Found 607 IU Health Enterprise System trials
A listing of IU Health Enterprise System medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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Kathy Miller, MD
This study investigates the effects of an investigational medication alone compared to the same medication combined with tocilizumab in patients with advanced breast cancer. Advanced breast cancer includes conditions such as metastatic triple negative or ER-low breast cancer. This study involves Black and non-Black patients and aims to understand how …
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Tarah Ballinger, MD
This study investigates how genetic ancestry affects the completion of treatment in patients diagnosed with breast cancer. Breast cancer is a disease where cells in the breast grow out of control. This study involves newly diagnosed women with stages I-III breast cancer who self-report as Black or White.Participants will provide …
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Nawal Kassem
This study investigates how to increase genetic testing in Black families with hereditary cancer syndromes. Hereditary cancer syndromes are conditions where gene changes increase the risk of cancer in families. The study focuses on Black patients who have been advised to undergo genetic testing. It aims to see if using …
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Namita Agrawal
This study investigates the feasibility of adding pre-rehabilitation pelvic health physical therapy to the standard radiation treatment plan for women with certain types of cancer. These include cervical, vaginal, vulvar, uterine, or anal cancer. Participants will receive education on using a vaginal dilator during their treatment. The study will also …
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Michael W. Sim, MD
This study investigates a new approach for treating HPV-positive oropharyngeal squamous cell carcinoma (OPSCC). The purpose of this study is to see if reducing the intensity of treatment, based on levels of ctHPVDNA (pieces of cancer DNA in blood samples), can be as effective as the standard treatment. OPSCC is …
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Samantha Armstrong
What is the purpose of this study?This phase II trial compares the effect of immunotherapy (pembrolizumab) plus chemotherapy (doxorubicin) to chemotherapy (doxorubicin) alone in treating patients with undifferentiated pleomorphic sarcoma (UPS) or a related poorly differentiated sarcoma that has spread from where it first started to other places in the …
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Anita Turk, MD
The purpose of this study is to investigate how a combination of treatments, including an investigational medication, carboplatin, paclitaxel, and radiation, works for people with early-stage anal cancer. Anal cancer is a disease where cancer cells form in the tissues of the anus. This study will look at how well …
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Thankam Thyvalikakath
This study is looking at finding biomarkers in blood and saliva samples that will help detect the symptoms of Sjrogrens disease earlier than current diagnosis time. Sjögren's disease is an autoimmune disease that affects the mucous membranes and moisture-secreting glands of your eyes and mouth, resulting in decreased tears and …
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Greg Durm, MD
This study investigates the safety and effects of an investigational antibody-drug conjugate in patients with advanced or metastatic solid tumors. The purpose is to understand how the investigational medication works in the body and its impact on tumors. Advanced or metastatic solid tumors are cancers that have spread beyond their …
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Nabil Adra, MD
This study investigates the treatment of PSMA-positive metastatic castration-resistant prostate cancer (mCRPC) using an investigational medication called AAA817. The purpose of this study is to compare the effects of AAA817 with the standard of care treatment in adults who have already been treated with certain cancer therapies but have not …
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