Health Research
and Clinical Studies

All IN for Health provides a list of hundreds of active health studies happening right here in Indiana. These health studies are conducted by faculty at Indiana University, Purdue University, and the University of Notre Dame.

All IN for Health provides a list of hundreds of active health studies happening right here in Indiana. These health studies are conducted by faculty at Indiana University, Purdue University, and the University of Notre Dame.

Browse by Featured categories

Aging
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Covid-19 & Infectious Disease
Diabetes, Heart and Blood Vessels
Digestive System (GI), Bowel & Liver
Health Mental, Behavioral Health & Developmental Conditions
Healthy Volunteer
Cancer
Diet, Nutrition, Exercise, & Sleep

Browse by Featured categories

Aging
Children, Families & Pregnancy
Dental
Online
Alcohol, Tobacco, or Other Substance Use
Alzheimer’s Disease & Dementia
Asthma,Lungs & Allergies
Bones, Muscles and Joints
Brain, Spine & Nervous System
Covid-19 & Infectious Disease
Diabetes, Heart and Blood Vessels
Digestive System (GI), Bowel & Liver
Health Mental, Behavioral Health & Developmental Conditions
Healthy Volunteer
Cancer
Diet, Nutrition, Exercise, & Sleep

Browse by Featured categories

Aging
Alcohol, Tobacco and Substance Use
Brain, Spine and Nerves
Cancer
Diabetes
Diet, Exercise and Nutrition
Healthy Volunteers
Mental and Behavioral Health
Alzheimer’s Disease and Dementia
Autoimmune Disease
Bladder and Kidneys
Bones, Muscles and Joints
Community and Environmental Health
Dental
Eye Conditions
Genetic and Rare Conditions
GI, Liver and Pancreas
Hearing, Speech and Language
Heart Health
Infectious Disease
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Maternal, Infant and Child Health
Online Studies
Public Health Studies
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Sleep
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Thyroid, Hormones and Metabolism

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Browse studies by

Recently added/updated trials

Parkinson’s Foundation PD GENEration Genetic Registry

S
S. Elizabeth Zauber
18 years - 100 years
All genders
Who is EligibleAges 18+Diagnosis of Parkinson’s diseaseWillingness to undergo genetic testingWhat is InvolvedIn person at IUH Neuroscience Center or kit can be mailed to participant’s homeGenetic testing occurs via buccal swab or blood draw in clinic or at home, participants receive genetic counseling 
 Delivering Food Resources & Kitchen Skills (FoRKS) to Adults with Food Insecurity and Hypertension: An RCT

Delivering Food Resources & Kitchen Skills (FoRKS) to Adults with Food Insecurity and Hypertension: An RCT

D
Daniel Clark
35 years - 75 years
All genders
FoRKS is a voluntary research study designed by researchers at the IU School of Medicine in partnership with Eskenazi Health. The purpose of FoRKS is to study the effect increased food resources and kitchen skills have on health and nutrition for adults with high blood pressure in the Eskenazi Health system.  
 Children Ages 9-14 and Their Parents/Guardians Needed for Study on Middle School Transition

Children Ages 9-14 and Their Parents/Guardians Needed for Study on Middle School Transition

N
Natasha Chaku, PhD
9 years - 14 years
Accepts healthy volunteer
All genders
Is your child about to make the transition from elementary school to middle school?  Join the BURST study! What is the BURST study?The Behavior, Understanding, and Relationships During School Transition (BURST) Study aims to understand the complex relationships between puberty, cognition, social relationships, and health that occur during the transition from elementary school to middle school. We are particularly interested in how youth’s bodies and minds are changing and growing (e.g., their pubertal development, their cognitive development), their social relationships (e.g., with their parents, teachers, and friends), and their health behaviors (e.g., when they sleep, their mental health).  Who can take part?Children (ages of 9 – 14) who are about to make the transition into middle school from elementary school. 
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Online study

The natural history of C. trachomatis urethral infections in men who have sex with women

S
Stephen Jordan
18 years - 100 years
Accepts healthy volunteer
Male
What is the purpose of this study?Chlamydia is the most common bacterial sexually transmitted infection (STI) in the United States and is caused by the bacteria Chlamydia trachomatis, or “CT” for short. CT infects both men and women. The purpose of this study is to understand what causes some men to resist CT infection, spontaneously clear CT, and some to resist antibiotic cure so we can design a vaccine and lower CT rates in both men and women. We will compare samples that we collect from men who are being treated for Chlamydia to healthy samples to further study sexually-transmitted co-infections and the immune system.Who can take part?We are currently looking for healthy adult males (ages 18 and older) to participate.
 The Indiana Myeloma Registry

