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Found 594 results for IU Health Enterprise System

A listing of IU Health Enterprise System medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Dominantly Inherited Alzheimer Network (DIAN)

M
Martin Farlow, MD
18 years - 100 years
Accepts healthy volunteer
All genders
Dominantly inherited Alzheimer's disease (AD) represents less than 1% of all cases of AD and is an important model for study because the responsible mutations have known biochemical consequences that are believed to underlie the pathological basis of the disorder. The overall purpose of this research is to understand the …

In Vitro Expansion and Gene Transfer Using Peripheral Blood Stem Cells

S
Scott Goebel, MD
Accepts healthy volunteer
All genders
The purpose of this study is to determine whether the quantity of peripheral blood stem cells can be made greater in the laboratory. Healthy male and female volunteer donors between the ages of 18-40 years will be used as a source of normal peripheral blood hematopoietic stem cells (HSC). Health …

Collection of Specimens and Clinical Data to Create a Biorepository for the Genitourinary Oncology Program

N
Nabil Adra, MD
18 years - 100 years
All genders
The purpose of this study is to collect a variety of blood and cancer tissue specimens from patients with advanced kidney, bladder or prostate cancer.

Reducing Risk of Dementia through Deprescribing: Cognitive Outcomes After AntiCholinergic Reduction (R2D2: COACH)

M
Malaz Boustani, MD
All genders
A cluster-randomized controlled trial (RCT) called "Reducing Risk of Dementia through Deprescribing" (R2D2) to evaluate the impact of a deprescribing intervention on important cognitive and safety outcomes.  This study will evaluate the effects of the use of a program to reduce prescribing of a group of commonly prescribed medications called …

MRI Placental Changes in Prenatally Diagnosed Intrauterine Growth Restriction

B
Brandon Brown, MD
18 years - 100 years
Female
Observational
The purpose of this study is to better understand intrauterine growth restriction (IUGR), which is a common diagnosis during pregnancy.

Utilizing Palliative Leaders In Facilities to Transform care for Alzheimer's Disease (UPLIFT-AD)

K
Kathleen Unroe, MD
18 years - 100 years
All genders
The purpose of this study is to evaluate a comprehensive model for integrating both primary and specialty Palliative Care into nursing facilities.

Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT

K
Karl Shively
L
Luke A. Lopas, MD
18 years - 64 years
All genders
Phase 3
Interventional
The proposed study is a multi-center, prospective randomized controlled trial comparingurrent standard of care treatment to the SEXTANT treatment protocol in patients with Typeures of the tibia and IIIB fractures of the ankle and hindfoot.

Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)

M
Mitesh Shah, MD
All genders
Observational
What is the purpose of this study?The objectives of this registry study are to evaluate real-world clinical outcomes andd outcomes that measure the effectiveness and safety of STaRT.THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not actively “recruited,” but are screened by their …

Analysis of urine sediment characteristics in nephritis using high resolution microscopy

A
Andrew Schwaderer, MD
7 years - 17 years
All genders
Observational
What is the purpose of this study?The purpose of this study is to develop a test for kidney disease that does not require a kidney biopsy or blood draw.  We will look at urine samples under a microscope and see if we find patterns in the kind of cells and …

Distal Radius Interventions for Fracture Treatment (DRIFT)

E
Erika Daley
4 years - 10 years
All genders
Interventional
This protocol describes a multicenter, prospective randomized superiority trial comparingunctional outcomes between children treated with sedated reduction versus no formalduction.
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