A listing of iu-health-enterprise-system medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This study investigates cardiovascular risk in people who have recently had a heart attack, known as an acute coronary syndrome (ACS). The purpose is to understand how an investigational medication might affect heart health in individuals with a specific genetic makeup. Participants must have a certain genetic profile to take …
This study investigates the effects of using a tri-layer amnion graft or a single-layer amnion graft for patients with hard-to-heal diabetic foot ulcers (DFUs) and venous leg ulcers (VLUs). These ulcers are wounds that are difficult to heal and may require special treatments. The study compares these treatments to a …
The purpose of this study is to collect biological samples (like blood, urine, saliva, nasal swabs, and breast milk) and personal health information about your health and your pregnancy. The samples and information will be used in research studies in the future. This collection of biological samples and health information …
The purpose of this study is to identify major causes of Acute Kidney Injury (AKI) in the emergency care and hospital settings, to effectively risk-stratify patients, and, ultimately, to prevent or minimize the extent of AKI and subsequent severe health outcomes. The overarching, long-term goal of this research study is …
What is the purpose of this study?The primary goals of this study are to determine the risk factors for decline in kidney function and to define how a progressive decline in kidney function impacts neurocognitive function and behavior; the risk factors for cardiovascular disease; and growth failure and its associated …
In recent years, many complications have been attributed to breast implants including chronic fatigue and other symptoms associated with autoimmune diseases, called Breast Implant Illness (BII). Some women have even developed a rare type of T-cell non-Hodgkin’s lymphoma around their breast implants, called BIA-ALCL. Hundreds of women have been affected …
Who is Eligible Ages 18+ Must have had symptoms of Alzheimer’s disease prior to age 65 Diagnosis of Alzheimer’s disease Must be able to complete MRI Must be able to tolerate lumbar puncture No history of seizures, stroke or cancer in the last 5 years What is Involved In-person visits …
Obesity prevalence in persons with T1D has increased, which further complicates managementd risk for complications. The proposed study is relevant to public health because it helps us understand the role of the gut microbiome in disease pathophysiology in T1D youth withbesity as well as potential mechanisms to modify disease.
TReatment for ImmUne Mediated PathopHysiology (TRIUMPH) is a multi-center, three arm,domized, controlled trial of immunosuppressive therapy for children with acute liverure. The study will determine if suppressing inflammatory responses with eitherds or equine anti-thymocyte globulin therapy improves survival for children withhis rare, life-threatening condition.
Nonalcoholic fatty liver disease (NAFLD) is a spectrum of liver conditions associated withumulation that ranges from benign, non-progressive liver fat accumulation to severever injury, cirrhosis, and liver failure. NAFLD is the most common liver disease in USdults and the second leading cause for liver transplantation in the US. The natural …