Found 594 results for iu-health-enterprise-system
A listing of iu-health-enterprise-system medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Exploring Treatment Options After Lung Cancer Surgery
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Vijaya L. Kakani, MD
Do you have non-small cell lung cancer (NSCLC) but the cancer was not fully removed by surgery? You may qualify for a study exploring treatment options for NSCLC.This research study is testing whether adding a medication called sacituzumab tirumotecan to pembrolizumab after surgery may help prevent non-small cell lung cancer …
A Phase II Study of Pembrolizumab, Carboplatin, Paclitaxel, and Radiationfor the Treatment of Early-Stage Anal Cancer
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Anita Turk, MD
Primary Objective:1. To determine the clinical complete response rate (cCR) assessed following weekly carboplatin and paclitaxel in combination with pembrolizumab and radiation for the treatment of early-stage anal cancer. Secondary Objectives:1. To assess the safety and tolerability of weekly carboplatin and paclitaxel in combination with pembrolizumab and radiation for the treatment …
Women Needed for Early Detection of Sjögren’s Disease Study
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Thankam Thyvalikakath
This study is looking at finding biomarkers in blood and saliva samples that will help detect the symptoms of Sjrogrens disease earlier than current diagnosis time. Sjögren's disease is an autoimmune disease that affects the mucous membranes and moisture-secreting glands of your eyes and mouth, resulting in decreased tears and …
Nicotinic Acid for the treatment of Alzheimer's Disease Protocol Type: Interventional
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Jared Brosch, MD
The primary objective of this study is to collect data on the penetration of commercially available, FDA approved, extended-release niacin into the spinal fluid. One dose of 500 mg nicotinic acid will be used (in addition to placebo) to build a dose response curve for this compound in human cerebrospinal …
Phase I/II Trial of Lurbinectedin with Osimertinib in Transformed Small Cell Lung Cancer
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Misty D. Shields, MD, PhD
Primary Objective:To assess the efficacy of the combination of lurbinectedin with osimertinib in patients with EGFR altered non-small cell lung cancer (NSCLC) with documented transformation to SCLC, after the use of EGFR tyrosine kinase inhibitor osimertinib.Secondary ObjectiveTo evaluate the safety of the combination of lurbinectedin with osimertinib in patients with …
Triptorelin and Protection of Ovarian Reserve in Adolescents and Young Adults with Cancer
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Tarah Ballinger, MD
This phase III trial compares the effect of giving triptorelin vs no triptorelin in preventing ovarian damage in adolescents and young adults (AYAs) with cancer receiving chemotherapy with an alkylating agents. Alkylating agents are part of standard chemotherapy, but may cause damage to the ovaries. If the ovaries are not …
PATIENTS PERSPECTIVES ON TREATMENT DECISION-MAKING AND THE ACCEPTABILITY AND USABILITY OF THE INTERACTIVE WEB-ENABLED COMMUNICATION RESOURCES OF THE CLL/SLL CARE ROAD MAP
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Larry Cripe, MD
The purpose of the study is to understand how people think about choosing between two or more treatment options and then to seek their reactions to the CLL Mind Map and Patient First Resources. Interested in participating? For more information about this research study or other cancer-related clinical trials at Indiana …
Liver Research Study for Heavy Drinkers
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Raj Vuppalanchi, MD
Do you have liver damage because of excessive alcohol use? Join our study!Researchers at the Indiana University School of Medicine are looking for adult volunteers to take part in a study looking at the link between heavy drinking and liver disease.Your participation may help researchers to gain knowledge that may …
Evaluating Financial Barriers to Breast Cancer Patients Participating in Clinical Trials
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Kathy Miller, MD
The purpose of this study is to understand the indirect costs (i.e., lost income, travel costs, parking costs, etc.) taken on by breast cancer patients who have enrolled in cancer clinical trials.Interested in participating? For more information about this research study or other cancer-related clinical trials at IU Simon Comprehensive …
Circulating Tumor Dna in High-Risk Stage I and Clinical Stage II Germ-Cell Tumors
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Nabil Adra, MD
Circulating tumor DNA (ctDNA) is a biomarker that shows how well the body responds to treatment for a disease. Blood and tissue specimens will be collected from patients to find out whether ctDNA can be detected in those specimens so that tools can be developed to predict the presence (or …
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