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Found 594 results for IU Health Enterprise System
A listing of IU Health Enterprise System medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Randomized prospective study comparing intrathecal morphine vs intravenous methadone for postoperative analgesia following retroperitoneal lymph node dissection (RPLND)
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Gulraj Singh Chawla
At Indiana University Adult Academic Health Center (AAHC), both intrathecal morphine and intravenous methadone are the standard of care for pain management in patients undergoing retroperitoneal lymph node dissections for primary testicular cancer, and both have had great success. In this study, we propose to compare their analgesic effectiveness at …
Azithromycin Treatment for Respiratory Syncytial Virus-induced Respiratory Failure in Children
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Michael Hobson, MD
What is the purpose of this study?The overarching hypothesis of the ARRC trial is that administration of Azithromycin (AZM) during acute, Respiratory Syncytial Virus (RSV)-induced respiratory failure will be beneficial, mediated through the matrix metalloproteinase (MMP)-9 pathway. THIS STUDY IS ENROLLING BY INVITATION ONLY
A Global Multi-Center Prospective Observational Cohort to Support Drug Development in Adult Patients with Primary Sclerosing Cholangitis
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Craig Lammert, MD
What is the purpose of this study?To develop an appropriate real-world data comparator cohort to support the design, execution, and serve as an external control for interventional clinical trials in PSC. This is a Global, multi-center longitudinal observational cohort study. Collection of prospective clinical data to include liver-related clinical outcomes …
Pediatric Behavioral Health Integrated Care: Indiana Statewide Strategic Plan to Address the Growing Mental Health Crisis
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Matthew Aalsma
What is the purpose of this study?The purpose of this study is to learn more about the impact of a substance use disorder (SUD) Integrated Behavioral Health Program (IBH) on primary care providers (PCPs) willingness to engage in and views/attitudes around adolescent SUD treatment as well as IBH team dynamics. THIS …
Role of neutrophil-specific NOX2 in alcohol-induced liver injury
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Suthat Liangpunsakul, MD
What is the purpose of this study?NADPH oxidase 2 (NOX2) is the isoform of NOX found in phagocytes including neutrophils, NOX2 activation generates reactive oxygen species (ROS) with antimicrobial activities. Patients with advanced alcoholic cirrhosis or alcoholic hepatitis are more susceptible to infections due to deficient ROS production by neutrophils. …
Parent Social Buffering and Dyadic Music Intervention to Decrease Distress in Infants and Young Children during Hematopoietic Stem Cell Transplant and their Parents
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Sheri Robb
The goal of the proposed study is to adapt an existing music-based intervention (Active Music Engagement; AME) using the ORBIT model, for infants and young children (3 years of age and under) undergoing stem cell transplant and their parents. Previous studies suggest that AME produces positive psychosocial outcomes for children …
A post-market, prospective, multi-center, single-arm study evaluating the safety and efficacy of the 3M V.A.C. Peel and Place Dressing used in conjunction with 3M V.A.C.® Therapy
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Greg Westin
The purpose of this clinical study is to obtain post-market safety and efficacy data when the V.A.C.® Peel and Place dressing is used in conjunction with 3M™ V.A.C.® Therapy.THIS STUDY IS ENROLLING BY INVITATION ONLY
ARTEMIS - Effects of Ziltivekimab Versus Placebo on Cardiovascular Outcomes in Patients With Acute Myocardial Infarction
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Rolf Kreutz, MD
What is the purpose of this study?The research study is being done to see if ziltivekimab can be used to treat people who were admitted to hospital because of a heart attack. Ziltivekimab might reduce development of heart disease, thereby preventing new heart attacks or strokes.THIS STUDY IS ENROLLING BY …
Characterization of the neural correlates of anesthetic-induced intraoperative dream states using stereoelectroencephalography.
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David Purger
What is the purpose of this study?Dreams experienced during emergence from anesthesia have been associated with improvement in trauma-related psychiatric disorders. This study aims to characterize the brain network activity patterns associated with anesthetic-induced intraoperative dreams to gain insight into the underlying mechanisms of the phenomenon and its potential therapeutic …
Effects of Thrice Weekly versus Home Peritoneal Dialysis on Cardiovascular Functional Capacity (ELDEN-PD) Study
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John Christenson, MD
What is the purpose of this study?The purpose of this study is to gather information on cardiovascular changes in conventional hemodialysis, and peritoneal dialysis patients. Research indicates that cardiovascular disease remains the leading cause of death among patients with chronic kidney disease (CKD) and those on dialysis.THIS STUDY IS ENROLLING …
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