The Indiana Myeloma Registry

R
Rafat Abonour, MD
18 years - 100 years
All genders
Observational
WHAT IS CANCER?WHAT IS MULTIPLE MYELOMA?WHAT IS THE STUDY ABOUT?What is cancer?Each cell in your body holds a copy of your DNA. This DNA tells your cells how to do their jobs, like when to copy themselves and when to delete. Your cells copy and delete all the time. This is normal and healthy.Sometimes during the copying process, a mutation (like a typo) happens in the DNA that your body can't correct. Your cells may begin losing their ability to do their normal jobs, copying too often, and taking up too much space. This is cancer.Multiple Myeloma is cancer of the plasma cellsPlasma cells are a type of white blood cell that help fight infections by making antibodies. They are created in the bone marrow.As the mutated plasma cells grow out of control, they take over the bone marrow, leaving less space for red blood cells. This leads to a condition called anemia, which is when the blood doesn't have enough red blood cells. Red blood cells carry oxygen through the body. Without enough red blood cells, the body can't get enough oxygen.The mutated plasma cells also may take over the bone,causing pain and bone fractures. As the bone breaks down, calcium leaks into the blood. High calcium in the blood is called hypercalcemia.Mutated plasma cells make an abnormal antibody called M-protein (monoclonal protein), which can cause blockages in the kidneys. This can lead to kidney dysfunction and failure.Multiple Myeloma happens over time, usually several years. At the early stages, it is called MGUS.As more and more plasma cells get mutations, it develops into a stage called Smoldering Myeloma.Active Multiple Myeloma is diagnosed when one or more of the main symptoms (called CRAB symptoms) start to develop. These symptoms are hypercalcemia, renal (kidney) dysfunction, anemia, and bone disease.There's still a lot we don't know about Multiple Myeloma. That's why research is so important.The Indiana Myeloma Registry is a study to better understand:Who is most likely to get Multiple Myeloma?What treatments work for which people?What causes Multiple Myeloma?We hope to improve treatment and, one day, find a cure.If you have Multiple Myeloma, MGUS, Smoldering Myeloma, or other plasma cell disorder, please consider joining the study.Study PartsSALIVA SAMPLEHEALTH HISTORY QUESTION­NAIREQUALITY OF LIFE QUESTION­NAIREAPPROVAL TO LINK TO YOUR MEDICAL RECORDWe'll mail you a kit!One time: online or by phoneEvery 3-12 months: online or by phoneSo we can follow how your treatments go without you doing extra work!Study EligibilityYou are eligible if these things are true about you:You are a male or female patient age 18 or older at the time of informed consentYou have been diagnosed with or are suspected to have one of the following:Monoclonal Gammopathy of Undetermined Significance (MGUS)Smoldering Multiple MyelomaMultiple MyelomaBony or Soft Tissue PlasmacytomaPrimary AmyloidosisPlasma Cell LeukemiaOther Plasma Cell Dyscrasias (including but not limited to light chain deposition disease, monoclonal gammopathy of renal significance, POEMS syndrome)you have questions about the study, email myeloma@iu.edu or call 317.278.0808.Click here to sign up

Outcomes of Stent Placement in Adults with Idiopathic Intracranial Hypertension Patients and Venous Sinus Stenosis

B
Bradley N. Bohnstedt, MD
18 years - 100 years
All genders
Observational
What is the purpose of this study?Venous sinus stenosis has been identified as a potential etiology in Adults with Idiopathic Intracranial Hypertension (IIH). IIH can lead to significant disability including loss of vision, disabling headaches, and neurocognitive impairment. This study will analyze outcome data of stenting in adult patients with IIH and venous sinus stenosis.  THIS STUDY IS ENROLLING BY INVITATION ONLY - Participants will be evaluated in clinic or in the emergency department. Determination of intervention will be made by primary surgeon in accordance to standard of care. Patients will be asked to participate in the study if they meet our inclusion criteria.

A multicenter, single-arm, pivotal study to evaluate the safety and efficacy of the CGuard Prime carotid stent system (80cm) used in conjunction with the FDA-cleared ENROUTE Transcarotid Neuroprotection System (NPS) in patients undergoing carotid artery stenting via the Transcarotid Artery Revascularization (TCAR) approach.

R
Raghu Motaganahalli, MD
18 years - 79 years
All genders
Interventional
What is the purpose of this study?The objective of this study is to evaluate acute device and technical success of the CGuard Prime™ Carotid Stent System (80cm) when used in conjunction with the Enroute NPS during Transcarotid Artery Revascularization procedures in the treatment of carotid artery stenosis in spatients at high risk for adverse events from carotid endarterectomy.THIS STUDY IS ENROLLING BY INVITATION ONLY