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Found 607 iu-health-enterprise-system trials

A listing of iu-health-enterprise-system medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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S
Shadia Jalal, MD
18 years or above
All genders
The purpose of this study is to investigate a rapid autopsy program for patients with Small Cell Lung Cancer (SCLC) at the Indiana University Simon Comprehensive Cancer Center. Small Cell Lung Cancer is a type of lung cancer characterized by fast-growing tumors. This study will involve collecting tumor tissue from …
T
Tarah Ballinger, MD
18 years - 60 years
Female
Phase 3
This study investigates whether adding chemotherapy to ovarian function suppression and hormone therapy improves breast cancer-free survival in premenopausal women. The focus is on those with early-stage breast cancer that is estrogen receptor-positive and HER2-negative. The study will compare outcomes between those receiving chemotherapy in addition to hormone treatments and …
L
Lisa Landrum, MD, PhD, MS
18 years - 100 years
Female
Phase 2
This study investigates the effectiveness of using a combination of investigational medications, nivolumab and ipilimumab, compared to nivolumab alone in treating patients with recurrent endometrial cancer. Endometrial cancer is a type of cancer that begins in the lining of the uterus. This study focuses on a specific type of endometrial …
A
Attaya Suvannasankha, MD
18 years - 95 years
All genders
This study investigates a treatment for multiple myeloma, a type of cancer that affects plasma cells in the bone marrow. The purpose of the study is to see if the investigational treatment can improve cancer outcomes and bone health.Participants will have standard clinical assessments, such as blood draws and bone …
Study to Evaluate Weight Gain as Assessed by Change in BMI Z-score in Pediatric Subjects With Schizophrenia or Bipolar I Disorder
L
Leslie Hulvershorn, MD, MSc
10 years - 17 years
All genders
Phase 3
Interventional
To compare changes in body mass index (BMI) Z-score following treatment with OLZ/SAM vs olanzapine
B
Bharathi Muthusamy
18 years - 100 years
All genders
This study investigates the stigma experienced by patients with lung cancer and other tobacco-related cancers, such as pancreatic adenocarcinoma, renal cell carcinoma, and urothelial carcinoma. A stigma is a mark of disgrace associated with a particular condition. The purpose of this study is to understand how stigma affects patients with …
L
Leslie Hulvershorn, MD, MSc
10 years - 17 years
All genders
Phase 3
Interventional
This study investigates the safety and tolerability of an investigational medication in young people with schizophrenia or bipolar disorder.  Schizophrenia is a mental disorder that affects how a person thinks, feels, and behaves. Bipolar disorder is a condition that causes extreme mood swings, including emotional highs (mania or hypomania) and lows (depression)
S
Sharon E. Robertson
18 years - 100 years
Female
Phase 2
This study investigates the safety of using chemoradiation instead of surgery for early stage vulvar cancer. Vulvar cancer is a type of cancer that affects the external female genitalia. In some cases, cancer spreads to nearby lymph nodes. This study looks at patients with a macrometastasis, which means the cancer …
N
Nasser Hanna, MD
18 years - 100 years
All genders
Phase 2
Interventional
This study investigates the use of circulating tumor DNA (ctDNA) to personalize treatment for patients with stage III non-small cell lung cancer (NSCLC). The purpose is to use ctDNA analysis to guide therapy decisions, instead of relying solely on clinical or radiographic evidence of disease. This approach aims to tailor …
M
Monika Fischer, MD
18 years - 65 years
All genders
Phase 3
Interventional
What is the purpose of this study?The main aim of this study is to learn whether vedolizumab and upadacitinib given together (also called dual targeted therapy or DTT) reduces bowel inflammation and ulcers in the bowel compared to vedolizumab only (also called monotherapy) in adults with moderately or severely active …
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