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Found 610 IU Health Enterprise System trials

A listing of IU Health Enterprise System medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Y
Yohan Jang
60 years - 100 years
All genders
Interventional
This study investigates the effectiveness of early surgical treatment compared to non-surgical care with early rehabilitation for pelvis fractures. A pelvis fracture is a break in one or more of the bones of the pelvis. The study focuses on patients aged 60 years or older with a specific type of …
C
Clinton Bahler, MD
18 years - 100 years
Male
This study investigates the use of a special scan called PSMA PET to guide surgery for prostate cancer. The purpose is to find out if the PSMA PET scan can better detect cancer near the edge of the prostate and help doctors plan the surgery. Prostate cancer is a disease …
E
Erica Eugster, MD
M
Manahil Mustafa
3 years - 18 years
Female
Observational
What is the purpose of this study?Extracellular vesicles (EVs) are double-membrane particles that transport proteins, microRNAs (miRNAs), and lipids, playing a crucial role in cell-to-cell communication and reflecting the cellular environment. Recent research has highlighted their potential as biomarkers and therapeutic agents in various adult conditions, yet their role in …
J
Jonathan L. Berkowitz, MD, PhD
18 years or above
All genders
Interventional
This randomized research trial studies how well serum tumor marker directed disease monitoring works in monitoring patients with hormone receptor positive Her2 negative breast cancer that has spread to other places in the body. Using markers to prompt when scans should be ordered may be as good as the usual …
S
Samer Gawrieh, MD
18 years - 100 years
All genders
Interventional
This study investigates the effects of an investigational medication on people with Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) who also have Human Immunodeficiency Virus (HIV). MASLD is a condition where fat builds up in the liver, and this study aims to see if the investigational medication can reduce this fat. …
R
Rina Yadav
18 years or above
Female
Phase 2
This study investigates the effects of an investigational medication on premenopausal women with a specific type of breast cancer called estrogen receptor-positive, HER2-negative breast cancer. The purpose of the study is to understand how the investigational medication affects tumor cell growth compared to other treatments. The study is divided into …
S
Sikandar Khan, MD
50 years - 100 years
All genders
Interventional
This study investigates the use of virtual reality (VR) brain games for people who have survived delirium after being in the intensive care unit (ICU) due to acute respiratory failure. Delirium is a condition where a person becomes very confused and disoriented. It often happens to older adults in the …
J
Jodi Skiles
20 years or below
All genders
This study investigates the use of Hematopoietic Stem Cell Transplantation (HSCT) in children with non-cancerous diseases. The purpose is to use a preparatory regimen that suppresses the immune system without destroying bone marrow to allow donor cells to engraft. The study aims to understand the main side effects of this …
J
Jodi Skiles
100 years or below
All genders
This study investigates the safety of using investigational cord blood units (CBUs) for hematopoietic stem cell transplants in both children and adults. Hematopoietic stem cells are important for creating new blood cells. The study will carefully look at any problems that happen during or after the infusion of these CBUs.Participants …
L
Larry Markham
100 years or below
All genders
This study investigates the genetic causes of thoracic aortic aneurysm (TAA) and other aortic diseases. The purpose is to find new genes that may cause these conditions and understand how genetics can affect the severity of aortic and valve diseases.Participants will provide blood and urine samples. If blood samples cannot …
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