C
Christopher Emery, MD
18 years or above
All genders
Interventional
This study will be conducted to demonstrate the safety and efficacy of the BACTEC FXI Culture System as compared to the BACTEC FX for blood samples. Although the protocol references pediatric sample collection, our site will only be enrolling subjects 18 years of age or older.THIS STUDY IS ENROLLING BY INVITATION ONLY - Eligible participants will be identified by emergency room staff through screening for patients who have received a blood culture order due to a suspected Blood Stream Infection (BSI). 
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Integrated Therapies for Alcohol Use in Alcohol-Associated Liver Disease

R
Raj Vuppalanchi, MD
18 years - 100 years
All genders
Interventional
To determine whether interventions directed to treat AUD integrated with sAH therapies will improve a composite endpoint of alcohol and liver-related events at 6 months compared to usual care for AUD (primary endpoint)To compare 90-day survival in patients receiving F-652 with those receiving up to 28 days of prednisone using the Day-7 Lille score as a stopping rule (secondary endpoint)To compare one-year overall survival in patients receiving either IL-22 or prednisone with or without acamprosate (secondary endpoint).THIS STUDY IS ENROLLING BY INVITATION ONLY - Patients admitted to the hospital with a clinical diagnosis of severe AH that are eligible for steroids will be identified and contacted by the study team about participating.
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Rural Indiana Caregivers Needed - Help Us Test a Smartphone App

Rural Indiana Caregivers Needed - Help Us Test a Smartphone App

R
Richard Holden
18 years or above
Accepts healthy volunteer
All genders
Are you a caregiver of someone with memory loss, dementia, or Alzheimer’s disease AND you live in a rural area of Indiana? Join our study!Our study is looking at how a smartphone app can help caregivers of dementia patients.  The app is designed for people living in rural areas to support caregivers in managing the challenges associated with dementia care. Your participation could help us see if the app can lessen caregivers' stress and improve the health of dementia patients.We are inviting adults (ages 18 and older living in rural Indiana who are caring for someone with dementia and are able to use a smartphone to participate.Participants will complete all study tasks from home, with no in-person visits required. 
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Online study
Indiana Memory and Aging Study (IMAS)

Indiana Memory and Aging Study (IMAS)

A
Andrew Saykin, PsyD
65 years - 100 years
Accepts healthy volunteer
All genders
The purpose of this study is to use brain imaging and genetic biomarkers, cognitive and sensory testing and behavior ratings to study memory processing as it relates to aging in the brain.
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Observation or Radiation Therapy in Treating Patients With Newly Diagnosed Grade II Meningioma That Has Been Completely Removed by Surgery

18 years or above
All genders
Phase 3
Interventional
This randomized phase III trial studies how well radiation therapy works compared with observation in treating patients with newly diagnosed grade II meningioma that has been completely removed by surgery. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors.
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