The purpose of this study is to determine whether the quantity of peripheral blood stem cells can be made greater in the laboratory. Healthy male and female volunteer donors between the ages of 18-40 years will be used as a source of normal peripheral blood hematopoietic stem cells (HSC). Health will be assessed by history and physical. Volunteer donors between the ages of 18-40 years with X-linked chronic granulomatous disease will also be used as a source of peripheral blood HSC. X-CGD donors are likely to be male because of the sex-linked inheritance of this disease.THIS STUDY IS ENROLLING BY INVITATION ONLY - Patients with CGD are typically identified in childhood, and Pediatric Hematology/Oncology physicians tend to continue to follow these patients into adulthood due to this being a relatively rare condition that internal medicine providers do not commonly see. We limited the study to patients over 18 yo so they can provide their own consent. All subjects would be seen and collected under the Pediatric Hematology/Oncology group’s care. Family members or more typically laboratory staff are identified for the normal volunteer donors, also all adults.

The purpose of this clinical study is to obtain post-market safety and efficacy data when the V.A.C.® Peel and Place dressing is used in conjunction with 3M™ V.A.C.® Therapy.THIS STUDY IS ENROLLING BY INVITATION ONLY