Found 594 results for IU Health Enterprise System
A listing of IU Health Enterprise System medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Randomized Phase Iii Study of Mosunetuzumab Vs. Rituximab for Low Tumor Burden Follicular Lymphoma
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Khushali Jhaveri
This phase III trial compares the effectiveness of rituximab to mosunetuzumab in treating patients with follicular lymphoma with a low tumor burden. Rituximab is a monoclonal antibody. It binds to a protein called CD20, which is found on B cells (a type of white blood cell) and some types of …
A Randomized Phase Ii Study of Venetoclax and Hma-Based Therapies for the Treatment of Older and Unfit Adults with Newly Diagnosed Flt3-Mutated Acute Myeloid Leukemia (Aml): A Myelomatch Treatment Trial
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Rita Assi
This phase II MyeloMATCH treatment trial compares the usual treatment of azacitidine and venetoclax to the combination treatment of azacitidine, venetoclax and gilteritinib in treating older and unfit patients with acute myeloid leukemia and FLT3 mutations. Azacitidine is a drug that is absorbed into DNA and leads to the activation …
A Randomized, Open-Label Study Evaluating The Efficacy And Safety Of Cemacabtagene Ansegedleucel In Participants With Minimal Residual Disease After Response To First Line Therapy For Large B-Cell Lymphoma (Alpha3)
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Varun Mittal
This is a randomized, open-label study in adult patients who have completed standard first line therapy for large B-cell lymphoma (LBCL) and achieved a complete response or partial response suitable for observation, but who have minimal residual disease (MRD) as detected by the Foresight CLARITY™ Investigational Use Only (IUO) MRD …
Randomized, Open-Label Study of the Bria-Imt Regimen and Check Point Inhibitor Vs Physician S Choice in Advanced Metastatic Breast Cancer (Bria-Abc)
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Tarah Ballinger, MD
The purpose of this study is to evaluate the effect of the Bria-IMT regimen in combination with Check Point Inhibitor (CPI) on overall survival (OS) compared to treatment of physician’s choice (TPC) chemotherapy in patients with metastatic breast cancer with no approved alternative therapies available as per the Inclusion criter …
Together for Tomorrow: Explore New Treatment Options for Lung Cancer
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Vijaya L. Kakani, MD
We understand that living with non-small cell lung cancer (NSCLC), especially with the KRAS G12C mutation, can be incredibly challenging. Many people with lung cancer go through hard treatments and tough side effects. That's why we're inviting adults (ages 18 and older) who have advanced or metastatic nonsquamous NSCLC to participate …
Mmmm! I'm All IN for Kidney Health! Join Our Chronic Kidney Disease and Diet Study Contact List
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Sharon Moe, MD
What you eat matters when you have chronic kidney disease (CKD)—and researchers want to learn what works best.The IU School of Medicine is studying how diet affects kidney health and invites people with CKD to join a nutrition research contact list. By signing up, you’ll be notified about studies that …
A Phase Ii Single-Arm Pilot Study of Hydroxychloroquine for the Treatment of Aromatase Inhibitor-Associated Musculoskeletal Syndrome (Aimss)
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Tarah Ballinger, MD
The purpose of this study is to evaluate the effectiveness of hydroxychloroquine sulfate (a type of drug commonly used to treat joint pain caused by inflammation, swelling) in reducing joint pain associated with Aromatase Inhibitor Associated Musculoskeletal Syndrome (AIMSS) for patients with breast cancer.Interested in participating? For more information about …
Still Feeling Stuck? Consider a Clinical Study for Depression
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Susan Conroy, MD PhD
The purpose of this trial is to measure depressive symptoms following treatment with ALTO-207 compared with placebo in participants with TRD. This study will take place in Indianapolis, IN.
Implementing the Addressing Symptoms with Person-Centered Treatment (ADAPT) Program in Heart Failure Care
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Lyndsay DeGroot
Are you 40 years of age or older and living with heart failure? You may be able to join a study testing a new way to support people with heart failure from home.Heart failure can affect more than your heart. Living with this condition can bring challenges that are not …
Molecular Genetics Of Heterotaxy And Related Congenital Heart Defects
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Stephanie Ware, MD
Heterotaxy syndrome is a rare birth defect that involves the heart and other organs. Many cases are genetic. Fundamental lack of information about the genetic basis of heterotaxy and related congenital heart defects in the vast majority of children has hindered management and therapy. The study outlined in this protocol …
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