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Found 650 IU Health Enterprise System trials
A listing of IU Health Enterprise System medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Investigating Sinonasal Therapy De-escalation in Cystic Fibrosis Patients on Investigational Therapy
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Elisa Illing
This study investigates the effects of reducing sinonasal therapies in patients with cystic fibrosis who are on cystic fibrosis transmembrane regulator (CFTR) modulator therapy. Cystic fibrosis is a genetic disorder that affects the lungs and other organs, characterized by thick, sticky mucus that can clog airways and lead to respiratory …
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Greg Durm, MD
This study investigates the safety and effects of an investigational antibody-drug conjugate in patients with advanced or metastatic solid tumors. The purpose is to understand how the investigational medication works in the body and its impact on tumors. Advanced or metastatic solid tumors are cancers that have spread beyond their …
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Domenick Zero, DDS, MS
What is the purpose of this study?The purpose of this study is to demonstrate the comparability of ianalumab exposure following the sub-cutaneous (s.c.) administration of one injection of 300 mg/2 mL auto-injector (AI) versus two injections of 150 mg/1 mL pre-filled syringe (PFS), and to evaluate the safety and tolerability …
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Christina M. Scifres, MD
What is the purpose of this study?The sponsor of this research study, KOKO Medical Inc, is evaluating a medical device to control and treat abnormal postpartum uterine bleeding or hemorrhage (excessive bleeding). The device is called the KOKO device and its use in this study is experimental. The purpose of …
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Nabil Adra, MD
This study investigates the treatment of PSMA-positive metastatic castration-resistant prostate cancer (mCRPC) using an investigational medication called AAA817. The purpose of this study is to compare the effects of AAA817 with the standard of care treatment in adults who have already been treated with certain cancer therapies but have not …
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Sharon E. Robertson
This study investigates the effects of an investigational medication on eye health in patients with recurrent or metastatic cervical cancer. Cervical cancer occurs when cells in the cervix grow uncontrollably. This study focuses on understanding any side effects related to the eyes that may arise from the treatment. A side …
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Brian Weiss
This study investigates the safety and effects of an investigational medication when combined with radiation therapy in children with high grade glioma. High grade glioma is a type of cancer that occurs in the brain. The investigational medication works by blocking signals that make cancer cells grow, which may help …
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Amanda J. Saraf, DO
This study investigates the addition of investigational medication and investigational immunotherapy to the usual chemotherapy for infants with newly diagnosed acute lymphoblastic leukemia (ALL). ALL is a type of cancer where the bone marrow makes too many immature lymphocytes (a type of white blood cell). In this study, the researchers …
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Sharon Moe, MD
This study investigates how well an investigational medication works when combined with another medicine in people with chronic kidney disease (CKD) and high blood pressure (hypertension). CKD is a condition where the kidneys are damaged and can't filter blood as well as they should. Hypertension is when the blood pressure …
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Seethal Jacob, MD
This study investigates the effects and safety of an investigational medication in people with sickle-cell disease (SCD). SCD is a condition where red blood cells become hard and sticky, which can cause pain and other health problems. The study is designed to see how well the medication works and how …
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