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Found 645 IU Health Enterprise System trials

A listing of IU Health Enterprise System medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Evaluation of the GORE® Ascending Stent Graft in the Treatment of Lesions of the Ascending Aorta

J
Joel Corvera, MD
18 years - 100 years
All genders
Interventional
What is this study about?The primary objective of ARISE II is to assess the safety and effectiveness of the GORE® Ascending Stent Graft device in the treatment of lesions involving the ascending aorta and aortic arch. THIS STUDY IS ENROLLING BY INVITATION ONLY
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AAA-SHAPE Pivotal Trial: Abdominal Aortic Aneurysm Sac Healing and Prevention of Expansion

R
Raghu Motaganahalli, MD
18 years - 100 years
All genders
Interventional
Why is this study being done?To determine the safety and effectiveness of IMPEDE-FX RapidFill to improve AAA sac behavior when used with EVAR stent graft treatment. THIS STUDY IS ENROLLING BY INVITATION ONLY
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Study on Vascular Stent for Leg Artery Blockages

G
Greg Westin
18 years - 100 years
All genders
Interventional
This study investigates the safety and effectiveness of an investigational vascular stent system for treating peripheral artery disease. Peripheral artery disease is a condition where the arteries in the legs become narrowed or blocked, which can cause pain and other symptoms. The investigational stent will be used to treat blockages …
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A Phase 3, Double-Blind, Randomized, Placebo-Controlled Study of Levosimendan in Pulmonary Hypertension Patients With Heart Failure With Preserved Left Ventricular Ejection Fraction (PH-HFpEF)

A
Ankit Desai
18 years - 85 years
All genders
Phase 3
Interventional
What is the purpose of this study?The study will evaluate the efficacy and safety of chronic oral levosimendan compared with placebo in PH-HFpEF subjects. This subject population represents a large and growing group with no established therapies to treat their PVD and RV dysfunction. Levosimendan and its prolonged active metabolite, …
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An open-label, phase II proof-of-concept study to evaluate the clinical efficacy and safety of tapinarof for adult patients with palmoplantar keratoderma

D
David Rosmarin
18 years - 75 years
All genders
Phase 2
Interventional
What is the purpose of this study?This study is being done to find out how safe and how well the drug Tapinarof (VTAMA) works for stopping or treating palmoplantar keratoderma, which is a condition characterized by thickened skin on your palms and soles. Tapinarof, used as a topical 1% cream, …
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Researching Endovascular Treatment for Intracranial Aneurysms

B
Bradley N. Bohnstedt, MD
18 years - 80 years
All genders
Interventional
This study investigates the safety and effectiveness of a special device called the Guardian Flow Diverter System for treating certain types of brain aneurysms. Brain aneurysms are bulges in blood vessels in the brain that can be dangerous if they burst. The study focuses on unruptured aneurysms that are located …
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OnX Liver Assessment Solution Clinical Study

R
Raj Vuppalanchi, MD
22 years - 80 years
All genders
Interventional
What is the purpose of this study?This protocol’s primary aim is to assess the performance of the OnX exam on patients with suspected or confirmed liver disease with the goal of comparing the OnX output stiffness estimates to FibroScan® liver stiffness measurements. Our primary objectives are to assess whether the …
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Supplementation of Skeletal Survey with Whole Body MRI for Fracture Detection in Children with Suspected Physical Abuse

C
Christopher Newman
2 years or below
All genders
Interventional
What is the purpose of this study?Children with a skeletal survey for suspected physical abuse who are already receiving MR imaging for possible neurological injuries will be imaged with additional whole body MRI. They will also receive a clinical follow up skeletal survey, which will serve as the reference standard …
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A Randomized, Double-blind, Placebo-Controlled, Multicenter, Phase 3 Study to Evaluate the Safety, Tolerability, and Efficacy of XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures

P
Phuongthao Quan
18 years - 100 years
All genders
Phase 3
Interventional
What is the purpose of this study?This is a Phase 3, multicenter, randomized, double-blind, placebo-controlled study to evaluate the clinical efficacy, safety, and tolerability of XEN1101 administered as adjunctive treatment in adult subjects diagnosed with generalized epilepsy and experiencing probable or possible PGTCS (with or without other subtypes of generalized …
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A Randomized, Double-Blind, Placebo-Controlled Phase II Study to Determine the Safety and Efficacy of Oral Ifetroban in Patients With Idiopathic Pulmonary Fibrosis (IPF)

D
Damien G. Patel, MD
40 years - 100 years
All genders
Phase 2
Interventional
What is the goal of this study?Ifetroban prevents and treats lung fibrosis due to multiple causes (bleomycin, genetic, radiation). The purpose of this study is to determine the safety and efficacy of oral ifetroban compared to placebo in subjects with IPF. THIS STUDY IS ENROLLING BY INVITATION ONLY  
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