Featured Clinical Studies
Are You Caring For A Loved One With Cancer? We’d Love To Hear From You
Help us learn how to better support rural families facing cancer. Take part in this study and help improve care for caregivers like you. Caregivers play a vital role in helping cancer patients get the best possible care. But caregiving—especially in rural communities—can be demanding and emotionally overwhelming. Many caregivers …
Better Sleep, Brighter Minds: Exploring Relaxation for Youth Ages 11-13
JOIN the study!The purpose of this study is to try out a new way of teaching kids and parents ways to relax and sleep skills to see if it helps youth with sleep and well-being.The study tasks can be completed entirely online (NO in-person visits required).Who can take part?Youth (ages …
Stories That Heal: Support For Moms Facing Tough Times
Many individuals who experience extremely stressful or traumatic events may feel irritable or on edge, have unpleasant memories of the event that they try to avoid, and feel more distant from others. Narrative Exposure Therapy (NET) is a treatment that can help, particularly pregnant and postpartum women who have gone …
Mmmm! I'm All IN for Kidney Health! Join Our Chronic Kidney Disease and Diet Study Contact List
What you eat matters when you have chronic kidney disease (CKD)—and researchers want to learn what works best.The IU School of Medicine is studying how diet affects kidney health and invites people with CKD to join a nutrition research contact list. By signing up, you’ll be notified about studies that …
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Browse by Featured categories
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Help Shape the Future of Health
with the Indiana Biobank
By donating a small blood sample, you can help researchers discover better treatments and improve health across Indiana.
Who Can Join?
All IU Health Patients of Any Age
What Is Involved?
It's easy-we collect a blood sample during your regular doctor visit.
Why does it Matter?
By taking part, you're helping improve care for you, your loved ones, and people across Indiana.
Recently added/updated trials
A 52-Week, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Group Sequential Study to Evaluate the Efficacy and Safety of Rilzabrutinib in Patients Aged 10 to 65 Years With Sickle-Cell Disease (Libra)
S
Seethal Jacob, MD
This is a multicenter, randomized, double-blind, placebo-controlled, parallel-group, group-sequential study (Part A), followed by an open-label LTE period (Part B) to investigate the efficacy, and safety of rilzabrutinib in participants with sickle-cell disease (SCD).THIS STUDY IS ENROLLING BY INVITATION ONLY
Vape Study: Help us Understand Nicotine Dependence with Brain Stimulation
J
Joshua Brown
Do you use nicotine-based vapes? Our study is testing the effects of brain stimulation on nicotine use and craving. Temporal interference (TI) delivers very mild electrical currents to the scalp that reach deeper brain regions linked to addiction, without surgery. You may qualify to be in this study if you:Are between the ages of 21 and 50Have at least a 6th grade education and are English-speakingVape at least 15 mg of nicotine per day (~1-2 cigarettes/day)Are not currently in treatment for nicotine use
Soccer Players, Keep Your Head in the Game—Join Our Brain Impact Recovery Study
K
Kei Kawata
We are conducting a study to see if fish oil, which contains omega-3 fatty acids like DHA and EPA, can protect soccer players' brains from repetitive head impacts. Our main goal is to determine if these omega-3s can have possible protective effects from repeated repetitive head impacts, which could lead to better brain health strategies for athletes.Current and former soccer players (with 5+ years of heading experience) who are 18 to 30 years old are invited to participate.
Caring for Caregivers: Join our study!
N
Navin Kaushal
Caring for Someone Else? Caring for Others Starts With Caring for Yourself. Caring for someone with Alzheimer’s disease or related dementia is important work—but it can also be stressful and exhausting. Many caregivers, put their own health last. As a caregiver, you deserve care, too. Our study is about supporting caregivers by helping them build a simple, at-home exercise routine right from home to improve their health and well-being.Exercise can help reduce stress, improve mood, and increase energy. This study offers free exercise equipment and virtual support to help caregivers get started and stay active.
Effect of CYP2B6 genotype and efavirenz on the disposition and pharmacodynamic of methadone and tizanidine in healthy volunteers
Z
Zeruesenay Desta
What is this study about?The purpose of this study is to see how efavirenz, a widely used medication to treat HIV infection, interacts with methadone (a medication used to treat addiction problems and pain) and tizanidine (a medication used to relax muscle) when taken at the same time. The information learned in this study will help to inform doctors as to how to appropriately adjust doses of efavirenz, methadone and tizanidine to improve health outcomes and long-term treatment success for HIV patients. Who can participate?Healthy adults who are able to refrain from taking certain medications during the study period.
Nicotinic Acid for the treatment of Alzheimer's Disease Protocol Type: Interventional
J
Jared Brosch, MD
The primary objective of this study is to collect data on the penetration of commercially available, FDA approved, extended-release niacin into the spinal fluid. One dose of 500 mg nicotinic acid will be used (in addition to placebo) to build a dose response curve for this compound in human cerebrospinal fluid. This objective will demonstrate target engagement of HCAR2 in the CNS after oral treatment with niacin. The primary endpoints are to show increased nicotinic acid levels in blood and CSF.THIS STUDY IS ENROLLING - Methods of recruitment include personal contact, database searches, (Registry IRB# 1010002668), review of medical records, identifying potential subjects who meet study criteria. Recruitment will primarily happen in Adult Neurology Clinic through Dr. Brosch’s clinical patients.
Dermatology Clinical Research Recruitment Database
E
Elizabeth Bryant, MD
The purpose of this study is to establish a recruitment database of individuals who have contacted the research staff in the department of dermatology expressing interest in participating in clinical research and requesting to be contacted if eligible to participate.
