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Found 607 iu-health-enterprise-system trials

A listing of iu-health-enterprise-system medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Immune Mechanisms of Hypertension and Cardiovascular Disease
M
Meena Madhur
18 years - 85 years
Accepts healthy volunteer
All genders
Why is this study being done?The Division of Clinical Pharmacology at Indiana University is looking for volunteers with and without high blood pressure to participate in a research study to better understand how the immune system regulates blood pressure and cardiovascular disease.  This study will look at the differences in …
J
James Tisdale
18 years - 100 years
All genders
Interventional
What is the purpose of this study?Atrial fibrillation/ atrial flutter are common irregular heart beats or arrhythmias that causes quivering of the heart and sometimes a very fast heart rate and can lead to blood clots and strokes.  Many of the current drugs on the market used to treat atrial …
T
Tarah Ballinger, MD
18 years - 100 years
Female
This study investigates the use of the NearWave optical molecular monitoring system to track the progress of breast cancer treatment. The purpose is to see if this system can predict how well patients respond to chemotherapy before surgery. Breast cancer is a disease where cells in the breast grow uncontrollably. …
M
Monika Fischer, MD
18 years - 100 years
All genders
Phase 2
Interventional
Crohn's disease (CD) develops because of a disruption of homeostasis between the gut microbiota and the host immune system resulting in excessive inflammation in the intestinal tract. Current drug therapies for CD are directed at the immune system. The emergence of fecal microbiota transplantation (FMT) for the treatment of recurrent …
C
Carmella Evans-Molina, MD
18 years - 50 years
All genders
Phase 1/2
Interventional
Researchers at City of Hope (California), University of Alabama at Birmingham, and Indiana University are studying a medication called denosumab as a potential treatment for people with type 1 diabetes. Denosumab, also known as Prolia, is a drug that has been approved by the Food and Drug Administration for bone …
Prebiotics in Women’s Health and Aging:  The Gut-Bone Connection
B
Brenda Smith
60 years - 75 years
Accepts healthy volunteer
Female
What is the purpose of this study?Dietary supplementation with dried plums has been shown to reduce bone loss in women. The purpose of this research study is to understand how dried plums are doing this by studying the immune cell, gut microbe, and bone responses.Who can take part?Women between the …
Exploring Treatment Options After Lung Cancer Surgery
V
Vijaya L. Kakani, MD
18 years - 100 years
All genders
Phase 3
Interventional
Do you have non-small cell lung cancer (NSCLC) but the cancer was not fully removed by surgery? You may qualify for a study exploring treatment options for NSCLC.This research study is testing whether adding a medication called sacituzumab tirumotecan to pembrolizumab after surgery may help prevent non-small cell lung cancer …
J
Jared Brosch, MD
60 years - 85 years
All genders
Phase 1/2
This study investigates the use of an investigational medication for treating Alzheimer's disease, a condition that affects memory and thinking. The purpose of this study is to collect data on how well the investigational medication, which is a form of vitamin B3, reaches the spinal fluid. This will help understand …
M
Misty D. Shields, MD, PhD
18 years - 100 years
All genders
Phase 1/2
This study investigates the effects of a combination of investigational medications in treating non-small cell lung cancer (NSCLC) that has transformed into small cell lung cancer (SCLC). NSCLC is a type of lung cancer that starts in the cells lining the lungs, while SCLC is a faster-growing form of lung …
E
Erick Forno
6 years - 20 years
All genders
Observational
The purpose of this research is to learn more about how the levels of different lipids affect kids with asthma and obesity. We're especially interested in how it affects kids with certain characteristics or types of asthma. In the long term, we hope this will help us understand if taking …
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