Found 594 results for iu-health-enterprise-system
A listing of iu-health-enterprise-system medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
A Non-randomized Open-label Multi-center Phase I/II Study of Phosphatidylinositol-3-kinase (PI3K) Inhibitor Copanlisib in Pediatric Patients With Relapsed/Refractory Solid Tumors or Lymphoma
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James Croop, MD, PhD
This study is designed to investigate whether the use of copanlisib is safe, feasible and beneficial to pediatric patients with solid solid tumors or lymphoma that are recurrent or refractory to standard therapy.
Analysis of DRC in lung disease
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Catherine Sears, MD
The DNA repair capacity (DRC) is a measure of a cell’s ability to repair DNA damage. High levels of DNA damage are observed in many lung diseases, including lung cancer and chronic obstructive lung disease (COPD, sometimes referred to as emphysema or chronic bronchitis). We believe that patients with a …
Testing the Addition of Chemotherapy Drug, Cisplatin, to Usual Radiation Therapy for Patients with Head and Neck Cancer
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Greg Durm, MD
The purpose of this study is to compare two treatment approaches that are currently used after surgery for head and neck cancer. One approach is to administer radiation therapy alone. A second approach is to administer radiation therapy along with the chemotherapy drug, cisplatin.
Indiana Biobank – Help Shape the Future of Medicine with the Indiana Biobank!
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Tatiana Foroud
The Indiana Biobank is a research study started in 2010 by Indiana University School of Medicine and IU Health. The Indiana Biobank is like a giant library—but instead of books, it holds over 60,000 blood and other samples. Each sample is connected to the person’s medical records. The person’s name and …
Alnylam ALN-APP-001: Phase I, placebo-controlled trial of ALN-APP in participants with Early-Onset Alzheimer’s disease
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Jared Brosch, MD
Who is Eligible Ages 18+ Must have had symptoms of Alzheimer’s disease prior to age 65 Diagnosis of Alzheimer’s disease Must be able to complete MRI Must be able to tolerate lumbar puncture No history of seizures, stroke or cancer in the last 5 years What is Involved In-person visits …
De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)
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Naoyuki Saito, MD
This Phase III Trial evaluates whether breast conservation surgery and endocrine therapyults in a non-inferior rate of invasive or non-invasive ipsilateral breast tumorurrence (IBTR) compared to breast conservation with breast radiation and endocrineherapy. Interested in participating? For more information about this research study or other cancer-related clinical trials at IU Simon …
Maintenance Oral Etoposide or Observation Following High-dose Chemo for GCT
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Nabil Adra, MD
This is an open label randomized phase II trial of maintenance oral etoposide vs. observationwith relapsed GCT treated with high-dose chemotherapy (HDCT) and peripheral-blood(PBSCT). Interested in participating? For more information about this research study or other cancer-related clinical trials at IU Simon Comprehensive Cancer Center, please contact:IU Clinical Trials Office Email: iutrials@iu.edu Phone: …
A PHASE III TRIAL OF THE IMPACT OF SENTINEL LYMPH NODE MAPPING ON PATIENT REPORTED LOWER EXTREMITY LIMB DYSFUNCTION IN ENDOMETRIAL CANCER
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Lisa Landrum, MD, PhD, MS
This phase III trial compares the effect of sentinel lymph node mapping to standard lymph node dissection in reducing the risk of swelling in the legs (lymphedema) in patients undergoing a hysterectomy for stage I endometrial cancer. Standard lymph node dissection removes lymph nodes around the uterus during a hysterectomy …
Multimodal Fetal and Placental Imaging and Biomarkers of Clinical Outcomes in Opioid Use Disorder
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David Haas, MD
Why is this study being done?This research study is being done to improve outcomes in mothers who have taken opioids during pregnancy and their newborn babies. We want to learn more about how the placenta functions and how the fetal brain develops when exposed to opioids. We also want to …
VOLUNTEERS NEEDED: Asthma, COPD, CF, or Healthy! Support LUNG HEALTH by being AWARE!
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Erick Forno
Are you interested in TECHNOLOGY? Join our AWARE (Acoustic Waveform Respiratory Evaluation) Research Study! Why is this study being done?Researchers at the Indiana University School of Medicine are doing a research study to understand how well smartphone technology can measure the size of your airways and if it can help diagnose …
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