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Found 610 IU Health Enterprise System trials
A listing of IU Health Enterprise System medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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Sandeep Batra, MD
This study investigates treatment options for juvenile myelomonocytic leukemia (JMML), a rare type of blood cancer that affects young children. JMML is a condition where the bone marrow makes too many white blood cells, which can lead to various health problems. The purpose of this study is to test the …
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Charles Powell, MD
This study investigates the collection of signals from the sacral nerve when it is stimulated. The sacral nerve is a part of the nervous system that can affect bladder and bowel function. The study uses special systems to collect signals from this nerve to better understand how the nerve works …
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Lisa Landrum, MD, PhD, MS
This study investigates the effectiveness of using a combination of investigational medications, nivolumab and ipilimumab, compared to nivolumab alone in treating patients with recurrent endometrial cancer. Endometrial cancer is a type of cancer that begins in the lining of the uterus. This study focuses on a specific type of endometrial …
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Sharon E. Robertson
This study investigates the safety of using chemoradiation instead of surgery for early stage vulvar cancer. Vulvar cancer is a type of cancer that affects the external female genitalia. In some cases, cancer spreads to nearby lymph nodes. This study looks at patients with a macrometastasis, which means the cancer …
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Monika Fischer, MD
What is the purpose of this study?The main aim of this study is to learn whether vedolizumab and upadacitinib given together (also called dual targeted therapy or DTT) reduces bowel inflammation and ulcers in the bowel compared to vedolizumab only (also called monotherapy) in adults with moderately or severely active …
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Anna Elizabeth Thomas
This study investigates the safety and effects of an investigational medication for treating infections caused by gram-negative bacteria in newborns and infants. Gram-negative bacteria are a type of bacteria that can cause various infections and are known for their resistance to antibiotics. The investigational medication is a combination of two …
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Rick Nelson, MD
What is the purpose of this study?This study aims to evaluate the safety and efficacy of cochlear implantation for adults with bilateral sensorineural hearing loss who currently do not meet the FDA-approved indications for cochlear implantation. Following cochlear implantation, participants will complete speech perception assessments and questionnaires over the course …
Investigating Sinonasal Therapy De-escalation in Cystic Fibrosis Patients on Investigational Therapy
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Elisa Illing
This study investigates the effects of reducing sinonasal therapies in patients with cystic fibrosis who are on cystic fibrosis transmembrane regulator (CFTR) modulator therapy. Cystic fibrosis is a genetic disorder that affects the lungs and other organs, characterized by thick, sticky mucus that can clog airways and lead to respiratory …
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Steven Rhodes
What is the purpose of this study?The trial will be an open label, single arm, phase 2 study in 20 participants. The study will assess the tolerability and efficacy of HLX-1502 in participants with NF1 16 years of age or older with progressive and/or symptomatic PN. THIS STUDY IS ENROLLING BY …
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Nicolas Barros, MD
This study investigates the effects and safety of an investigational medication for treating candidemia and invasive candidiasis, which are serious fungal infections caused by Candida species. Candidemia is a bloodstream infection, while invasive candidiasis occurs when the infection spreads beyond the bloodstream to other parts of the body.Participants will receive …
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